diff --git a/.github/workflows/continuous_integration.yml b/.github/workflows/continuous_integration.yml
index 418ea7a8..cb2b3395 100644
--- a/.github/workflows/continuous_integration.yml
+++ b/.github/workflows/continuous_integration.yml
@@ -29,7 +29,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        runner: ['navi3', 'vega20', 'mi200', 'mi300']
+        runner: ['navi3', 'vega20', 'mi200', 'mi300', 'rhel', 'sles']
         os: ['ubuntu-22.04']
         build-type: ['RelWithDebInfo']
         ci-flags: ['--linter clang-tidy']
@@ -45,6 +45,7 @@ jobs:
     - uses: actions/checkout@v4
 
     - name: Install requirements
+      if: ${{ !contains(matrix.runner, 'rhel') && !contains(matrix.runner, 'sles') }}
       timeout-minutes: 10
       shell: bash
       run: |
@@ -55,6 +56,13 @@ jobs:
         update-alternatives --install /usr/bin/gcc gcc /usr/bin/gcc-12 20 --slave /usr/bin/g++ g++ /usr/bin/g++-12 --slave /usr/bin/gcov gcov /usr/bin/gcov-12
         python3 -m pip install -r requirements.txt
 
+    - name: Install requirements For RHEL & SLES
+      if: ${{ contains(matrix.runner, 'rhel') || contains(matrix.runner, 'sles') }}
+      timeout-minutes: 10
+      shell: bash
+      run: |
+        python3 -m pip install -r requirements.txt
+
     - name: List Files
       shell: bash
       run: |
@@ -77,6 +85,7 @@ jobs:
           echo 'ROCPROFILER_PC_SAMPLING_BETA_ENABLED=1' >> $GITHUB_ENV
 
     - name: Configure, Build, and Test
+      if: ${{ !contains(matrix.runner, 'rhel') && !contains(matrix.runner, 'sles') }}
       timeout-minutes: 30
       shell: bash
       run:
@@ -98,6 +107,29 @@ jobs:
           --
           -LE "${EXCLUDED_TESTS}"
 
+    - name: Configure, Build, and Test
+      if: ${{ contains(matrix.runner, 'rhel') || contains(matrix.runner, 'sles') }}
+      timeout-minutes: 30
+      shell: bash
+      run:
+        sudo LD_LIBRARY_PATH=./build/lib:$LD_LIBRARY_PATH python3 ./source/scripts/run-ci.py -B build
+          --name ${{ github.repository }}-${{ github.ref_name }}-${{ matrix.runner }}-mi300-core
+          --build-jobs 16
+          --site $(echo $RUNNER_HOSTNAME)-$(/opt/rocm/bin/rocm_agent_enumerator | sed -n '2 p')
+          --gpu-targets ${{ env.GPU_TARGETS }}
+          --run-attempt ${{ github.run_attempt }}
+          --
+          -DROCPROFILER_DEP_ROCMCORE=ON
+          -DROCPROFILER_BUILD_DOCS=OFF
+          -DROCPROFILER_BUILD_CI=OFF
+          -DCMAKE_BUILD_TYPE=${{ matrix.build-type }}
+          -DCMAKE_INSTALL_PREFIX=/opt/rocprofiler-sdk
+          -DCPACK_GENERATOR='DEB;RPM;TGZ'
+          -DCPACK_PACKAGING_INSTALL_PREFIX="$(realpath /opt/rocm)"
+          -DPython3_EXECUTABLE=$(which python3)
+          --
+          -LE "${EXCLUDED_TESTS}"
+
     - name: Install
       if: ${{ contains(matrix.runner, env.CORE_EXT_RUNNER) }}
       timeout-minutes: 10