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FunctionDB.gps
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FunctionDB.gps
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Version=4.0.101
TotalKinetics=37
FunctionType=1
FunctionName=Mass action (reversible)
Description=k1 * PRODUCT <substrate_i> - k2 * PRODUCT <product_j>
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=-1
Usage=PRODUCTS
Low=1
High=-1
ParameterSize=4
FunctionParameter=k1
DataType=1
Usage=PARAMETER
FunctionParameter=substrate
DataType=3
Usage=SUBSTRATE
FunctionParameter=k2
DataType=1
Usage=PARAMETER
FunctionParameter=product
DataType=3
Usage=PRODUCT
UsageParameterSize=3
Usage=PARAMETER
Low=2
High=0
Usage=SUBSTRATE
Low=0
High=-1
Usage=PRODUCT
Low=0
High=-1
FunctionType=1
FunctionName=Mass action (irreversible)
Description=k1 * PRODUCT <substrate_i>
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=-1
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=2
FunctionParameter=k1
DataType=1
Usage=PARAMETER
FunctionParameter=substrate
DataType=3
Usage=SUBSTRATE
UsageParameterSize=2
Usage=PARAMETER
Low=1
High=0
Usage=SUBSTRATE
Low=0
High=-1
FunctionType=2
FunctionName=Constant flux (irreversible)
Description=v
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=0
High=-1
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=1
FunctionParameter=v
DataType=1
Usage=PARAMETER
UsageParameterSize=1
Usage=PARAMETER
Low=1
High=0
FunctionType=2
FunctionName=Constant flux (reversible)
Description=v
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=0
High=-1
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=1
FunctionParameter=v
DataType=1
Usage=PARAMETER
UsageParameterSize=1
Usage=PARAMETER
Low=1
High=0
FunctionType=2
FunctionName=Henri-Michaelis-Menten (irreversible)
Description=V*substrate/(Km+substrate)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=3
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
UsageParameterSize=2
Usage=SUBSTRATE
Low=1
High=0
Usage=PARAMETER
Low=2
High=0
FunctionType=2
FunctionName=Reversible Michaelis-Menten
Description=(Vf*substrate/Kms-Vr*product/Kmp)/(1+substrate/Kms+product/Kmp)
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=6
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=PARAMETER
Low=4
High=0
FunctionType=2
FunctionName=Substrate inhibition (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)/(1+substrate/Kms+product/Kmp+(substrate/Ki)^2)
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=7
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Substrate inhibition (irr)
Description=V*substrate/(Km+substrate+Km*(substrate/Ki)^2)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=4
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=2
Usage=SUBSTRATE
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Substrate activation (irr)
Description=V*(substrate/Ksa)^2/(1+substrate/Ksc+substrate/Ksa+(substrate/Ksa)^2)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=4
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ksc
DataType=1
Usage=PARAMETER
FunctionParameter=Ksa
DataType=1
Usage=PARAMETER
UsageParameterSize=2
Usage=SUBSTRATE
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Competitive inhibition (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)/(1+substrate/Kms+product/Kmp+Inhibitor/Ki)
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=8
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Competitive inhibition (irr)
Description=V*substrate/(Km+substrate+Km*Inhibitor/Ki)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=5
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Uncompetitive inhibition (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)/(1+(substrate/Kms+product/Kmp)*(1+Inhibitor/Ki))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=8
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Uncompetitive inhibition (irr)
Description=V*substrate/(Km+substrate*(1+Inhibitor/Ki))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=5
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Noncompetitive inhibition (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)/((1+substrate/Kms+product/Kmp)*(1+Inhibitor/Ki))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=8
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Noncompetitive inhibition (irr)
Description=V*substrate/((Km+substrate)*(1+Inhibitor/Ki))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=5
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ki
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Mixed inhibition (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)/(1+Inhibitor/Kis+(substrate/Kms+product/Kmp)*(1+Inhibitor/Kic))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=9
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Kis
DataType=1
Usage=PARAMETER
FunctionParameter=Kic
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=6
High=0
FunctionType=2
FunctionName=Mixed inhibition (irr)
Description=V*substrate/(Km*(1+Inhibitor/Kis)+substrate*(1+Inhibitor/Kic))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=6
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Inhibitor
DataType=1
Usage=MODIFIER
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Kis
DataType=1
Usage=PARAMETER
FunctionParameter=Kic
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=4
High=0
FunctionType=2
FunctionName=Specific activation (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)*Activator/(Ka+(1+substrate/Kms+product/Kmp)*Activator)
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=8
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ka
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Specific activation (irrev)
Description=V*substrate*Activator/(Kms*Ka+(Kms+substrate)*Activator)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=5
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ka
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Catalytic activation (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)*Activator/((1+substrate/Kms+product/Kmp)*(Ka+Activator))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=8
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Ka
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Catalytic activation (irrev)
Description=V*substrate*Activator/((Kms+substrate)*(Ka+Activator))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=5
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Ka
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=3
High=0
FunctionType=2
FunctionName=Mixed activation (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)*Activator/(Kas+Activator+(substrate/Kms+product/Kmp)*(Kac+Activator))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=9
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Kas
DataType=1
Usage=PARAMETER
FunctionParameter=Kac
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=6
High=0
FunctionType=2
FunctionName=Mixed activation (irrev)
Description=V*substrate*Activator/(Kms*(Kas+Activator)+substrate*(Kac+Activator))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=6
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Activator
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Kas
DataType=1
Usage=PARAMETER
FunctionParameter=Kac
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=4
High=0
FunctionType=2
FunctionName=Hyperbolic modifier (irrev)
Description=V*substrate*(1+b*Modifier/(a*Kd))/(Km*(1+Modifier/Kd)+substrate*(1+Modifier/(a*Kd)))
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=7
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Modifier
DataType=1
Usage=MODIFIER
FunctionParameter=Km
DataType=1
Usage=PARAMETER
FunctionParameter=V
DataType=1
Usage=PARAMETER
FunctionParameter=Kd
DataType=1
Usage=PARAMETER
FunctionParameter=a
DataType=1
Usage=PARAMETER
FunctionParameter=b
DataType=1
Usage=PARAMETER
UsageParameterSize=3
Usage=SUBSTRATE
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=5
High=0
FunctionType=2
FunctionName=Hyperbolic modifier (rev)
Description=(Vf*substrate/Kms-Vr*product/Kmp)*(1+b*Modifier/(a*Kd))/(1+Modifier/Kd+(substrate/Kms+product/Kmp)*(1+Modifier/(a*Kd)))
Reversible=1
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=1
High=0
ParameterSize=10
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=product
DataType=1
Usage=PRODUCT
FunctionParameter=Modifier
DataType=1
Usage=MODIFIER
FunctionParameter=Kms
DataType=1
Usage=PARAMETER
FunctionParameter=Kmp
DataType=1
Usage=PARAMETER
FunctionParameter=Vf
DataType=1
Usage=PARAMETER
FunctionParameter=Vr
DataType=1
Usage=PARAMETER
FunctionParameter=Kd
DataType=1
Usage=PARAMETER
FunctionParameter=a
DataType=1
Usage=PARAMETER
FunctionParameter=b
DataType=1
Usage=PARAMETER
UsageParameterSize=4
Usage=SUBSTRATE
Low=1
High=0
Usage=PRODUCT
Low=1
High=0
Usage=MODIFIER
Low=1
High=0
Usage=PARAMETER
Low=7
High=0
FunctionType=2
FunctionName=Allosteric inhibition (MWC)
Description=V*substrate*(Ks+substrate)^(n-1)/(L*(Ks*(1+Inhibitor/Ki))^n+(Ks+substrate)^n)
Reversible=0
UsageDescriptionSize=2
Usage=SUBSTRATES
Low=1
High=0
Usage=PRODUCTS
Low=0
High=-1
ParameterSize=7
FunctionParameter=substrate
DataType=1
Usage=SUBSTRATE
FunctionParameter=Inhibitor