diff --git a/cmake/spheral/SpheralPRT.cmake b/cmake/spheral/SpheralPRT.cmake
index e73963965..125da9df0 100644
--- a/cmake/spheral/SpheralPRT.cmake
+++ b/cmake/spheral/SpheralPRT.cmake
@@ -2,6 +2,19 @@
 #                                   Spheral_Python_Runtime_Env
 #----------------------------------------------------------------------------------------
 
+
+set(SPHERAL_PIP_CACHE_DIR ~/.cache/spheral_pip)
+if (DEFINED ENV{SYS_TYPE})
+  set(SPHERAL_PIP_CACHE_DIR ${SPHERAL_PIP_CACHE_DIR}/$ENV{SYS_TYPE})
+endif()
+set(SPHERAL_PIP_CACHE_DIR ${SPHERAL_PIP_CACHE_DIR}/${CMAKE_CXX_COMPILER_ID}-${CMAKE_CXX_COMPILER_VERSION})
+
+
+add_custom_target(clean_pip_cache
+  COMMAND rm -rf ${SPHERAL_PIP_CACHE_DIR}
+  )
+
+
 function(Spheral_Python_Env target_name)
 
   # Define our arguments
@@ -16,13 +29,55 @@ function(Spheral_Python_Env target_name)
     list(APPEND REQUIREMENTS_ARGS ${SPHERAL_ROOT_DIR}/scripts/${_req})
   endforeach()
 
-  add_custom_target(${target_name} ALL
-    COMMAND ${Python3_EXECUTABLE} -m venv --system-site-packages ${${target_name}_PREFIX}/.venv;
-    COMMAND . ${${target_name}_PREFIX}/.venv/bin/activate &&
-            python -m pip install --cache-dir ~/spheral-pip-cache --upgrade pip &&
-            python -m pip install --cache-dir ~/spheral-pip-cache ${REQUIREMENTS_ARGS}
-    DEPENDS Python3::Python
+  #TODO: Remove this once blueos3 is no longer supported.
+  set(SPHERAL_USE_SITE_PACKAGES_OPT )
+  if($ENV{SYS_TYPE} STREQUAL "blueos_3_ppc64le_ib_p9")
+    set(SPHERAL_USE_SITE_PACKAGES_OPT --system-site-packages)
+    set(PIP_INSTALL_CMD env MPICC=${MPI_C_COMPILER} MPICXX=${MPI_CXX_COMPILER} CC=${CMAKE_C_COMPILER} CXX=${CMAKE_CXX_COMPILER} 
+                        python -m pip install 
+                        --disable-pip-version-check 
+                        --no-build-isolation 
+                        -f ${SPHERAL_PIP_CACHE_DIR})
+
+    add_custom_target(${target_name} ALL
+      COMMAND ${Python3_EXECUTABLE} -m venv --system-site-packages ${${target_name}_PREFIX}/.venv;
+      COMMAND . ${${target_name}_PREFIX}/.venv/bin/activate &&
+
+      ${PIP_INSTALL_CMD} ${REQUIREMENTS_ARGS}
+
+      DEPENDS Python3::Python
+    )
+  else()
+    set(PIP_DOWNLOAD_CMD python -m pip download 
+                        --disable-pip-version-check 
+                        --exists-action i 
+                        -d ${SPHERAL_PIP_CACHE_DIR})
+
+    set(PIP_INSTALL_CMD env MPICC=${MPI_C_COMPILER} MPICXX=${MPI_CXX_COMPILER} CC=${CMAKE_C_COMPILER} CXX=${CMAKE_CXX_COMPILER} 
+                        python -m pip install 
+                        --disable-pip-version-check 
+                        --no-build-isolation 
+                        --no-index 
+                        -f ${SPHERAL_PIP_CACHE_DIR})
+
+    add_custom_target(${target_name} ALL
+      COMMAND ${Python3_EXECUTABLE} -m venv ${${target_name}_PREFIX}/.venv;
+      COMMAND . ${${target_name}_PREFIX}/.venv/bin/activate &&
+
+      ${PIP_DOWNLOAD_CMD} setuptools wheel cython poetry-core &&
+      ${PIP_INSTALL_CMD} setuptools wheel cython poetry-core &&
+
+      ${PIP_DOWNLOAD_CMD} ${REQUIREMENTS_ARGS} &&
+      ${PIP_INSTALL_CMD} ${REQUIREMENTS_ARGS}
+
+      DEPENDS Python3::Python
+    )
+  endif()
+
+  add_custom_target(clean_${target_name}
+    COMMAND rm -rf ${${target_name}_PREFIX}
   )
+
   set_property(TARGET ${target_name} PROPERTY EXECUTABLE python)
   set_property(TARGET ${target_name} PROPERTY ACTIVATE_VENV . ${${target_name}_PREFIX}/.venv/bin/activate)
 endfunction()
diff --git a/scripts/spheral-setup-venv.in b/scripts/spheral-setup-venv.in
index b0a7fe548..1ca7cfbae 100644
--- a/scripts/spheral-setup-venv.in
+++ b/scripts/spheral-setup-venv.in
@@ -7,11 +7,6 @@ cd @CMAKE_INSTALL_PREFIX@/.venv/@SPHERAL_SITE_PACKAGES_PATH@/Spheral
 cp --symbolic-link @CMAKE_INSTALL_PREFIX@/@SPHERAL_SITE_PACKAGES_PATH@/Spheral/* . > /dev/null 2>&1
 cd - > /dev/null 
 
-# We need to reconfigure ATS to use our virtual env python otherwise ats will not be able to launch properly.
-# echo "Reconfigure ATS executing python to virtual env python..."
-# sed -i '2s/.*/XXXXXX/' .venv/bin/ats
-# sed -i 's|XXXXXX|\x27\x27\x27exec\x27 @CMAKE_INSTALL_PREFIX@/.venv/bin/python "$0" "$@"|' .venv/bin/ats
-
 echo "Creating spheral symlink to spheral-env script ..."
 cd @CMAKE_INSTALL_PREFIX@
 chmod u+x scripts/spheral-env.sh