diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index 774fa1442..fd6a427c7 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3555,7 +3555,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2012.05.01 AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000014 "germline stem cell") AnnotationAssertion(rdfs:label obo:CL_0000014 "germ line stem cell") EquivalentClasses(obo:CL_0000014 ObjectIntersectionOf(obo:CL_0000039 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000014 obo:CL_0000034) # Class: obo:CL_0000015 (male germ cell) @@ -3566,7 +3565,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "VHOG:0001531") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000015 "ncithesaurus:Spermatogenic_Cell") AnnotationAssertion(rdfs:label obo:CL_0000015 "male germ cell") AnnotationAssertion(rdfs:seeAlso obo:CL_0000015 "https://github.com/obophenotype/cell-ontology/issues/574") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000015 obo:CL_0000586) SubClassOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0007283)) # Class: obo:CL_0000016 (male germ line stem cell) @@ -3613,7 +3611,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "sperm cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "spermatozoid") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000019 "spermatozoon") AnnotationAssertion(rdfs:label obo:CL_0000019 "sperm") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000019 obo:CL_0000408) SubClassOf(obo:CL_0000019 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000018)) # Class: obo:CL_0000020 (spermatogonium) @@ -3635,15 +3632,12 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000021 "VHOG:0001530") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000021 "ncithesaurus:Egg") AnnotationAssertion(rdfs:label obo:CL_0000021 "female germ cell") EquivalentClasses(obo:CL_0000021 ObjectIntersectionOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048477))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000021 obo:CL_0000586) # Class: obo:CL_0000022 (female germ line stem cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1016/j.stem.2012.05.016") obo:IAO_0000115 obo:CL_0000022 "A stem cell that is the precursor of female gametes.") AnnotationAssertion(rdfs:label obo:CL_0000022 "female germ line stem cell") EquivalentClasses(obo:CL_0000022 ObjectIntersectionOf(obo:CL_0000021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0017145))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000022 obo:CL_0000014) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000022 obo:CL_0000021) # Class: obo:CL_0000023 (oocyte) @@ -3655,7 +3649,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "MESH:D009865") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000023 "WBbt:0006797") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000023 "oogonium") AnnotationAssertion(rdfs:label obo:CL_0000023 "oocyte") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000023 obo:CL_0000021) SubClassOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0007143)) SubClassOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_33208)) @@ -3665,7 +3658,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000024 "FMA:83673") AnnotationAssertion(rdfs:label obo:CL_0000024 "oogonial cell") EquivalentClasses(obo:CL_0000024 ObjectIntersectionOf(obo:CL_0000021 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0000278))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000024 obo:CL_0000021) SubClassOf(obo:CL_0000024 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000670)) # Class: obo:CL_0000025 (egg cell) @@ -3680,7 +3672,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000025 "mature oocyte") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000025 "ovum") AnnotationAssertion(rdfs:label obo:CL_0000025 "egg cell") AnnotationAssertion(foaf:depiction obo:CL_0000025 "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000025 obo:CL_0000675) SubClassOf(obo:CL_0000025 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0007143)) SubClassOf(obo:CL_0000025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000023)) @@ -3699,7 +3690,6 @@ SubClassOf(obo:CL_0000026 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000722)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0001-5208-3432") obo:IAO_0000115 obo:CL_0000027 "A smooth muscle cell derived from the neural crest.") AnnotationAssertion(rdfs:label obo:CL_0000027 "smooth muscle cell neural crest derived") EquivalentClasses(obo:CL_0000027 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000027 obo:CL_0000192) SubClassOf(obo:CL_0000027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000008)) # Class: obo:CL_0000028 (CNS neuron (sensu Nematoda and Protostomia)) @@ -3714,7 +3704,6 @@ SubClassOf(obo:CL_0000028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000338)) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000029 "neuron neural crest derived") AnnotationAssertion(rdfs:label obo:CL_0000029 "neural crest derived neuron") EquivalentClasses(obo:CL_0000029 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000029 obo:CL_0000540) SubClassOf(obo:CL_0000029 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002676)) # Class: obo:CL_0000030 (glioblast) @@ -3790,7 +3779,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000037 "colony forming un AnnotationAssertion(rdfs:comment obo:CL_0000037 "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.") AnnotationAssertion(rdfs:label obo:CL_0000037 "hematopoietic stem cell") EquivalentClasses(obo:CL_0000037 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002244) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048103))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000037 obo:CL_0000988) SubClassOf(obo:CL_0000037 obo:CL_0008001) SubClassOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000566)) @@ -3806,7 +3794,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "colony forming un AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000038 "erythroid stem cell") AnnotationAssertion(rdfs:label obo:CL_0000038 "erythroid progenitor cell") SubClassOf(obo:CL_0000038 obo:CL_0000764) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000038 obo:CL_0000839) SubClassOf(obo:CL_0000038 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050)) # Class: obo:CL_0000039 (germ line cell) @@ -3830,7 +3817,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000040 "monocyte stem cel AnnotationAssertion(rdfs:comment obo:CL_0000040 "Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label obo:CL_0000040 "monoblast") EquivalentClasses(obo:CL_0000040 ObjectIntersectionOf(obo:CL_0002194 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000791) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005730) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000040 obo:CL_0002194) SubClassOf(obo:CL_0000040 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002009)) # Class: obo:CL_0000041 (mature eosinophil) @@ -3845,7 +3831,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000041 "mature eosinophil l AnnotationAssertion(rdfs:comment obo:CL_0000041 "Eosinophils are CD125-positive (IL-5R), GM-CSFR-positive, IL-3R-positive, VLA4-positive. They can also express MHC Class I & II, CD4, CD9, CD11a, CD11b, CD11c, CD13, CD15, CD16, CD17, CD18, CD24, CD25,CD28, CD29, CD32, CD33, CD35, CD37, CD39, CD43, CD44, CD45, CD45RB, CD45RO, CD46, CD47, CD48, CD49d, CD49f, CD50, CD52, CD53, CD54, CD55, CD58, CD59, CD62L, CD63, CD65, CD66, CD69, CD71, CD76, CD80, CD81, CD82, CD86, CD87, CD88, CD89, CD92, CD95, CD97, CD98, CD99, CD100, CD101, CD116, CD117, CD119, CD120, CD123, CD124, CD125, CD131, CD137, CD139, CD148, CD149, CD151, CD153, CD156, CD162, CD161, CD162, CD165, CD174, CD182, CD183, CD191, CD192, CD193, CD196, CD213, IL9R, ad integrin, beta-7 integrin, FceRI, IL13Ra1, TGFbR, PAFR, LTB4R, C3aR, CystLT1R, CystLT2R, fMLPR, CRTH2 (PGD2 receptor), histamine 4R, IDO, KYN, PAR-2, Siglec-8, Siglec-10, LIR1, LIR2, LIR3, LIR7, TLR7, TLR8, and VLA-4. Eosinophils can also secrete CXCL1, eotaxin-1, GM-CSF, IL-2, IL-3, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-16, IL-18, IFN-gamma, LTC4, MIP-1alpha, NGF, PAF, RANTES, substance P, TGF-alpha, TGF-beta, TNF-alpha, and VIP.") AnnotationAssertion(rdfs:label obo:CL_0000041 "mature eosinophil") EquivalentClasses(obo:CL_0000041 ObjectIntersectionOf(obo:CL_0000771 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007152) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014046) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014047) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000022006) ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009129) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002495) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002540) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045730))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000041 obo:CL_0000771) SubClassOf(obo:CL_0000041 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000774)) # Class: obo:CL_0000042 (neutrophilic myeloblast) @@ -3855,7 +3840,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000042 "neutrophilic gran AnnotationAssertion(rdfs:comment obo:CL_0000042 "These cells are CD11b-negative, CD15-negative, CD16-negative, CD35-negative, CD49d-positive, CD68-positive, lactotransferrin-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.") AnnotationAssertion(rdfs:label obo:CL_0000042 "neutrophilic myeloblast") EquivalentClasses(obo:CL_0000042 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010799) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014362) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000042 obo:CL_0000835) SubClassOf(obo:CL_0000042 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000834)) # Class: obo:CL_0000043 (mature basophil) @@ -3870,7 +3854,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000043 "mature basophil leu AnnotationAssertion(rdfs:comment obo:CL_0000043 "Mature basophils are also capable of producing IL-3, IL-5, IL-6, IL-8, IL-13, IL-25, CCL22, tslp, vegf, and LTC4.") AnnotationAssertion(rdfs:label obo:CL_0000043 "mature basophil") EquivalentClasses(obo:CL_0000043 ObjectIntersectionOf(obo:CL_0000767 ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002349) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002351) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032616) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048295))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000043 obo:CL_0000767) SubClassOf(obo:CL_0000043 obo:CL_0002274) SubClassOf(obo:CL_0000043 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000770)) @@ -3931,7 +3914,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:ha AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0878932437") oboInOwl:hasRelatedSynonym obo:CL_0000049 "pluripotent stem cell (bone marrow)") AnnotationAssertion(rdfs:comment obo:CL_0000049 "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059).") AnnotationAssertion(rdfs:label obo:CL_0000049 "common myeloid progenitor") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000049 obo:CL_0002032) DisjointClasses(obo:CL_0000049 obo:CL_0000050) DisjointClasses(obo:CL_0000049 obo:CL_0000051) DisjointClasses(obo:CL_0000049 obo:CL_0000557) @@ -3949,7 +3931,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000050 "megakaryocyte/eryth AnnotationAssertion(rdfs:comment obo:CL_0000050 "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.") AnnotationAssertion(rdfs:label obo:CL_0000050 "megakaryocyte-erythroid progenitor cell") EquivalentClasses(obo:CL_0000050 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030218) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030219))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000050 obo:CL_0002032) SubClassOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049)) DisjointClasses(obo:CL_0000050 obo:CL_0000557) DisjointClasses(obo:CL_0000050 obo:CL_0002009) @@ -3969,7 +3950,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000051 "lymphopoietic ste AnnotationAssertion(rdfs:comment obo:CL_0000051 "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.") AnnotationAssertion(rdfs:label obo:CL_0000051 "common lymphoid progenitor") EquivalentClasses(obo:CL_0000051 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000051 obo:CL_0002032) # Class: obo:CL_0000052 (totipotent stem cell) @@ -4239,7 +4219,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000081 "FMA:62844") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000081 "MESH:D001773") AnnotationAssertion(rdfs:label obo:CL_0000081 "blood cell") EquivalentClasses(obo:CL_0000081 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000081 obo:CL_0000988) # Class: obo:CL_0000082 (epithelial cell of lung) @@ -4275,7 +4254,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000084 "immature T cell") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000084 "mature T cell") AnnotationAssertion(rdfs:label obo:CL_0000084 "T cell") EquivalentClasses(obo:CL_0000084 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002456))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000084 obo:CL_0000542) SubClassOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000827)) DisjointClasses(obo:CL_0000084 obo:CL_0000945) @@ -4341,7 +4319,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000091 "von Kupffer cell") AnnotationAssertion(rdfs:comment obo:CL_0000091 "Markers: Mouse: F4/80+, CD11b-low, CD68+, sialoadhesin+, CD163/SRCR+; role or process: immune, antigen-presentation, clearance of senescent erythrocytes, iron metabolism. Kupffer cells are also reportedly C3aR-positive, CD14-low, CD54-positive, CD88-positive, and CD284-positive. They are also capable of producing IL-1, IL-6, TNF-alpha, nitric oxide, PGD2, PGE2, PGF2alpha, and TXA2.") AnnotationAssertion(rdfs:label obo:CL_0000091 "Kupffer cell") EquivalentClasses(obo:CL_0000091 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001281) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000091 obo:CL_0000864) # Class: obo:CL_0000092 (osteoclast) @@ -4355,8 +4332,6 @@ AnnotationAssertion(rdfs:comment obo:CL_0000092 "Morphology: Highly vesicular; m AnnotationAssertion(rdfs:label obo:CL_0000092 "osteoclast") EquivalentClasses(obo:CL_0000092 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001474) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001850) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001937) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007597) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000011178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001954) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045453))) SubClassOf(obo:CL_0000092 obo:CL_0000518) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0000766) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0001035) SubClassOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576)) # Class: obo:CL_0000093 (obsolete osteochondroclast) @@ -4378,7 +4353,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000094 "granular leukocyte" AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000094 "polymorphonuclear leukocyte") AnnotationAssertion(rdfs:label obo:CL_0000094 "granulocyte") EquivalentClasses(obo:CL_0000094 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030141) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001332) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001969) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000094 obo:CL_0000766) # Class: obo:CL_0000095 (neuron associated cell) @@ -4405,7 +4379,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000096 "polynuclear neutrop AnnotationAssertion(rdfs:comment obo:CL_0000096 "Neutrophils are also capable of secreting GRO-alpha, IL-1beta, IL-1ra, IL-3, IL-12, IP-10, MIG, MIP-1alpha, MIP-1beta, TGF-beta, TNF-alpha, VEGF, and anti-microbial peptides. They can positively influence the chemotaxis of basophils, T-cells, monocytes, macrophages, dendritic cells, and other neutrophils. Neutrophils are also CD35-positive, CD64-positive, CD89-positive, CD184-positive, and fMLP receptor-positive Ly-6G-positive (mouse), TLR2-low, TLR4-low, and lineage-negative (CD2, CD3, CD5, CD9, CD19, CD36, CD49d, CD56, CD61, CD235a (glycophorin-A)).") AnnotationAssertion(rdfs:label obo:CL_0000096 "mature neutrophil") EquivalentClasses(obo:CL_0000096 ObjectIntersectionOf(obo:CL_0000775 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017500) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:BFO_0000051 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001979))) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010799) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001256) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001257) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001944) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000007597) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002536) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002690) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032637))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000096 obo:CL_0000775) # Class: obo:CL_0000097 (mast cell) @@ -4420,7 +4393,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:068340007X") oboInOwl:ha AnnotationAssertion(rdfs:comment obo:CL_0000097 "Mast cells are generally integrin beta-7-negative and positive for TLR2, TLR3, TLR4, TLR5, TLR7, TLR9, C3aR, C5aR, CR3, CR4, VEGF, FGF2, and renin. They can express MHC Class I and II on their surface. Activated murine mast cells (IgE+Antigen) were capable of expressing the following co-stimulatory molecules: CD95 (Fas), CD120b, CD137 (4-1BB), CD153 (CD30L), CD154 (CD40L), GITR, ICOSL, OX40L, PD-L1, and PD-L2. Note that there was some mouse strain variation. Mast cells have also been demonstrated to produce bFGF, CCL2, CCL4, CCL5, CCL11, CCL20, CXCL2, CXCL8, CXCL10, GM-CSF, IFN-gamma, IL-1, IL-2, IL-3, IL-8, IL-10, IL-11, IL-12, IL-13, IL-16, IL-25, IL-18, MIP-1, prostaglandin D2, SCF, TGF-beta, TNF-alpha, TSLP, VEGF, and XCL1. They express the transcription factors Transcription factors AP-1, GATA1, MITF, Notch2, PIAS3, PU.1, and STAT5.") AnnotationAssertion(rdfs:label obo:CL_0000097 "mast cell") EquivalentClasses(obo:CL_0000097 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0030141) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006169) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002349) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002539) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002660) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002690) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030210) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000097 obo:CL_0000766) SubClassOf(obo:CL_0000097 obo:CL_0002274) SubClassOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000831)) @@ -4555,7 +4527,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000113 "BTO:0001433") AnnotationAssertion(rdfs:label obo:CL_0000113 "mononuclear phagocyte") EquivalentClasses(obo:CL_0000113 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000113 obo:CL_0000518) SubClassOf(obo:CL_0000113 obo:CL_0000842) # Class: obo:CL_0000114 (surface ectodermal cell) @@ -4700,7 +4671,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8734446") oboInOwl:hasEx AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000128 "oligodendroglia") AnnotationAssertion(rdfs:comment obo:CL_0000128 "Oligodendrocytes are reportedly MDP-positive and CD4-negative.") AnnotationAssertion(rdfs:label obo:CL_0000128 "oligodendrocyte") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000128 obo:CL_0000126) SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017)) SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0043209)) SubClassOf(obo:CL_0000128 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002453)) @@ -4775,7 +4745,6 @@ AnnotationAssertion(rdfs:comment obo:CL_0000134 "Many but not all mesenchymal ce AnnotationAssertion(rdfs:label obo:CL_0000134 "mesenchymal stem cell") AnnotationAssertion(rdfs:seeAlso obo:CL_0000134 "https://github.com/obophenotype/cell-ontology/issues/474") SubClassOf(obo:CL_0000134 obo:CL_0000048) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000134 obo:CL_0002320) # Class: obo:CL_0000135 (fibrocyte) @@ -4784,7 +4753,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000135 "FMA:63879") AnnotationAssertion(rdfs:comment obo:CL_0000135 "Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A.") AnnotationAssertion(rdfs:label obo:CL_0000135 "fibrocyte") EquivalentClasses(obo:CL_0000135 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002495) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045766))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000135 obo:CL_0000499) SubClassOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000057)) # Class: obo:CL_0000136 (adipocyte) @@ -4983,7 +4951,6 @@ AnnotationAssertion(owl:deprecated obo:CL_0000156 "true"^^xsd:boolean) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721662544") obo:IAO_0000115 obo:CL_0000157 "A cell that specializes in secretion of surfactant in the alveoli of the lung.") AnnotationAssertion(rdfs:label obo:CL_0000157 "surfactant secreting cell") EquivalentClasses(obo:CL_0000157 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043129))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000157 obo:CL_0000151) # Class: obo:CL_0000158 (club cell) @@ -5111,8 +5078,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MA:0002419") oboInOwl:hasRela AnnotationAssertion(rdfs:comment obo:CL_0000169 "Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.") AnnotationAssertion(rdfs:label obo:CL_0000169 "type B pancreatic cell") EquivalentClasses(obo:CL_0000169 ObjectIntersectionOf(obo:CL_0000164 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000006) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030073))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000169 obo:CL_0000164) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000169 obo:CL_0000168) SubClassOf(obo:CL_0000169 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002351)) # Class: obo:CL_0000170 (glucagon secreting cell) @@ -5465,7 +5430,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000210 "FMA:86740") AnnotationAssertion(rdfs:label obo:CL_0000210 "photoreceptor cell") AnnotationAssertion(foaf:depiction obo:CL_0000210 "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) EquivalentClasses(obo:CL_0000210 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050962))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000210 obo:CL_0000006) # Class: obo:CL_0000211 (electrically active cell) @@ -5493,7 +5457,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000214 "CALOHA:TS-0995") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000214 "synoviocyte") AnnotationAssertion(rdfs:label obo:CL_0000214 "synovial cell") SubClassOf(obo:CL_0000214 obo:CL_0000213) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000214 obo:CL_0002078) SubClassOf(obo:CL_0000214 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002217)) # Class: obo:CL_0000215 (barrier cell) @@ -5513,7 +5476,6 @@ AnnotationAssertion(rdfs:label obo:CL_0000216 "Sertoli cell") EquivalentClasses(obo:CL_0000216 ObjectIntersectionOf(obo:CL_0000630 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001343))) SubClassOf(obo:CL_0000216 obo:CL_0000215) SubClassOf(obo:CL_0000216 obo:CL_0000511) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000216 obo:CL_0000630) SubClassOf(obo:CL_0000216 obo:CL_0002625) # Class: obo:CL_0000217 (insulating cell) @@ -5650,7 +5612,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000232 "RBC") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000232 "red blood cell") AnnotationAssertion(rdfs:label obo:CL_0000232 "erythrocyte") EquivalentClasses(obo:CL_0000232 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005840) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002039) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0008015) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015671))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000232 obo:CL_0000764) SubClassOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000558)) # Class: obo:CL_0000233 (platelet) @@ -5665,7 +5626,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000233 "enucleate thrombocy AnnotationAssertion(rdfs:comment obo:CL_0000233 "Platelets are reportedly CCR1-positive, CCR2-negative, CCR3-positive, CCR4-positive, CCR5-negative, CCR6-negative, CCR7-negative, CCR8-negative, CCR9-negative, CCR10-negative, CD16-positive, CD23-positive, CD32-positive, CD40-positive, CD41-positive CD42-positive, CD61-positive, CD62P-positive, CD64-positive, CD89-positive, CD102-positive, CD147-positive (activated platelets), CD154-positive (activated platelets), CD162-positive, CD209, CD282-positive, CD284-positive, CD289-positive, CD181-negative, CD182-negative, CD183-negative, CD184-positive, CLEC2-positive, GPVI-positive, JAMC-positive, PAR1-positive, PAR2-negative, PAR3-positive, PAR4-positive, TSP1-positive, and TXA2R-positive. Platelets can reportedly produce CCL2, CCL3, CCL5, CCL7, CCL17, CD40L, CXCL1, CXCL4, CXCL4L1, CXCL5, CXCL7, CXCL8, CXCL12, EGF, factor V, factor VII, factor XI, factor XIII, bFGF, histamine, IGF-1, IL-1beta, PAI-1, PDGF, plasminogen, protein S, serotonin, TGF-beta, TFPI, VEGF, and vWF.") AnnotationAssertion(rdfs:label obo:CL_0000233 "platelet") SubClassOf(obo:CL_0000233 obo:CL_0000081) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000233 obo:CL_0000763) SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405)) SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001874)) SubClassOf(obo:CL_0000233 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000556)) @@ -5697,7 +5657,6 @@ AnnotationAssertion(rdfs:comment obo:CL_0000235 "Morphology: Diameter 30_M-80 _M AnnotationAssertion(rdfs:label obo:CL_0000235 "macrophage") EquivalentClasses(obo:CL_0000235 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031268))) SubClassOf(obo:CL_0000235 obo:CL_0000113) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000235 obo:CL_0000766) SubClassOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576)) # Class: obo:CL_0000236 (B cell) @@ -5713,7 +5672,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000236 "B-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000236 "B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000236 "B cell") EquivalentClasses(obo:CL_0000236 ObjectIntersectionOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019724))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000236 obo:CL_0000945) SubClassOf(obo:CL_0000236 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826)) # Class: obo:CL_0000237 (keratinizing barrier epithelial cell) @@ -6153,7 +6111,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000300 "haploid nucleated c AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000300 "haploid germ cell") AnnotationAssertion(rdfs:label obo:CL_0000300 "gamete") EquivalentClasses(obo:CL_0000300 ObjectIntersectionOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009566))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000300 obo:CL_0000586) # Class: obo:CL_0000301 (pole cell) @@ -6203,7 +6160,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000307 "tracheocyte") AnnotationAssertion(rdfs:comment obo:CL_0000307 "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'") AnnotationAssertion(rdfs:label obo:CL_0000307 "tracheal epithelial cell") EquivalentClasses(obo:CL_0000307 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003126))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000307 obo:CL_0002202) SubClassOf(obo:CL_0000307 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000377)) # Class: obo:CL_0000308 (metal ion accumulating cell) @@ -6238,8 +6194,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000312 "malpighian cell") AnnotationAssertion(rdfs:comment obo:CL_0000312 "Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive.") AnnotationAssertion(rdfs:label obo:CL_0000312 "keratinocyte") EquivalentClasses(obo:CL_0000312 ObjectIntersectionOf(obo:CL_0000237 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001003))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000312 obo:CL_0000237) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000312 obo:CL_0000362) SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002775)) SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002776)) SubClassOf(obo:CL_0000312 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0090023)) @@ -6279,7 +6233,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D012629") obo:IAO_000011 AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000317 "sebocyte") AnnotationAssertion(rdfs:label obo:CL_0000317 "sebum secreting cell") EquivalentClasses(obo:CL_0000317 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001821))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000317 obo:CL_0000151) # Class: obo:CL_0000318 (sweat secreting cell) @@ -6421,8 +6374,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000336 "FMA:69262") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:69262") oboInOwl:hasExactSynonym obo:CL_0000336 "medullary chromaffin cell of adrenal gland") AnnotationAssertion(rdfs:label obo:CL_0000336 "adrenal medulla chromaffin cell") EquivalentClasses(obo:CL_0000336 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000336 obo:CL_0000150) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000336 obo:CL_0000166) SubClassOf(obo:CL_0000336 obo:CL_0000457) SubClassOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000011)) @@ -6477,7 +6428,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000343 "FMA:63846") AnnotationAssertion(rdfs:label obo:CL_0000343 "visual pigment cell (sensu Vertebrata)") EquivalentClasses(obo:CL_0000343 ObjectIntersectionOf(obo:CL_0000342 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050908))) SubClassOf(obo:CL_0000343 obo:CL_0000149) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000343 obo:CL_0000342) # Class: obo:CL_0000344 (obsolete non-visual cell (sensu Vertebrata)) @@ -6499,7 +6449,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000346 "Are these really all stem cells?") AnnotationAssertion(rdfs:label obo:CL_0000346 "hair follicle dermal papilla cell") EquivalentClasses(obo:CL_0000346 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000412))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000346 obo:CL_0000134) SubClassOf(obo:CL_0000346 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)) # Class: obo:CL_0000347 (scleral cell) @@ -6532,7 +6481,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000351 "FMA:83028") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000351 "trophoblastic cell") AnnotationAssertion(rdfs:label obo:CL_0000351 "trophoblast cell") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000351 obo:CL_0000349) SubClassOf(obo:CL_0000351 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000358)) # Class: obo:CL_0000352 (epiblast cell) @@ -6564,7 +6512,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000355 "FMA:86767") AnnotationAssertion(rdfs:comment obo:CL_0000355 "Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.") AnnotationAssertion(rdfs:label obo:CL_0000355 "multi-potent skeletal muscle stem cell") EquivalentClasses(obo:CL_0000355 ObjectIntersectionOf(obo:CL_0000048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001134))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000355 obo:CL_0000048) # Class: obo:CL_0000356 (hair matrix stem cell) @@ -6581,7 +6528,6 @@ SubClassOf(obo:CL_0000357 obo:CL_0000036) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:cjm") obo:IAO_0000115 obo:CL_0000358 "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.") AnnotationAssertion(rdfs:label obo:CL_0000358 "sphincter associated smooth muscle cell") EquivalentClasses(obo:CL_0000358 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004590))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000358 obo:CL_0000192) # Class: obo:CL_0000359 (vascular associated smooth muscle cell) @@ -6590,7 +6536,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000359 "VSMC") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000359 "vascular smooth muscle cell") AnnotationAssertion(rdfs:label obo:CL_0000359 "vascular associated smooth muscle cell") EquivalentClasses(obo:CL_0000359 ObjectIntersectionOf(obo:CL_0000192 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002049))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000359 obo:CL_0000192) SubClassOf(obo:CL_0000359 obo:CL_4033054) # Class: obo:CL_0000360 (morula cell) @@ -6801,7 +6746,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000388 "muscle attachment c AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000388 "tenocyte") AnnotationAssertion(rdfs:label obo:CL_0000388 "tendon cell") EquivalentClasses(obo:CL_0000388 ObjectIntersectionOf(obo:CL_0000135 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000043))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000388 obo:CL_0000135) SubClassOf(obo:CL_0000388 obo:CL_0000386) # Class: obo:CL_0000389 (socket cell (sensu Nematoda)) @@ -6861,7 +6805,6 @@ SubClassOf(obo:CL_0000396 obo:CL_0000387) AnnotationAssertion(rdfs:label obo:CL_0000397 "ganglion interneuron") EquivalentClasses(obo:CL_0000397 ObjectIntersectionOf(obo:CL_0000099 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0000045))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000397 obo:CL_0000099) # Class: obo:CL_0000398 (obsolete polygonal cell) @@ -6936,8 +6879,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000408 "BTO:0001277") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000408 "CALOHA:TS-0949") AnnotationAssertion(rdfs:label obo:CL_0000408 "male gamete") EquivalentClasses(obo:CL_0000408 ObjectIntersectionOf(obo:CL_0000015 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001375) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0009566))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000408 obo:CL_0000015) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000408 obo:CL_0000300) # Class: obo:CL_0000409 (obsolete scolopidial sheath cell) @@ -7266,7 +7207,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000451 "veiled cell") AnnotationAssertion(rdfs:label obo:CL_0000451 "dendritic cell") EquivalentClasses(obo:CL_0000451 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045580))) SubClassOf(obo:CL_0000451 obo:CL_0000113) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000451 obo:CL_0000738) DisjointClasses(obo:CL_0000451 obo:CL_0000542) # Class: obo:CL_0000452 (thyroid hormone secreting cell) @@ -7285,7 +7225,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000453 "LC") AnnotationAssertion(rdfs:comment obo:CL_0000453 "Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.") AnnotationAssertion(rdfs:label obo:CL_0000453 "Langerhans cell") EquivalentClasses(obo:CL_0000453 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001293) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002828))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000453 obo:CL_0000990) SubClassOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000763)) # Class: obo:CL_0000454 (epinephrine secreting cell) @@ -7515,7 +7454,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000484 "TC mast cells") AnnotationAssertion(rdfs:comment obo:CL_0000484 "They are CD88-positive. The cytoplasmic granules contain high levels of histamine and heparin (mouse) or major neutral proteases, tryptase, chymase, carboxypeptidase A, and cathepsin G (humans). Reportedly, they cannot produce leukotrienes (LTC4) and IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype.") AnnotationAssertion(rdfs:label obo:CL_0000484 "connective tissue type mast cell") EquivalentClasses(obo:CL_0000484 ObjectIntersectionOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002384))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000484 obo:CL_0000097) # Class: obo:CL_0000485 (mucosal type mast cell) @@ -7526,7 +7464,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000485 "T mast cells") AnnotationAssertion(rdfs:comment obo:CL_0000485 "They are CD88-negative. The cytoplasmic granules contain low levels of histamine and high levels of chondroitin sulfate (mouse) or major neutral proteases and tryptase (humans). Additionally, they can produce leukotrienes (LTC4), IL-5, IL-6, and low levels of IL-4. They are reportedly very heterogeneous depending upon location and can convert to the MC(T) phenotype.") AnnotationAssertion(rdfs:label obo:CL_0000485 "mucosal type mast cell") EquivalentClasses(obo:CL_0000485 ObjectIntersectionOf(obo:CL_0000097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001961) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002540))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000485 obo:CL_0000097) # Class: obo:CL_0000486 (garland cell) @@ -7581,7 +7518,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive helper AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000492 "CD4-positive helper T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000492 "CD4-positive helper T cell") EquivalentClasses(obo:CL_0000492 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000492 obo:CL_0000624) SubClassOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) SubClassOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217)) @@ -7721,7 +7657,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "BTO:0000993") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000510 "FMA:62897") AnnotationAssertion(rdfs:label obo:CL_0000510 "paneth cell") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000510 obo:CL_0000150) SubClassOf(obo:CL_0000510 obo:CL_0000323) SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001277)) SubClassOf(obo:CL_0000510 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001983)) @@ -7746,7 +7681,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000513 "cardiac muscle prog AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000513 "cardiomyocyte progenitor cell") AnnotationAssertion(rdfs:label obo:CL_0000513 "cardiac muscle myoblast") EquivalentClasses(obo:CL_0000513 ObjectIntersectionOf(obo:CL_0000056 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001133) ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000746))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000513 obo:CL_0000056) # Class: obo:CL_0000514 (smooth muscle myoblast) @@ -7975,7 +7909,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000542 "VHOG:0001535") AnnotationAssertion(rdfs:comment obo:CL_0000542 "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)") AnnotationAssertion(rdfs:label obo:CL_0000542 "lymphocyte") EquivalentClasses(obo:CL_0000542 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017500) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000542 obo:CL_0000738) SubClassOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051)) DisjointClasses(obo:CL_0000542 obo:CL_0000766) @@ -8009,7 +7942,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000545 "helper T cell type AnnotationAssertion(rdfs:comment obo:CL_0000545 "This cell type is compatible with the HIPC Lyoplate markers for 'Th1 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 1 T cells.") AnnotationAssertion(rdfs:label obo:CL_0000545 "T-helper 1 cell") EquivalentClasses(obo:CL_0000545 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001835) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000545 obo:CL_0000492) SubClassOf(obo:CL_0000545 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0000546 (T-helper 2 cell) @@ -8029,7 +7961,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000546 "helper T cell type AnnotationAssertion(rdfs:comment obo:CL_0000546 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Th1/Th17 CD4+ T cell' (see CL:0001051), but includes the additional necessary and sufficient conditions to allow classification as a T-helper 2 T cell.") AnnotationAssertion(rdfs:label obo:CL_0000546 "T-helper 2 cell") EquivalentClasses(obo:CL_0000546 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001941) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000546 obo:CL_0000492) SubClassOf(obo:CL_0000546 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0000547 (proerythroblast) @@ -8040,7 +7971,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:ha AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000547 "pronormoblast") AnnotationAssertion(rdfs:label obo:CL_0000547 "proerythroblast") EquivalentClasses(obo:CL_0000547 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000547 obo:CL_0000764) SubClassOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000038)) # Class: obo:CL_0000548 (obsolete animal cell) @@ -8064,7 +7994,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:ha AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000549 "prorubricyte") AnnotationAssertion(rdfs:label obo:CL_0000549 "basophilic erythroblast") EquivalentClasses(obo:CL_0000549 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000549 obo:CL_0000765) SubClassOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547)) # Class: obo:CL_0000550 (polychromatophilic erythroblast) @@ -8079,7 +8008,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:ha AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000550 "rubricyte") AnnotationAssertion(rdfs:label obo:CL_0000550 "polychromatophilic erythroblast") EquivalentClasses(obo:CL_0000550 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017504) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000550 obo:CL_0000765) SubClassOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000549)) # Class: obo:CL_0000551 (unimodal nocireceptor) @@ -8098,7 +8026,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:ha AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") oboInOwl:hasExactSynonym obo:CL_0000552 "pyknotic eto enrythroblast") AnnotationAssertion(rdfs:label obo:CL_0000552 "orthochromatic erythroblast") EquivalentClasses(obo:CL_0000552 ObjectIntersectionOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0030263))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000552 obo:CL_0000765) SubClassOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000550)) # Class: obo:CL_0000553 (megakaryocyte progenitor cell) @@ -8121,7 +8048,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000553 "promegakaryocyte" AnnotationAssertion(rdfs:comment obo:CL_0000553 "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.") AnnotationAssertion(rdfs:label obo:CL_0000553 "megakaryocyte progenitor cell") EquivalentClasses(obo:CL_0000553 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007113) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030219))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000553 obo:CL_0000839) SubClassOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050)) # Class: obo:CL_0000554 (gastrin stimulating hormone secreting cell) @@ -8146,7 +8072,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000556 "megalocaryocyte") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000556 "megalokaryocyte") AnnotationAssertion(rdfs:comment obo:CL_0000556 "Megakaryocytes are reportedly CD181-positive and CD182-positive.") AnnotationAssertion(rdfs:label obo:CL_0000556 "megakaryocyte") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000556 obo:CL_0000763) SubClassOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001393)) SubClassOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000553)) DisjointClasses(obo:CL_0000556 obo:CL_0000764) @@ -8164,7 +8089,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation( AnnotationAssertion(rdfs:comment obo:CL_0000557 "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.") AnnotationAssertion(rdfs:label obo:CL_0000557 "granulocyte monocyte progenitor cell") EquivalentClasses(obo:CL_0000557 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000007857) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000007858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030851))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000557 obo:CL_0002032) SubClassOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049)) # Class: obo:CL_0000558 (reticulocyte) @@ -8175,7 +8099,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000558 "CALOHA:TS-0864") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000558 "MESH:D012156") AnnotationAssertion(rdfs:label obo:CL_0000558 "reticulocyte") EquivalentClasses(obo:CL_0000558 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0071971))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000558 obo:CL_0000764) SubClassOf(obo:CL_0000558 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000552)) # Class: obo:CL_0000559 (promonocyte) @@ -8186,7 +8109,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000559 "FMA:83551") AnnotationAssertion(rdfs:comment obo:CL_0000559 "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label obo:CL_0000559 "promonocyte") EquivalentClasses(obo:CL_0000559 ObjectIntersectionOf(obo:CL_0002194 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000559 obo:CL_0002194) SubClassOf(obo:CL_0000559 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000040)) # Class: obo:CL_0000560 (band form neutrophil) @@ -8200,7 +8122,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000560 "rod neutrophil") AnnotationAssertion(rdfs:comment obo:CL_0000560 "Found in the Band 1 fraction.") AnnotationAssertion(rdfs:label obo:CL_0000560 "band form neutrophil") EquivalentClasses(obo:CL_0000560 ObjectIntersectionOf(obo:CL_0000096 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007597) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000010799) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009129) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000010543) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001337) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001580))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000560 obo:CL_0000096) SubClassOf(obo:CL_0000560 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000582)) # Class: obo:CL_0000561 (amacrine cell) @@ -8224,7 +8145,6 @@ AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000562 "RBC") AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000562 "red blood cell") AnnotationAssertion(rdfs:label obo:CL_0000562 "nucleate erythrocyte") EquivalentClasses(obo:CL_0000562 ObjectIntersectionOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000562 obo:CL_0000232) SubClassOf(obo:CL_0000562 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002421)) # Class: obo:CL_0000563 (endospore) @@ -8244,7 +8164,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000564 "neutrophilic progra AnnotationAssertion(rdfs:comment obo:CL_0000564 "These cells are CD11b-negative, CD15-positive, CD16-negative, CD49d-positive, CD68-positive, CD35-negative, and fMLP receptor-negative. They are found in the Band 3 fraction.") AnnotationAssertion(rdfs:label obo:CL_0000564 "neutrophilic promyelocyte") EquivalentClasses(obo:CL_0000564 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000014362) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000009978) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000564 obo:CL_0000836) SubClassOf(obo:CL_0000564 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000042)) # Class: obo:CL_0000565 (fat body cell) @@ -8261,7 +8180,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000566 "chondroplast") AnnotationAssertion(rdfs:comment obo:CL_0000566 "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.") AnnotationAssertion(rdfs:label obo:CL_0000566 "angioblastic mesenchymal cell") EquivalentClasses(obo:CL_0000566 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001444) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002112) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016043))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000566 obo:CL_0000134) SubClassOf(obo:CL_0000566 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000134)) # Class: obo:CL_0000567 (polymodal nocireceptor) @@ -8298,8 +8216,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExact AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:68653") oboInOwl:hasExactSynonym obo:CL_0000570 "thyroid parafollicular cell") AnnotationAssertion(rdfs:label obo:CL_0000570 "parafollicular cell") EquivalentClasses(obo:CL_0000570 ObjectIntersectionOf(obo:CL_0000710 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001024) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0014046) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036161))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000570 obo:CL_0000443) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000570 obo:CL_0000710) SubClassOf(obo:CL_0000570 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001747)) SubClassOf(obo:CL_0000570 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)) @@ -8355,7 +8271,6 @@ AnnotationAssertion(rdfs:comment obo:CL_0000576 "Morphology: Mononuclear cell, d AnnotationAssertion(rdfs:label obo:CL_0000576 "monocyte") EquivalentClasses(obo:CL_0000576 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030316) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011))) SubClassOf(obo:CL_0000576 obo:CL_0000113) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000576 obo:CL_0000766) SubClassOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000559)) # Class: obo:CL_0000577 (type EC enteroendocrine cell) @@ -8395,7 +8310,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000580 "FMA:83540") AnnotationAssertion(rdfs:comment obo:CL_0000580 "These cells are also CD15-positive, CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction.") AnnotationAssertion(rdfs:label obo:CL_0000580 "neutrophilic myelocyte") EquivalentClasses(obo:CL_0000580 ObjectIntersectionOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005310) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009725) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009978) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000580 obo:CL_0000776) SubClassOf(obo:CL_0000580 obo:CL_0002193) SubClassOf(obo:CL_0000580 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000564)) @@ -8407,7 +8321,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000581 "FMA:83025") AnnotationAssertion(rdfs:comment obo:CL_0000581 "Markers: Mouse: F4/80-high, CD11b-high, CD68+, SIGNR1+, Dectin-1+.") AnnotationAssertion(rdfs:label obo:CL_0000581 "peritoneal macrophage") EquivalentClasses(obo:CL_0000581 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001179) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001807) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006172) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002062))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000581 obo:CL_0000864) # Class: obo:CL_0000582 (neutrophilic metamyelocyte) @@ -8417,7 +8330,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000582 "juvenile neutrophil AnnotationAssertion(rdfs:comment obo:CL_0000582 "These cells are also CD35-negative, CD49d-positive, and fMLP receptor-negative. They are found in the Band 2 fraction.") AnnotationAssertion(rdfs:label obo:CL_0000582 "neutrophilic metamyelocyte") EquivalentClasses(obo:CL_0000582 ObjectIntersectionOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005310) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009725) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000009978) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000010543) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001580) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000582 obo:CL_0000776) SubClassOf(obo:CL_0000582 obo:CL_0002192) SubClassOf(obo:CL_0000582 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000580)) @@ -8432,7 +8344,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000583 "MF.Lu") AnnotationAssertion(rdfs:comment obo:CL_0000583 "Markers: Mouse: F4/80mid, CD11b-/low, CD11c+, CD68+, sialoadhesin+, dectin-1+, MR+, CX3CR1-.") AnnotationAssertion(rdfs:label obo:CL_0000583 "alveolar macrophage") EquivalentClasses(obo:CL_0000583 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001206) ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0002299) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001807) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000583 obo:CL_0000864) SubClassOf(obo:CL_0000583 obo:CL_1001603) # Class: obo:CL_0000584 (enterocyte) @@ -8463,7 +8374,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "NCIT:C12597") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "VHOG:0001534") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000586 "WBbt:0006796") AnnotationAssertion(rdfs:label obo:CL_0000586 "germ cell") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000586 obo:CL_0000039) SubClassOf(obo:CL_0000586 ObjectSomeValuesFrom(obo:RO_0002216 obo:GO_0009566)) # Class: obo:CL_0000587 (cold sensing thermoreceptor cell) @@ -8479,7 +8389,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000588 "BTO:0002516") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000588 "FMA:83027") AnnotationAssertion(rdfs:label obo:CL_0000588 "odontoclast") EquivalentClasses(obo:CL_0000588 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042483))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000588 obo:CL_0000092) # Class: obo:CL_0000589 (cochlear inner hair cell) @@ -8540,7 +8449,6 @@ AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000595 "red blood cell") AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000595 "RBC") AnnotationAssertion(rdfs:label obo:CL_0000595 "enucleate erythrocyte") EquivalentClasses(obo:CL_0000595 ObjectIntersectionOf(obo:CL_0000232 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001405))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000595 obo:CL_0000232) SubClassOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002422)) # Class: obo:CL_0000596 (sexual spore) @@ -8672,7 +8580,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000611 "eosinophil stem c AnnotationAssertion(rdfs:comment obo:CL_0000611 "These cells are CD34-positive, CD45RA-negative, CD71-negative, and lineage-negative (CD2, CD3 epsilon, CD4, CD5, CD8a, CD14, CD19, CD20, integrin alpha-M, NCAM-1, SCA-1, Ly6G, Ly76).") AnnotationAssertion(rdfs:label obo:CL_0000611 "eosinophil progenitor cell") EquivalentClasses(obo:CL_0000611 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000611 obo:CL_0002191) SubClassOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557)) # Class: obo:CL_0000612 (eosinophilic myelocyte) @@ -8682,7 +8589,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000612 "BTO:0003454") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000612 "FMA:83542") AnnotationAssertion(rdfs:label obo:CL_0000612 "eosinophilic myelocyte") EquivalentClasses(obo:CL_0000612 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000612 obo:CL_0000772) SubClassOf(obo:CL_0000612 obo:CL_0002193) # Class: obo:CL_0000613 (basophil progenitor cell) @@ -8695,7 +8601,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000613 "colony forming un AnnotationAssertion(rdfs:comment obo:CL_0000613 "BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf).") AnnotationAssertion(rdfs:label obo:CL_0000613 "basophil progenitor cell") EquivalentClasses(obo:CL_0000613 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000016401))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000613 obo:CL_0002191) SubClassOf(obo:CL_0000613 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002028)) # Class: obo:CL_0000614 (basophilic myelocyte) @@ -8705,7 +8610,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000614 "BTO:0003456") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000614 "FMA:83543") AnnotationAssertion(rdfs:label obo:CL_0000614 "basophilic myelocyte") EquivalentClasses(obo:CL_0000614 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0070820) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000614 obo:CL_0000768) SubClassOf(obo:CL_0000614 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000830)) # Class: obo:CL_0000615 (basidiospore) @@ -8795,7 +8699,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000624 "CD4-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000624 "CD4-positive, alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000624 "CD4-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000624 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000624 obo:CL_0000791) DisjointClasses(obo:CL_0000624 obo:CL_0000625) # Class: obo:CL_0000625 (CD8-positive, alpha-beta T cell) @@ -8806,7 +8709,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000625 "CD8-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000625 "CD8-positive, alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000625 "CD8-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000625 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000625 obo:CL_0000791) # Class: obo:CL_0000626 (olfactory granule cell) @@ -8873,7 +8775,6 @@ AnnotationAssertion(rdfs:label obo:CL_0000632 "hepatic stellate cell") EquivalentClasses(obo:CL_0000632 ObjectIntersectionOf(obo:CL_0002320 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002107) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000007939))) SubClassOf(obo:CL_0000632 obo:CL_0000057) SubClassOf(obo:CL_0000632 obo:CL_0000327) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000632 obo:CL_0002320) # Class: obo:CL_0000633 (Hensen cell) @@ -9020,7 +8921,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ISBN:0702022918") Annotation( AnnotationAssertion(rdfs:comment obo:CL_0000647 "Role or process: Chronic infection, granulomatous inflammation. Consider also megakaryocyte (CL:0000556) as sometimes multinucleated giant cell is used to refer to this.") AnnotationAssertion(rdfs:label obo:CL_0000647 "multinucleated giant cell") EquivalentClasses(obo:CL_0000647 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002432) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002544))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000647 obo:CL_0000766) SubClassOf(obo:CL_0000647 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000235)) # Class: obo:CL_0000648 (kidney granular cell) @@ -9099,7 +8999,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000654 "FMA:18645") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000654 "primary oogonium") AnnotationAssertion(rdfs:label obo:CL_0000654 "primary oocyte") EquivalentClasses(obo:CL_0000654 ObjectIntersectionOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0051321))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000654 obo:CL_0000023) SubClassOf(obo:CL_0000654 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000024)) # Class: obo:CL_0000655 (secondary oocyte) @@ -9110,7 +9009,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000655 "FMA:18646") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000655 "primary oogonium") AnnotationAssertion(rdfs:label obo:CL_0000655 "secondary oocyte") EquivalentClasses(obo:CL_0000655 ObjectIntersectionOf(obo:CL_0000023 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0007147))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000655 obo:CL_0000023) SubClassOf(obo:CL_0000655 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000654)) # Class: obo:CL_0000656 (primary spermatocyte) @@ -9233,8 +9131,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000670 "gonocyte") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000670 "primitive germ cell") AnnotationAssertion(rdfs:label obo:CL_0000670 "primordial germ cell") EquivalentClasses(obo:CL_0000670 ObjectIntersectionOf(obo:CL_0000039 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000922) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048870))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000670 obo:CL_0000039) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000670 obo:CL_0000219) # Class: obo:CL_0000671 (centripetally migrating follicle cell) @@ -9271,7 +9167,6 @@ SubClassOf(obo:CL_0000674 obo:CL_0000477) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000675 "A mature sexual reproductive cell of the female germline.") AnnotationAssertion(rdfs:label obo:CL_0000675 "female gamete") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000675 obo:CL_0000021) SubClassOf(obo:CL_0000675 obo:CL_0000300) # Class: obo:CL_0000676 (cap cell) @@ -9360,7 +9255,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo AnnotationAssertion(rdfs:label obo:CL_0000686 "cerebrospinal fluid secreting cell") EquivalentClasses(obo:CL_0000686 ObjectIntersectionOf(obo:CL_0000151 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0033326))) SubClassOf(obo:CL_0000686 obo:CL_0000075) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000686 obo:CL_0000151) SubClassOf(obo:CL_0000686 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000333)) # Class: obo:CL_0000687 (R1 photoreceptor cell) @@ -9534,8 +9428,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "JB:jb") obo:IAO_0000115 obo:C AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000708 "leptomemingeal cell") AnnotationAssertion(rdfs:label obo:CL_0000708 "leptomeningeal cell") EquivalentClasses(obo:CL_0000708 ObjectIntersectionOf(obo:CL_0000327 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003210))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000708 obo:CL_0000327) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000708 obo:CL_0002320) # Class: obo:CL_0000709 (R8 photoreceptor cell) @@ -9756,7 +9648,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000738 "white blood cell") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000738 "immune cell") AnnotationAssertion(rdfs:label obo:CL_0000738 "leukocyte") EquivalentClasses(obo:CL_0000738 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002505) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001667))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000738 obo:CL_0000988) SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002405)) SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_7742)) SubClassOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037)) @@ -9792,7 +9683,6 @@ SubClassOf(obo:CL_0000741 obo:CL_0008039) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15951842") obo:IAO_0000115 obo:CL_0000742 "A round chondrocyte that first differentiates in the late embryonic growth plate of bone.") AnnotationAssertion(rdfs:label obo:CL_0000742 "periarticular chondrocyte") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000742 obo:CL_0000138) SubClassOf(obo:CL_0000742 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0010996)) # Class: obo:CL_0000743 (hypertrophic chondrocyte) @@ -9979,7 +9869,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000762 "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals.") AnnotationAssertion(rdfs:label obo:CL_0000762 "nucleated thrombocyte") EquivalentClasses(obo:CL_0000762 ObjectIntersectionOf(obo:CL_0000763 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0007596))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000762 obo:CL_0000763) SubClassOf(obo:CL_0000762 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000828)) # Class: obo:CL_0000763 (myeloid cell) @@ -9990,7 +9879,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000763 "CALOHA:TS-0647") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000763 "MESH:D022423") AnnotationAssertion(rdfs:label obo:CL_0000763 "myeloid cell") EquivalentClasses(obo:CL_0000763 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000763 obo:CL_0000988) # Class: obo:CL_0000764 (erythroid lineage cell) @@ -10013,7 +9901,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000765 "MESH:D004900") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000765 "normoblast") AnnotationAssertion(rdfs:label obo:CL_0000765 "erythroblast") EquivalentClasses(obo:CL_0000765 ObjectIntersectionOf(obo:CL_0000764 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005634) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0005730) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030218))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000765 obo:CL_0000764) SubClassOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547)) # Class: obo:CL_0000766 (myeloid leukocyte) @@ -10021,7 +9908,6 @@ SubClassOf(obo:CL_0000765 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000547)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") obo:IAO_0000115 obo:CL_0000766 "A cell of the monocyte, granulocyte, or mast cell lineage.") AnnotationAssertion(rdfs:label obo:CL_0000766 "myeloid leukocyte") EquivalentClasses(obo:CL_0000766 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000049))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000766 obo:CL_0000738) # Class: obo:CL_0000767 (basophil) @@ -10036,7 +9922,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000767 "basophilic leukocyt AnnotationAssertion(rdfs:comment obo:CL_0000767 "Matures in the bone marrow and account for <1% of leukocytes in the peripheral blood, spleen, and bone marrow. Basophils are described as being CD11a-positive, CD11b-positive, CD13-positive, CD15-positive, CD18-positive, CD21-positive, CD25-positive, CD29-positive, CD35-positive, CD40-positive, CD40L-positive, CD44-positive, CD45R-negative, CD46-positive, CD49a-positive, CD49b-positive, CD49d-positive, CD55-positive, CD59-positive, CD62L-positive, CD63-positive, CD69-positive, CD90-negative, CD116-positive, CD117-negative, CD124-positive, CD125-positive, CD131-positive, CD161-positive, CD184-positive, CD191-positive, CD192-positive, CD197-positive, CD200R3-positive, CD218-positive, CD282-positive, CD284-positive, CD289-positive, CD290-positive, CD294-positive, natural killer cell receptor 2B4-positive, smad1-positive, CD3-negative, CD4-negative, CD7-negative, CD8-negative, CD14-negative, CD15-negative, CD16-negative, CD19-negative, CD20-negative, CD34-negative, CD36-negative, CD45R-negative, CD56-negative, CD57-negative, CD235a-negative, and GR1-negative. Transcription factors- GATA1-positive, PU.1-positive.") AnnotationAssertion(rdfs:label obo:CL_0000767 "basophil") EquivalentClasses(obo:CL_0000767 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001344) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001950) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000007431))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000767 obo:CL_0000094) # Class: obo:CL_0000768 (immature basophil) @@ -10045,7 +9930,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000768 "immature basophilic AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000768 "immature basophilic leukocyte") AnnotationAssertion(rdfs:label obo:CL_0000768 "immature basophil") EquivalentClasses(obo:CL_0000768 ObjectIntersectionOf(obo:CL_0000767 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000768 obo:CL_0000767) SubClassOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000830)) # Class: obo:CL_0000769 (basophilic metamyelocyte) @@ -10054,7 +9938,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000769 "FMA:84198") AnnotationAssertion(rdfs:label obo:CL_0000769 "basophilic metamyelocyte") EquivalentClasses(obo:CL_0000769 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000769 obo:CL_0000768) SubClassOf(obo:CL_0000769 obo:CL_0002192) SubClassOf(obo:CL_0000769 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000614)) @@ -10063,7 +9946,6 @@ SubClassOf(obo:CL_0000769 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000614)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:18466030") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000770 "A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil.") AnnotationAssertion(rdfs:label obo:CL_0000770 "band form basophil") EquivalentClasses(obo:CL_0000770 ObjectIntersectionOf(obo:CL_0000768 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000770 obo:CL_0000768) SubClassOf(obo:CL_0000770 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000769)) # Class: obo:CL_0000771 (eosinophil) @@ -10082,7 +9964,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000771 "eosinophilic leukoc AnnotationAssertion(rdfs:comment obo:CL_0000771 "Eosinophils are also CD14-negative, CD32-positive, CD44-positive, CD48-positive, CD69-positive, CD192-negative, MBP1-positive, MBP2-positive, TLR2-negative, TLR4-negative, and lineage-negative (B220, CD2, CD14, CD19, CD56, CD71, CD117, CD123, CD235a (glycophorin A), and TER119). The cytokines IL-3, IL-5, and GM-CSF are involved in their development and differentiation. Usually considered CD16-negative, CD16 is observed on eosinophilic metamyelocyte.") AnnotationAssertion(rdfs:label obo:CL_0000771 "eosinophil") EquivalentClasses(obo:CL_0000771 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001254) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001255) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000771 obo:CL_0000094) # Class: obo:CL_0000772 (immature eosinophil) @@ -10092,7 +9973,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000772 "immature eosinophil AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000772 "immature eosinophilic leukocyte") AnnotationAssertion(rdfs:label obo:CL_0000772 "immature eosinophil") EquivalentClasses(obo:CL_0000772 ObjectIntersectionOf(obo:CL_0000771 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000772 obo:CL_0000771) SubClassOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000833)) # Class: obo:CL_0000773 (eosinophilic metamyelocyte) @@ -10100,7 +9980,6 @@ SubClassOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000833)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:19622087") obo:IAO_0000115 obo:CL_0000773 "A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative.") AnnotationAssertion(rdfs:label obo:CL_0000773 "eosinophilic metamyelocyte") EquivalentClasses(obo:CL_0000773 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017502) ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017507) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000792) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042582) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0070820) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001456) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001892) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002031))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000773 obo:CL_0000772) SubClassOf(obo:CL_0000773 obo:CL_0002192) SubClassOf(obo:CL_0000773 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000612)) @@ -10109,7 +9988,6 @@ SubClassOf(obo:CL_0000773 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000612)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "PMID:19622087") Annotation(oboInOwl:hasDbXref "http://www.cap.org") obo:IAO_0000115 obo:CL_0000774 "A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil.") AnnotationAssertion(rdfs:label obo:CL_0000774 "band form eosinophil") EquivalentClasses(obo:CL_0000774 ObjectIntersectionOf(obo:CL_0000772 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017506))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000774 obo:CL_0000772) SubClassOf(obo:CL_0000774 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000773)) # Class: obo:CL_0000775 (neutrophil) @@ -10133,7 +10011,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophilic leucoc AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000775 "neutrophilic leukocyte") AnnotationAssertion(rdfs:label obo:CL_0000775 "neutrophil") EquivalentClasses(obo:CL_0000775 ObjectIntersectionOf(obo:CL_0000094 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001479) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000775 obo:CL_0000094) # Class: obo:CL_0000776 (immature neutrophil) @@ -10145,7 +10022,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrophil AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000776 "immature neutrophilic leucocyte") AnnotationAssertion(rdfs:label obo:CL_0000776 "immature neutrophil") EquivalentClasses(obo:CL_0000776 ObjectIntersectionOf(obo:CL_0000775 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017509))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000776 obo:CL_0000775) SubClassOf(obo:CL_0000776 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000564)) # Class: obo:CL_0000777 (mesangial phagocyte) @@ -10154,7 +10030,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0000777 "mesangial cell") AnnotationAssertion(rdfs:label obo:CL_0000777 "mesangial phagocyte") EquivalentClasses(obo:CL_0000777 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0002320) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048771))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000777 obo:CL_0000864) # Class: obo:CL_0000778 (mononuclear osteoclast) @@ -10162,7 +10037,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000778 "Morphology: mononuclear, highly vesicular.") AnnotationAssertion(rdfs:label obo:CL_0000778 "mononuclear osteoclast") EquivalentClasses(obo:CL_0000778 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000778 obo:CL_0000092) # Class: obo:CL_0000779 (multinuclear osteoclast) @@ -10171,7 +10045,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000779 "multinucleated oste AnnotationAssertion(rdfs:comment obo:CL_0000779 "Morphology: multinucleated, highly vesicular.") AnnotationAssertion(rdfs:label obo:CL_0000779 "multinuclear osteoclast") EquivalentClasses(obo:CL_0000779 ObjectIntersectionOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000779 obo:CL_0000092) SubClassOf(obo:CL_0000779 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000778)) # Class: obo:CL_0000780 (multinuclear odontoclast) @@ -10181,7 +10054,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000780 "multinucleated odon AnnotationAssertion(rdfs:comment obo:CL_0000780 "Morphology: multinucleated, highly vesicular; location: roots of deciduous (milk) teeth.") AnnotationAssertion(rdfs:label obo:CL_0000780 "multinuclear odontoclast") EquivalentClasses(obo:CL_0000780 ObjectIntersectionOf(obo:CL_0000588 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000780 obo:CL_0000588) SubClassOf(obo:CL_0000780 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000781)) # Class: obo:CL_0000781 (mononuclear odontoclast) @@ -10190,8 +10062,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000781 "Morphology: Mononuclear, highly vesicular; location: roots of deciduous (milk) teeth.") AnnotationAssertion(rdfs:label obo:CL_0000781 "mononuclear odontoclast") EquivalentClasses(obo:CL_0000781 ObjectIntersectionOf(obo:CL_0000588 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000781 obo:CL_0000588) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000781 obo:CL_0000778) # Class: obo:CL_0000782 (myeloid dendritic cell) @@ -10204,14 +10074,12 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000782 "mDC") AnnotationAssertion(rdfs:comment obo:CL_0000782 "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).") AnnotationAssertion(rdfs:label obo:CL_0000782 "myeloid dendritic cell") EquivalentClasses(obo:CL_0000782 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000763))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000782 obo:CL_0000990) # Class: obo:CL_0000783 (multinucleated phagocyte) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0000783 "A phagocyte formed by the fusion of mononuclear phagocytes.") AnnotationAssertion(rdfs:label obo:CL_0000783 "multinucleated phagocyte") EquivalentClasses(obo:CL_0000783 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000783 obo:CL_0000518) # Class: obo:CL_0000784 (plasmacytoid dendritic cell) @@ -10228,7 +10096,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "plasmacytoid monocy AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000784 "type 2 DC") AnnotationAssertion(rdfs:label obo:CL_0000784 "plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000784 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032606))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000784 obo:CL_0000451) SubClassOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037)) # Class: obo:CL_0000785 (mature B cell) @@ -10240,7 +10107,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000785 "mature B-lymphocyte AnnotationAssertion(rdfs:comment obo:CL_0000785 "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label obo:CL_0000785 "mature B cell") EquivalentClasses(obo:CL_0000785 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042113) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002335))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000785 obo:CL_0001201) SubClassOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818)) DisjointClasses(obo:CL_0000785 obo:CL_0000816) DisjointClasses(obo:CL_0000785 obo:CL_0000817) @@ -10261,7 +10127,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000786 "effector B-cell") AnnotationAssertion(rdfs:comment obo:CL_0000786 "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive.") AnnotationAssertion(rdfs:label obo:CL_0000786 "plasma cell") EquivalentClasses(obo:CL_0000786 ObjectIntersectionOf(obo:CL_0000946 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017508) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0005794) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019814) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001935))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000786 obo:CL_0000946) SubClassOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980)) # Class: obo:CL_0000787 (memory B cell) @@ -10273,7 +10138,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000787 "memory B-lymphocyte AnnotationAssertion(rdfs:comment obo:CL_0000787 "Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.") AnnotationAssertion(rdfs:label obo:CL_0000787 "memory B cell") EquivalentClasses(obo:CL_0000787 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002344))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000787 obo:CL_0000785) # Class: obo:CL_0000788 (naive B cell) @@ -10284,7 +10148,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000788 "naive B-lymphocyte" AnnotationAssertion(rdfs:comment obo:CL_0000788 "This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive.") AnnotationAssertion(rdfs:label obo:CL_0000788 "naive B cell") EquivalentClasses(obo:CL_0000788 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0002344) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000788 obo:CL_0000785) SubClassOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818)) # Class: obo:CL_0000789 (alpha-beta T cell) @@ -10295,7 +10158,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000789 "alpha-beta T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000789 "alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000789 "alpha-beta T cell") EquivalentClasses(obo:CL_0000789 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042105))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000789 obo:CL_0000084) DisjointClasses(obo:CL_0000789 obo:CL_0000798) # Class: obo:CL_0000790 (immature alpha-beta T cell) @@ -10306,7 +10168,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000790 "immature alpha-beta AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000790 "immature alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000790 "immature alpha-beta T cell") EquivalentClasses(obo:CL_0000790 ObjectIntersectionOf(obo:CL_0000789 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000790 obo:CL_0000789) # Class: obo:CL_0000791 (mature alpha-beta T cell) @@ -10316,7 +10177,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000791 "mature alpha-beta T AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000791 "mature alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000791 "mature alpha-beta T cell") EquivalentClasses(obo:CL_0000791 ObjectIntersectionOf(obo:CL_0000789 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000791 obo:CL_0000789) SubClassOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000790)) # Class: obo:CL_0000792 (CD4-positive, CD25-positive, alpha-beta regulatory T cell) @@ -10333,7 +10193,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000792 "CD4-positive, CD25- AnnotationAssertion(rdfs:comment obo:CL_0000792 "This cell type is compatible with the HIPC Lyoplate markers for 'Treg'. The inclusion of CD127lo in the logical definition is compatible with both human and mouse T cells of this subtype.") AnnotationAssertion(rdfs:label obo:CL_0000792 "CD4-positive, CD25-positive, alpha-beta regulatory T cell") EquivalentClasses(obo:CL_0000792 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001869))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000792 obo:CL_0000624) # Class: obo:CL_0000793 (CD4-positive, alpha-beta intraepithelial T cell) @@ -10345,7 +10204,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000793 "CD4-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000793 "CD4-positive, alpha-beta intraepithelial T cell") EquivalentClasses(obo:CL_0000793 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000793 obo:CL_0000624) SubClassOf(obo:CL_0000793 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000810)) # Class: obo:CL_0000794 (CD8-positive, alpha-beta cytotoxic T cell) @@ -10366,7 +10224,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000794 "CD8-positive, alpha AnnotationAssertion(rdfs:comment obo:CL_0000794 "Note that while T cells of this subset are loosely referred to 'cytotoxic T cells,' as many other T cell types, including CD4-positive, alpha-beta T cells and gamma-delta T cells exhibit cytotoxicity in vitro and in vivo.") AnnotationAssertion(rdfs:label obo:CL_0000794 "CD8-positive, alpha-beta cytotoxic T cell") EquivalentClasses(obo:CL_0000794 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003466) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003499) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0033380) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000794 obo:CL_0000625) SubClassOf(obo:CL_0000794 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906)) # Class: obo:CL_0000795 (CD8-positive, alpha-beta regulatory T cell) @@ -10387,7 +10244,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000795 "CD8-positive, alpha-beta regulatory T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000795 "CD8-positive, alpha-beta regulatory T cell") EquivalentClasses(obo:CL_0000795 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000795 obo:CL_0000625) # Class: obo:CL_0000796 (CD8-alpha-beta-positive, alpha-beta intraepithelial T cell) @@ -10399,7 +10255,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000796 "CD8-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000796 "CD8-positive, alpha-beta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000796 "CD8-alpha-beta-positive, alpha-beta intraepithelial T cell") EquivalentClasses(obo:CL_0000796 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000796 obo:CL_0000797) # Class: obo:CL_0000797 (alpha-beta intraepithelial T cell) @@ -10411,7 +10266,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000797 "alpha-beta intraepi AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000797 "alpha-beta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000797 "alpha-beta intraepithelial T cell") EquivalentClasses(obo:CL_0000797 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000797 obo:CL_0000791) # Class: obo:CL_0000798 (gamma-delta T cell) @@ -10424,7 +10278,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000798 "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways.") AnnotationAssertion(rdfs:label obo:CL_0000798 "gamma-delta T cell") EquivalentClasses(obo:CL_0000798 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0042106))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000798 obo:CL_0000084) # Class: obo:CL_0000799 (immature gamma-delta T cell) @@ -10435,7 +10288,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000799 "immature gamma-delt AnnotationAssertion(rdfs:comment obo:CL_0000799 "Note that gamma-delta T cells have both thymic and extrathymic differentiation pathways.") AnnotationAssertion(rdfs:label obo:CL_0000799 "immature gamma-delta T cell") EquivalentClasses(obo:CL_0000799 ObjectIntersectionOf(obo:CL_0000798 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0042492) ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000799 obo:CL_0000798) SubClassOf(obo:CL_0000799 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000807)) # Class: obo:CL_0000800 (mature gamma-delta T cell) @@ -10446,7 +10298,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000800 "mature gamma-delta AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000800 "mature gamma-delta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000800 "mature gamma-delta T cell") EquivalentClasses(obo:CL_0000800 ObjectIntersectionOf(obo:CL_0000798 ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000800 obo:CL_0000798) SubClassOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000799)) # Class: obo:CL_0000801 (gamma-delta intraepithelial T cell) @@ -10459,7 +10310,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000801 "gamma-delta intraep AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000801 "gamma-delta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000801 "gamma-delta intraepithelial T cell") EquivalentClasses(obo:CL_0000801 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001277) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002385))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000801 obo:CL_0000800) # Class: obo:CL_0000802 (CD8-alpha alpha positive, gamma-delta intraepithelial T cell) @@ -10471,7 +10321,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000802 "CD8-positive, gamma AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000802 "CD8-positive, gamma-delta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000802 "CD8-alpha alpha positive, gamma-delta intraepithelial T cell") EquivalentClasses(obo:CL_0000802 ObjectIntersectionOf(obo:CL_0000801 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000802 obo:CL_0000801) # Class: obo:CL_0000803 (CD4-negative CD8-negative gamma-delta intraepithelial T cell) @@ -10483,7 +10332,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000803 "CD4-positive, gamma AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000803 "CD4-positive, gamma-delta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000803 "CD4-negative CD8-negative gamma-delta intraepithelial T cell") EquivalentClasses(obo:CL_0000803 ObjectIntersectionOf(obo:CL_0000801 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000803 obo:CL_0000801) # Class: obo:CL_0000804 (obo:CL_0000804) @@ -10502,7 +10350,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000805 "immature single pos AnnotationAssertion(rdfs:comment obo:CL_0000805 "Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages.") AnnotationAssertion(rdfs:label obo:CL_0000805 "immature single positive thymocyte") EquivalentClasses(obo:CL_0000805 ObjectIntersectionOf(obo:CL_0000893 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0043384) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000805 obo:CL_0000893) SubClassOf(obo:CL_0000805 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000808)) # Class: obo:CL_0000806 (DN2 thymocyte) @@ -10566,7 +10413,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000809 "double-positive, al AnnotationAssertion(rdfs:comment obo:CL_0000809 "Thymocytes of this stage are undergoing positive and negative selection.") AnnotationAssertion(rdfs:label obo:CL_0000809 "double-positive, alpha-beta thymocyte") EquivalentClasses(obo:CL_0000809 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000809 obo:CL_0000790) SubClassOf(obo:CL_0000809 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000805)) # Class: obo:CL_0000810 (CD4-positive, alpha-beta thymocyte) @@ -10578,7 +10424,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "CD4-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000810 "SP CD4 cell") AnnotationAssertion(rdfs:label obo:CL_0000810 "CD4-positive, alpha-beta thymocyte") EquivalentClasses(obo:CL_0000810 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000810 obo:CL_0000790) SubClassOf(obo:CL_0000810 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809)) # Class: obo:CL_0000811 (CD8-positive, alpha-beta thymocyte) @@ -10591,7 +10436,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000811 "SP CD8 cell") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000811 "CD8-positive, alpha-beta immature T cell") AnnotationAssertion(rdfs:label obo:CL_0000811 "CD8-positive, alpha-beta thymocyte") EquivalentClasses(obo:CL_0000811 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000025402))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000811 obo:CL_0000790) SubClassOf(obo:CL_0000811 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809)) # Class: obo:CL_0000812 (obo:CL_0000812) @@ -10609,7 +10453,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000813 "memory T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000813 "memory T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000813 "memory T cell") EquivalentClasses(obo:CL_0000813 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001603) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002286) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000813 obo:CL_0002419) DisjointClasses(obo:CL_0000813 obo:CL_0000898) # Class: obo:CL_0000814 (mature NK T cell) @@ -10625,7 +10468,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural kill AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000814 "mature natural killer T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000814 "mature NK T cell") EquivalentClasses(obo:CL_0000814 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001874) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032394) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000814 obo:CL_0000791) SubClassOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002042)) # Class: obo:CL_0000815 (regulatory T cell) @@ -10645,7 +10487,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000815 "regulatory T-lympho AnnotationAssertion(rdfs:comment obo:CL_0000815 "This cell type may express FoxP3 and CD25 and secretes IL-10 and TGF-beta.") AnnotationAssertion(rdfs:label obo:CL_0000815 "regulatory T cell") EquivalentClasses(obo:CL_0000815 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000815 obo:CL_0002419) # Class: obo:CL_0000816 (immature B cell) @@ -10668,7 +10509,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000817 "CALOHA:TS-0819") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000817 "pre-B cell") AnnotationAssertion(rdfs:label obo:CL_0000817 "precursor B cell") EquivalentClasses(obo:CL_0000817 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000817 obo:CL_0001201) DisjointClasses(obo:CL_0000817 obo:CL_0000826) # Class: obo:CL_0000818 (transitional stage B cell) @@ -10684,7 +10524,6 @@ AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000818 "T3 B cell") AnnotationAssertion(rdfs:comment obo:CL_0000818 "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'.") AnnotationAssertion(rdfs:label obo:CL_0000818 "transitional stage B cell") EquivalentClasses(obo:CL_0000818 ObjectIntersectionOf(obo:CL_0001201 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0002335) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001932))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000818 obo:CL_0001201) SubClassOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000816)) # Class: obo:CL_0000819 (B-1 B cell) @@ -10702,7 +10541,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000819 "B1 cell") AnnotationAssertion(rdfs:comment obo:CL_0000819 "There are small numbers of B-1 cells found in the lymph nodes and spleen, while larger numbers can be found in the peritoneal and pleural cavities. B-1 B cells are reportedly CD11b-positive, CD20-positive, CD21-positive, CD27-positive, CD44-positive, CD45RB-positive, CD48-positive, CD70-negative, CD150-positive, CD244-negative, CD352-positive, sIgM-positive, and sIgD-low.") AnnotationAssertion(rdfs:label obo:CL_0000819 "B-1 B cell") EquivalentClasses(obo:CL_0000819 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045087) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0071753))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000819 obo:CL_0000785) # Class: obo:CL_0000820 (B-1a B cell) @@ -10720,7 +10558,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "CD5+ B1 cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000820 "CD5-positive B1 cell") AnnotationAssertion(rdfs:label obo:CL_0000820 "B-1a B cell") EquivalentClasses(obo:CL_0000820 ObjectIntersectionOf(obo:CL_0000819 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001839))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000820 obo:CL_0000819) # Class: obo:CL_0000821 (B-1b B cell) @@ -10735,7 +10572,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b B-lymphocyte") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000821 "B1b cell") AnnotationAssertion(rdfs:label obo:CL_0000821 "B-1b B cell") EquivalentClasses(obo:CL_0000821 ObjectIntersectionOf(obo:CL_0000819 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000821 obo:CL_0000819) # Class: obo:CL_0000822 (B-2 B cell) @@ -10752,7 +10588,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000822 "B-0 B cell") AnnotationAssertion(rdfs:comment obo:CL_0000822 "B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000822 "B-2 B cell") EquivalentClasses(obo:CL_0000822 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000822 obo:CL_0000785) # Class: obo:CL_0000823 (immature natural killer cell) @@ -10787,7 +10622,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11532393") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000825 "Most markers only described for human pro NK cells.") AnnotationAssertion(rdfs:label obo:CL_0000825 "pro-NK cell") EquivalentClasses(obo:CL_0000825 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001874) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001381) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000825 obo:CL_0000838) SubClassOf(obo:CL_0000825 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051)) # Class: obo:CL_0000826 (pro-B cell) @@ -10806,7 +10640,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11244048") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000826 "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative.") AnnotationAssertion(rdfs:label obo:CL_0000826 "pro-B cell") EquivalentClasses(obo:CL_0000826 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001903) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000006611) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0033152))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000826 obo:CL_0000838) SubClassOf(obo:CL_0000826 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051)) # Class: obo:CL_0000827 (pro-T cell) @@ -10819,7 +10652,6 @@ AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000827 "DN1 thymocyte") AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000827 "TN1 cell") AnnotationAssertion(rdfs:label obo:CL_0000827 "pro-T cell") EquivalentClasses(obo:CL_0000827 ObjectIntersectionOf(obo:CL_0000838 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000827 obo:CL_0000838) SubClassOf(obo:CL_0000827 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000051)) # Class: obo:CL_0000828 (thromboblast) @@ -10828,7 +10660,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000828 "Note that this is a non-mammalian cell type.") AnnotationAssertion(rdfs:label obo:CL_0000828 "thromboblast") EquivalentClasses(obo:CL_0000828 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002574))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000828 obo:CL_0000839) SubClassOf(obo:CL_0000828 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050)) # Class: obo:CL_0000829 (basophilic myeloblast) @@ -10836,7 +10667,6 @@ SubClassOf(obo:CL_0000828 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000050)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000829 "A myeloblast committed to the basophil lineage.") AnnotationAssertion(rdfs:label obo:CL_0000829 "basophilic myeloblast") EquivalentClasses(obo:CL_0000829 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000829 obo:CL_0000835) SubClassOf(obo:CL_0000829 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000613)) # Class: obo:CL_0000830 (basophilic promyelocyte) @@ -10845,7 +10675,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000830 "FMA:84208") AnnotationAssertion(rdfs:label obo:CL_0000830 "basophilic promyelocyte") EquivalentClasses(obo:CL_0000830 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000830 obo:CL_0000836) SubClassOf(obo:CL_0000830 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000829)) # Class: obo:CL_0000831 (mast cell progenitor) @@ -10858,7 +10687,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000831 "colony forming un AnnotationAssertion(rdfs:comment obo:CL_0000831 "MCP are CD16-positive, CD32-positive, CD34-positive, CD45-positive, integrin beta-7-positive, and lin-negative (CD2, CD3e, CD4, CD5, CD8a, CD14, CD19, CD20, CD27, integrin alpha-M, ly6c, ly6g, NCAM-1, and ter119). These cells also express the transcription factors GATA-1, GATA-2, and MITF, but not C/EBPa.") AnnotationAssertion(rdfs:label obo:CL_0000831 "mast cell progenitor") EquivalentClasses(obo:CL_0000831 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000005307) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002980) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016401) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060374) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000009143) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000007431))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000831 obo:CL_0000839) SubClassOf(obo:CL_0000831 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002028)) # Class: obo:CL_0000832 (eosinophilic myeloblast) @@ -10866,7 +10694,6 @@ SubClassOf(obo:CL_0000831 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002028)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") obo:IAO_0000115 obo:CL_0000832 "A myeloblast committed to the eosinophil lineage.") AnnotationAssertion(rdfs:label obo:CL_0000832 "eosinophilic myeloblast") EquivalentClasses(obo:CL_0000832 ObjectIntersectionOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000832 obo:CL_0000835) SubClassOf(obo:CL_0000832 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000611)) # Class: obo:CL_0000833 (eosinophilic promyelocyte) @@ -10875,7 +10702,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000833 "FMA:84199") AnnotationAssertion(rdfs:label obo:CL_0000833 "eosinophilic promyelocyte") EquivalentClasses(obo:CL_0000833 ObjectIntersectionOf(obo:CL_0000836 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030222))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000833 obo:CL_0000836) SubClassOf(obo:CL_0000833 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000832)) # Class: obo:CL_0000834 (neutrophil progenitor cell) @@ -10884,7 +10710,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000834 "neutrophil stem cell") AnnotationAssertion(rdfs:label obo:CL_0000834 "neutrophil progenitor cell") EquivalentClasses(obo:CL_0000834 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030223))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000834 obo:CL_0002191) SubClassOf(obo:CL_0000834 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557)) # Class: obo:CL_0000835 (myeloblast) @@ -10894,7 +10719,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000835 "BTO:0000187") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000835 "FMA:83524") AnnotationAssertion(rdfs:label obo:CL_0000835 "myeloblast") EquivalentClasses(obo:CL_0000835 ObjectIntersectionOf(obo:CL_0002191 ObjectSomeValuesFrom(obo:BFO_0000051 obo:CL_0017503) ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0000791) ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0042582) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0040072))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000835 obo:CL_0002191) SubClassOf(obo:CL_0000835 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557)) # Class: obo:CL_0000836 (promyelocyte) @@ -10917,7 +10741,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000837 "hemopoietic progeni AnnotationAssertion(rdfs:comment obo:CL_0000837 "Markers differ between mouse and human.") AnnotationAssertion(rdfs:label obo:CL_0000837 "hematopoietic multipotent progenitor cell") EquivalentClasses(obo:CL_0000837 ObjectIntersectionOf(obo:CL_0000988 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001402) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000837 obo:CL_0000988) SubClassOf(obo:CL_0000837 obo:CL_0008001) SubClassOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000037)) DisjointClasses(obo:CL_0000837 obo:CL_0002032) @@ -10932,7 +10755,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000838 "FMA:70338") AnnotationAssertion(rdfs:comment obo:CL_0000838 "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label obo:CL_0000838 "lymphoid lineage restricted progenitor cell") EquivalentClasses(obo:CL_0000838 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000838 obo:CL_0002031) DisjointClasses(obo:CL_0000838 obo:CL_0000839) # Class: obo:CL_0000839 (myeloid lineage restricted progenitor cell) @@ -10945,7 +10767,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000839 "FMA:70339") AnnotationAssertion(rdfs:comment obo:CL_0000839 "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label obo:CL_0000839 "myeloid lineage restricted progenitor cell") EquivalentClasses(obo:CL_0000839 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030099))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000839 obo:CL_0002031) # Class: obo:CL_0000840 (immature conventional dendritic cell) @@ -10953,7 +10774,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000840 "immature myeloid dendritic cell") AnnotationAssertion(rdfs:label obo:CL_0000840 "immature conventional dendritic cell") EquivalentClasses(obo:CL_0000840 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000840 obo:CL_0000990) SubClassOf(obo:CL_0000840 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029)) # Class: obo:CL_0000841 (mature conventional dendritic cell) @@ -10964,7 +10784,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000841 "FMA:83038") AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000841 "mature myeloid dendritic cell") AnnotationAssertion(rdfs:label obo:CL_0000841 "mature conventional dendritic cell") EquivalentClasses(obo:CL_0000841 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000841 obo:CL_0000990) SubClassOf(obo:CL_0000841 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000840)) # Class: obo:CL_0000842 (mononuclear cell) @@ -10977,7 +10796,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000842 "mononuclear leukocy AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000842 "peripheral blood mononuclear cell") AnnotationAssertion(rdfs:label obo:CL_0000842 "mononuclear cell") EquivalentClasses(obo:CL_0000842 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000842 obo:CL_0000738) # Class: obo:CL_0000843 (follicular B cell) @@ -10990,7 +10808,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000843 "follicular B-lympho AnnotationAssertion(rdfs:comment obo:CL_0000843 "Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000843 "follicular B cell") EquivalentClasses(obo:CL_0000843 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001879) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000843 obo:CL_0000785) # Class: obo:CL_0000844 (germinal center B cell) @@ -11005,7 +10822,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000844 "germinal center B-l AnnotationAssertion(rdfs:comment obo:CL_0000844 "Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.") AnnotationAssertion(rdfs:label obo:CL_0000844 "germinal center B cell") EquivalentClasses(obo:CL_0000844 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001745) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000844 obo:CL_0000785) SubClassOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000843)) # Class: obo:CL_0000845 (marginal zone B cell of spleen) @@ -11024,7 +10840,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000845 "marginal zone of sp AnnotationAssertion(rdfs:comment obo:CL_0000845 "MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000845 "marginal zone B cell of spleen") EquivalentClasses(obo:CL_0000845 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0071753))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000845 obo:CL_0000785) # Class: obo:CL_0000846 (vestibular dark cell) @@ -11146,7 +10961,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000860 "inflammatory monocy AnnotationAssertion(rdfs:comment obo:CL_0000860 "Markers: CCR2+CXCCR1 (human, mouse, rat).") AnnotationAssertion(rdfs:label obo:CL_0000860 "classical monocyte") EquivalentClasses(obo:CL_0000860 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002548) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006954) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001199))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000860 obo:CL_0000576) # Class: obo:CL_0000861 (elicited macrophage) @@ -11158,7 +10972,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000861 "wandering histiocyt AnnotationAssertion(rdfs:comment obo:CL_0000861 "Markers: CD11b+, CD68+; Mouse: F4/80+; role or process: immune, inflammation (inflammatory response).") AnnotationAssertion(rdfs:label obo:CL_0000861 "elicited macrophage") EquivalentClasses(obo:CL_0000861 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0006954) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000861 obo:CL_0000235) SubClassOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000860)) # Class: obo:CL_0000862 (suppressor macrophage) @@ -11167,7 +10980,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000862 "Markers: May express: IL10, TGFbeta.") AnnotationAssertion(rdfs:label obo:CL_0000862 "suppressor macrophage") EquivalentClasses(obo:CL_0000862 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000862 obo:CL_0000861) # Class: obo:CL_0000863 (inflammatory macrophage) @@ -11177,7 +10989,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28923980") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000863 "Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response).") AnnotationAssertion(rdfs:label obo:CL_0000863 "inflammatory macrophage") EquivalentClasses(obo:CL_0000863 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032611) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042554) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042742) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0051767))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000863 obo:CL_0000861) # Class: obo:CL_0000864 (tissue-resident macrophage) @@ -11188,7 +10999,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "fixed macrophage") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000864 "resting histiocyte") AnnotationAssertion(rdfs:label obo:CL_0000864 "tissue-resident macrophage") EquivalentClasses(obo:CL_0000864 ObjectIntersectionOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000479))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000864 obo:CL_0000235) # Class: obo:CL_0000865 (gastrointestinal tract (lamina propria) macrophage) @@ -11205,7 +11015,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000866 "Role or process: immune, clearance of apoptotic thymocytes, antigen-presentation.") AnnotationAssertion(rdfs:label obo:CL_0000866 "thymic macrophage") EquivalentClasses(obo:CL_0000866 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000866 obo:CL_0000864) # Class: obo:CL_0000867 (secondary lymphoid organ macrophage) @@ -11220,21 +11029,18 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000868 "MF.LN") AnnotationAssertion(rdfs:comment obo:CL_0000868 "Marker was observed on rat cells.") AnnotationAssertion(rdfs:label obo:CL_0000868 "lymph node macrophage") EquivalentClasses(obo:CL_0000868 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000029) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001813))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000868 obo:CL_0000867) # Class: obo:CL_0000869 (tonsillar macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16048540") obo:IAO_0000115 obo:CL_0000869 "A gut-associated lymphoid tissue macrophage found in tonsils.") AnnotationAssertion(rdfs:label obo:CL_0000869 "tonsillar macrophage") EquivalentClasses(obo:CL_0000869 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002372) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002395))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000869 obo:CL_0000884) # Class: obo:CL_0000870 (Peyer's patch macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000870 "A gut-associated lymphoid tissue macrophage found in the Peyer's patches.") AnnotationAssertion(rdfs:label obo:CL_0000870 "Peyer's patch macrophage") EquivalentClasses(obo:CL_0000870 ObjectIntersectionOf(obo:CL_0000885 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001211))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000870 obo:CL_0000885) # Class: obo:CL_0000871 (splenic macrophage) @@ -11243,7 +11049,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000871 "FMA:83026") AnnotationAssertion(rdfs:comment obo:CL_0000871 "Role or process: immune, clearance of apoptotic and senescent cells.") AnnotationAssertion(rdfs:label obo:CL_0000871 "splenic macrophage") EquivalentClasses(obo:CL_0000871 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002106) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000871 obo:CL_0000867) # Class: obo:CL_0000872 (splenic marginal zone macrophage) @@ -11251,7 +11056,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000872 "Markers: Mouse: F4/80-, MARCO+, SR-A+, SIGN-R1+, Dectin2+.") AnnotationAssertion(rdfs:label obo:CL_0000872 "splenic marginal zone macrophage") EquivalentClasses(obo:CL_0000872 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001806) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001884) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001885) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000006172))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000872 obo:CL_0000871) # Class: obo:CL_0000873 (splenic metallophillic macrophage) @@ -11259,7 +11063,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000873 "Markers: Mouse: F4/80-, Dectin2-low, sialoadhesin+.") AnnotationAssertion(rdfs:label obo:CL_0000873 "splenic metallophillic macrophage") EquivalentClasses(obo:CL_0000873 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001251) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0001959) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001806))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000873 obo:CL_0000871) # Class: obo:CL_0000874 (splenic red pulp macrophage) @@ -11267,7 +11070,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000874 "Markers: Mouse: F4/80+, CD68+, MR+, Dectin2+, macrosialin+, sialoadhesin-low; role or process: immune, clearance of senescent erythrocytes.") AnnotationAssertion(rdfs:label obo:CL_0000874 "splenic red pulp macrophage") EquivalentClasses(obo:CL_0000874 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001250) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001806) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006955) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0034102) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001931))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000874 obo:CL_0000871) # Class: obo:CL_0000875 (non-classical monocyte) @@ -11277,7 +11079,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000875 "resident monocyte") AnnotationAssertion(rdfs:comment obo:CL_0000875 "Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-.") AnnotationAssertion(rdfs:label obo:CL_0000875 "non-classical monocyte") EquivalentClasses(obo:CL_0000875 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0000587) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031294) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030224) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001206))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000875 obo:CL_0000576) SubClassOf(obo:CL_0000875 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002393)) # Class: obo:CL_0000876 (splenic white pulp macrophage) @@ -11286,14 +11087,12 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000876 "Markers: Mouse: F4/80-, CD68+, macrosialin+.") AnnotationAssertion(rdfs:label obo:CL_0000876 "splenic white pulp macrophage") EquivalentClasses(obo:CL_0000876 ObjectIntersectionOf(obo:CL_0000871 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001959) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001813) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002064))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000876 obo:CL_0000871) # Class: obo:CL_0000877 (splenic tingible body macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19631584") obo:IAO_0000115 obo:CL_0000877 "A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive.") AnnotationAssertion(rdfs:label obo:CL_0000877 "splenic tingible body macrophage") EquivalentClasses(obo:CL_0000877 ObjectIntersectionOf(obo:CL_0000876 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001249) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000010329) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000877 obo:CL_0000876) # Class: obo:CL_0000878 (central nervous system macrophage) @@ -11301,7 +11100,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(o AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000878 "CNS macrophage") AnnotationAssertion(rdfs:label obo:CL_0000878 "central nervous system macrophage") EquivalentClasses(obo:CL_0000878 ObjectIntersectionOf(obo:CL_0000864 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000878 obo:CL_0000864) # Class: obo:CL_0000879 (meningeal macrophage) @@ -11329,56 +11127,48 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(ob AnnotationAssertion(rdfs:label obo:CL_0000881 "perivascular macrophage") EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925))) SubClassOf(obo:CL_0000881 obo:CL_4033054) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_4042003) # Class: obo:CL_0000882 (thymic medullary macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9048205") obo:IAO_0000115 obo:CL_0000882 "A thymic macrophage found in the thymic medulla.") AnnotationAssertion(rdfs:label obo:CL_0000882 "thymic medullary macrophage") EquivalentClasses(obo:CL_0000882 ObjectIntersectionOf(obo:CL_0000866 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002124))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000882 obo:CL_0000866) # Class: obo:CL_0000883 (thymic cortical macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9048205") obo:IAO_0000115 obo:CL_0000883 "A thymic macrophage found in the thymic cortex.") AnnotationAssertion(rdfs:label obo:CL_0000883 "thymic cortical macrophage") EquivalentClasses(obo:CL_0000883 ObjectIntersectionOf(obo:CL_0000866 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002123))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000883 obo:CL_0000866) # Class: obo:CL_0000884 (mucosa-associated lymphoid tissue macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19906191") obo:IAO_0000115 obo:CL_0000884 "A tissue-resident macrophage found in the mucosa associated lymphoid tissue.") AnnotationAssertion(rdfs:label obo:CL_0000884 "mucosa-associated lymphoid tissue macrophage") EquivalentClasses(obo:CL_0000884 ObjectIntersectionOf(obo:CL_0000867 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001961))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000884 obo:CL_0000867) # Class: obo:CL_0000885 (gut-associated lymphoid tissue macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19906191") obo:IAO_0000115 obo:CL_0000885 "A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut.") AnnotationAssertion(rdfs:label obo:CL_0000885 "gut-associated lymphoid tissue macrophage") EquivalentClasses(obo:CL_0000885 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002387))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000885 obo:CL_0000884) # Class: obo:CL_0000886 (nasal and broncial associated lymphoid tissue macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16048540") obo:IAO_0000115 obo:CL_0000886 "A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues.") AnnotationAssertion(rdfs:label obo:CL_0000886 "nasal and broncial associated lymphoid tissue macrophage") EquivalentClasses(obo:CL_0000886 ObjectIntersectionOf(obo:CL_0000884 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002395))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000886 obo:CL_0000884) # Class: obo:CL_0000887 (lymph node subcapsular sinus macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:14668803") Annotation(oboInOwl:hasDbXref "PMID:17934446") Annotation(oboInOwl:hasDbXref "PMID:20228797") obo:IAO_0000115 obo:CL_0000887 "A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive.") AnnotationAssertion(rdfs:label obo:CL_0000887 "lymph node subcapsular sinus macrophage") EquivalentClasses(obo:CL_0000887 ObjectIntersectionOf(obo:CL_0000868 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001931) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032816) ObjectSomeValuesFrom(obo:RO_0002220 obo:UBERON_0002194))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000887 obo:CL_0000868) # Class: obo:CL_0000888 (lymph node tingible body macrophage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19631584") obo:IAO_0000115 obo:CL_0000888 "A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers.") AnnotationAssertion(rdfs:label obo:CL_0000888 "lymph node tingible body macrophage") EquivalentClasses(obo:CL_0000888 ObjectIntersectionOf(obo:CL_0000868 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002006) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002905) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043277))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000888 obo:CL_0000868) # Class: obo:CL_0000889 (myeloid suppressor cell) @@ -11386,7 +11176,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000889 "Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.") AnnotationAssertion(rdfs:label obo:CL_0000889 "myeloid suppressor cell") EquivalentClasses(obo:CL_0000889 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001501) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001006) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000889 obo:CL_0000766) # Class: obo:CL_0000890 (alternatively activated macrophage) @@ -11395,7 +11184,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28923980") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000890 "Role or process: tissue remodeling.") AnnotationAssertion(rdfs:label obo:CL_0000890 "alternatively activated macrophage") EquivalentClasses(obo:CL_0000890 ObjectIntersectionOf(obo:CL_0000861 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001844) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048771))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000890 obo:CL_0000861) # Class: obo:CL_0000891 (foam cell) @@ -11428,7 +11216,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000893 "XAO:0003159") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000893 "thymic lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000893 "thymocyte") EquivalentClasses(obo:CL_0000893 ObjectIntersectionOf(obo:CL_0000084 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000893 obo:CL_0002420) # Class: obo:CL_0000894 (DN1 thymic pro-T cell) @@ -11442,7 +11229,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "double negative 1") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000894 "preT.DN1.Th") AnnotationAssertion(rdfs:label obo:CL_0000894 "DN1 thymic pro-T cell") EquivalentClasses(obo:CL_0000894 ObjectIntersectionOf(obo:CL_0000827 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001307))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000894 obo:CL_0000827) SubClassOf(obo:CL_0000894 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002425)) # Class: obo:CL_0000895 (naive thymus-derived CD4-positive, alpha-beta T cell) @@ -11457,7 +11243,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000895 "naive thymus-derive AnnotationAssertion(rdfs:comment obo:CL_0000895 "These cells have not been exposed to antigen following thymic T-cell selection; found in blood and secondary lymphoid organs. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD4+ T cell', but includes additional markers known to be expressed on naive CD4+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000895 "naive thymus-derived CD4-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000895 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000895 obo:CL_0000624) SubClassOf(obo:CL_0000895 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002436)) # Class: obo:CL_0000896 (activated CD4-positive, alpha-beta T cell) @@ -11468,7 +11253,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000896 "activated CD4-posit AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000896 "activated CD4-positive, alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000896 "activated CD4-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000896 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000896 obo:CL_0000624) SubClassOf(obo:CL_0000896 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000895)) # Class: obo:CL_0000897 (CD4-positive, alpha-beta memory T cell) @@ -11491,7 +11275,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000898 "naive T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000898 "naive T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000898 "naive T cell") EquivalentClasses(obo:CL_0000898 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000898 obo:CL_0002419) # Class: obo:CL_0000899 (T-helper 17 cell) @@ -11510,7 +11293,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000899 "helper T cell type AnnotationAssertion(rdfs:comment obo:CL_0000899 "This cell type is compatible with the HIPC Lyoplate markers for 'Th17 CD4+ T cell', but its logical definition includes additional known characteristics of T-helper 17 T cells.") AnnotationAssertion(rdfs:label obo:CL_0000899 "T-helper 17 cell") EquivalentClasses(obo:CL_0000899 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003455) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032620))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000899 obo:CL_0000492) SubClassOf(obo:CL_0000899 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0000900 (naive thymus-derived CD8-positive, alpha-beta T cell) @@ -11524,7 +11306,6 @@ AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000900 "T.8Nve.Sp") AnnotationAssertion(rdfs:comment obo:CL_0000900 "This cell traffics in secondary lymphoid organs and blood. This cell type is compatible with the HIPC Lyoplate markers for 'naive CD8+ T cell', but includes additional markers known to be expressed on naive CD8+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000900 "naive thymus-derived CD8-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000900 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001307))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000900 obo:CL_0000625) SubClassOf(obo:CL_0000900 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002437)) # Class: obo:CL_0000901 (Tr1 cell) @@ -11538,7 +11319,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000901 "Tr1 T-lymphocyte") AnnotationAssertion(rdfs:comment obo:CL_0000901 "These cells are reportedly induced by IL-10 and are capable of producing IFN-gamma, IL-5, IL-10, and TGF-beta.)") AnnotationAssertion(rdfs:label obo:CL_0000901 "Tr1 cell") EquivalentClasses(obo:CL_0000901 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000901 obo:CL_0000624) SubClassOf(obo:CL_0000901 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0000902 (induced T-regulatory cell) @@ -11554,7 +11334,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000902 "aTreg") AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000902 "adaptive Treg") AnnotationAssertion(rdfs:label obo:CL_0000902 "induced T-regulatory cell") EquivalentClasses(obo:CL_0000902 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001852) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000902 obo:CL_0000792) # Class: obo:CL_0000903 (natural T-regulatory cell) @@ -11567,7 +11346,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000903 "natural regulatory T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000903 "natural T-regulatory cell") EquivalentClasses(obo:CL_0000903 ObjectIntersectionOf(obo:CL_0000792 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001852) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000903 obo:CL_0000792) # Class: obo:CL_0000904 (central memory CD4-positive, alpha-beta T cell) @@ -11583,7 +11361,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000904 "central memory CD4- AnnotationAssertion(rdfs:comment obo:CL_0000904 "This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD4+ T cell', but includes additional markers known to be expressed on central memory CD4+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000904 "central memory CD4-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000904 ObjectIntersectionOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000904 obo:CL_0001204) # Class: obo:CL_0000905 (effector memory CD4-positive, alpha-beta T cell) @@ -11599,7 +11376,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000905 "effector memory CD4 AnnotationAssertion(rdfs:comment obo:CL_0000905 "This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD4+ T cell', but includes additional markers known to be expressed on effector memory CD4+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000905 "effector memory CD4-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000905 ObjectIntersectionOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000905 obo:CL_0001204) # Class: obo:CL_0000906 (activated CD8-positive, alpha-beta T cell) @@ -11609,7 +11385,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000906 "activated CD8-posit AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000906 "activated CD8-positive, alpha-beta T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000906 "activated CD8-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000906 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000906 obo:CL_0000625) SubClassOf(obo:CL_0000906 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000900)) # Class: obo:CL_0000907 (central memory CD8-positive, alpha-beta T cell) @@ -11626,7 +11401,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000907 "central memory CD8- AnnotationAssertion(rdfs:comment obo:CL_0000907 "This cell type is compatible with the HIPC Lyoplate markers for 'central memory CD8+ T cell', but includes additional markers known to be expressed on central memory CD8+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000907 "central memory CD8-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000907 ObjectIntersectionOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001203))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000907 obo:CL_0001203) # Class: obo:CL_0000908 (CD8-positive, alpha-beta cytokine secreting effector T cell) @@ -11636,7 +11410,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000908 "CD8-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000908 "CD8-positive, alpha-beta cytokine secreting effector T cell") EquivalentClasses(obo:CL_0000908 ObjectIntersectionOf(obo:CL_0000625 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000908 obo:CL_0000625) SubClassOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906)) # Class: obo:CL_0000909 (CD8-positive, alpha-beta memory T cell) @@ -11661,7 +11434,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000910 "cytotoxic T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000910 "cytotoxic T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000910 "cytotoxic T cell") EquivalentClasses(obo:CL_0000910 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000910 obo:CL_0000911) # Class: obo:CL_0000911 (effector T cell) @@ -11671,7 +11443,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000911 "effector T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000911 "effector T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000911 "effector T cell") EquivalentClasses(obo:CL_0000911 ObjectIntersectionOf(obo:CL_0002419 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0045026) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045058))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000911 obo:CL_0002419) # Class: obo:CL_0000912 (helper T cell) @@ -11684,7 +11455,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "helper T-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000912 "helper T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000912 "helper T cell") EquivalentClasses(obo:CL_0000912 ObjectIntersectionOf(obo:CL_0000911 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000912 obo:CL_0000911) # Class: obo:CL_0000913 (effector memory CD8-positive, alpha-beta T cell) @@ -11700,7 +11470,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000913 "effector memory CD8 AnnotationAssertion(rdfs:comment obo:CL_0000913 "This cell type is compatible with the HIPC Lyoplate markers for 'effector memory CD8+ T cell', but includes additional markers known to be expressed on effector memory CD8+ T cells.") AnnotationAssertion(rdfs:label obo:CL_0000913 "effector memory CD8-positive, alpha-beta T cell") EquivalentClasses(obo:CL_0000913 ObjectIntersectionOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001203) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000913 obo:CL_0001203) # Class: obo:CL_0000914 (immature NK T cell) @@ -11711,7 +11480,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NK T-lymph AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000914 "immature NKT cell") AnnotationAssertion(rdfs:label obo:CL_0000914 "immature NK T cell") EquivalentClasses(obo:CL_0000914 ObjectIntersectionOf(obo:CL_0000790 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003469))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000914 obo:CL_0000790) SubClassOf(obo:CL_0000914 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000809)) # Class: obo:CL_0000915 (CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell) @@ -11722,7 +11490,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000915 "CD8-alpha-alpha-pos AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000915 "CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell") EquivalentClasses(obo:CL_0000915 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000915 obo:CL_0000797) SubClassOf(obo:CL_0000915 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000811)) # Class: obo:CL_0000916 (dendritic epidermal T cell) @@ -11735,7 +11502,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000916 "dendritic epidermal AnnotationAssertion(rdfs:comment obo:CL_0000916 "In mice, DETC have an invariant T cell receptor.") AnnotationAssertion(rdfs:label obo:CL_0000916 "dendritic epidermal T cell") EquivalentClasses(obo:CL_0000916 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001003) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060054))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000916 obo:CL_0000800) SubClassOf(obo:CL_0000916 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002401)) # Class: obo:CL_0000917 (Tc1 cell) @@ -11756,7 +11522,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000917 "Th1 non-TFH CD8-pos AnnotationAssertion(rdfs:comment obo:CL_0000917 "This cell type is compatible with the HIPC Lyoplate markers for 'Tc1 CD8+ T cell', but its logical definition includes additional known characteristics of Tc1 T cells.") AnnotationAssertion(rdfs:label obo:CL_0000917 "Tc1 cell") EquivalentClasses(obo:CL_0000917 ObjectIntersectionOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001835) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003463) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000917 obo:CL_0000908) # Class: obo:CL_0000918 (Tc2 cell) @@ -11774,7 +11539,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000918 "Th2 non-TFH CD8-pos AnnotationAssertion(rdfs:comment obo:CL_0000918 "This cell type is compatible with the HIPC Lyoplate markers for 'non-Tc1/Tc17 CD8+ T cell' (see CL:0001052), but includes the additional necessary and sufficient conditions to allow classification as a Tc2 T cell.") AnnotationAssertion(rdfs:label obo:CL_0000918 "Tc2 cell") EquivalentClasses(obo:CL_0000918 ObjectIntersectionOf(obo:CL_0000908 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001941) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001202) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000918 obo:CL_0000908) # Class: obo:CL_0000919 (CD8-positive, CD25-positive, alpha-beta regulatory T cell) @@ -11791,7 +11555,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25- AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000919 "CD8-positive, CD25-positive, alpha-beta regulatory T cell") EquivalentClasses(obo:CL_0000919 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001380))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000919 obo:CL_0000795) SubClassOf(obo:CL_0000919 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906)) # Class: obo:CL_0000920 (CD8-positive, CD28-negative, alpha-beta regulatory T cell) @@ -11810,7 +11573,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28- AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000920 "CD8-positive, CD28-negative, alpha-beta regulatory T cell") EquivalentClasses(obo:CL_0000920 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001350) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001841))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000920 obo:CL_0000795) SubClassOf(obo:CL_0000920 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906)) # Class: obo:CL_0000921 (type I NK T cell) @@ -11825,7 +11587,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000921 "invariant NK T ce AnnotationAssertion(rdfs:comment obo:CL_0000921 "In mouse the canonical TCR is V-alpha-14, and in humans it is V-alpha 24.") AnnotationAssertion(rdfs:label obo:CL_0000921 "type I NK T cell") EquivalentClasses(obo:CL_0000921 ObjectIntersectionOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043208))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000921 obo:CL_0000814) # Class: obo:CL_0000922 (type II NK T cell) @@ -11836,7 +11597,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NK T-lympho AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000922 "type II NKT cell") AnnotationAssertion(rdfs:label obo:CL_0000922 "type II NK T cell") EquivalentClasses(obo:CL_0000922 ObjectIntersectionOf(obo:CL_0000814 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002288))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000922 obo:CL_0000814) # Class: obo:CL_0000923 (CD4-positive type I NK T cell) @@ -11848,7 +11608,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000923 "CD4-positive type I AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000923 "NKT.4+.SP") AnnotationAssertion(rdfs:label obo:CL_0000923 "CD4-positive type I NK T cell") EquivalentClasses(obo:CL_0000923 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000923 obo:CL_0000921) # Class: obo:CL_0000924 (CD4-negative, CD8-negative type I NK T cell) @@ -11860,7 +11619,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000924 "CD4-negative, CD8-n AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_0000924 "NKT.4-.Sp") AnnotationAssertion(rdfs:label obo:CL_0000924 "CD4-negative, CD8-negative type I NK T cell") EquivalentClasses(obo:CL_0000924 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000924 obo:CL_0000921) # Class: obo:CL_0000925 (activated CD4-positive type I NK T cell) @@ -11871,7 +11629,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-posit AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000925 "activated CD4-positive type I NKT cell") AnnotationAssertion(rdfs:label obo:CL_0000925 "activated CD4-positive type I NK T cell") EquivalentClasses(obo:CL_0000925 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000925 obo:CL_0000921) SubClassOf(obo:CL_0000925 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000923)) # Class: obo:CL_0000926 (CD4-positive type I NK T cell secreting interferon-gamma) @@ -11884,7 +11641,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000926 "CD4-positive type I NKT cell secreting interferon-gamma") AnnotationAssertion(rdfs:label obo:CL_0000926 "CD4-positive type I NK T cell secreting interferon-gamma") EquivalentClasses(obo:CL_0000926 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002827) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000926 obo:CL_0000921) SubClassOf(obo:CL_0000926 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000925)) # Class: obo:CL_0000927 (CD4-positive type I NK T cell secreting interleukin-4) @@ -11897,7 +11653,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000927 "CD4-positive type I NKT cell secreting interleukin-4") AnnotationAssertion(rdfs:label obo:CL_0000927 "CD4-positive type I NK T cell secreting interleukin-4") EquivalentClasses(obo:CL_0000927 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001004) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032616) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000927 obo:CL_0000921) SubClassOf(obo:CL_0000927 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000925)) # Class: obo:CL_0000928 (activated CD4-negative, CD8-negative type I NK T cell) @@ -11909,7 +11664,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negat AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000928 "activated CD4-negative, CD8-negative type I NKT cell") AnnotationAssertion(rdfs:label obo:CL_0000928 "activated CD4-negative, CD8-negative type I NK T cell") EquivalentClasses(obo:CL_0000928 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002369))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000928 obo:CL_0000921) SubClassOf(obo:CL_0000928 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000924)) # Class: obo:CL_0000929 (CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma) @@ -11922,7 +11676,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-n AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000929 "CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma") AnnotationAssertion(rdfs:label obo:CL_0000929 "CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma") EquivalentClasses(obo:CL_0000929 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002827) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000929 obo:CL_0000921) SubClassOf(obo:CL_0000929 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000928)) # Class: obo:CL_0000930 (CD4-negative, CD8-negative type I NK T cell secreting interleukin-4) @@ -11935,7 +11688,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-n AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000930 "CD4-negative, CD8-negative type I NKT cell secreting interleukin-4") AnnotationAssertion(rdfs:label obo:CL_0000930 "CD4-negative, CD8-negative type I NK T cell secreting interleukin-4") EquivalentClasses(obo:CL_0000930 ObjectIntersectionOf(obo:CL_0000921 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002830) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000930 obo:CL_0000921) SubClassOf(obo:CL_0000930 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000928)) # Class: obo:CL_0000931 (activated type II NK T cell) @@ -11947,7 +11699,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II N AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000931 "activated type II NKT cell") AnnotationAssertion(rdfs:label obo:CL_0000931 "activated type II NK T cell") EquivalentClasses(obo:CL_0000931 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002369))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000931 obo:CL_0000922) # Class: obo:CL_0000932 (type II NK T cell secreting interferon-gamma) @@ -11959,7 +11710,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NK T-lympho AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000932 "type II NKT cell secreting interferon-gamma") AnnotationAssertion(rdfs:label obo:CL_0000932 "type II NK T cell secreting interferon-gamma") EquivalentClasses(obo:CL_0000932 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000932 obo:CL_0000922) SubClassOf(obo:CL_0000932 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000931)) # Class: obo:CL_0000933 (type II NK T cell secreting interleukin-4) @@ -11972,7 +11722,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NK T-lympho AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000933 "type II NKT cell secreting interleukin-4") AnnotationAssertion(rdfs:label obo:CL_0000933 "type II NK T cell secreting interleukin-4") EquivalentClasses(obo:CL_0000933 ObjectIntersectionOf(obo:CL_0000922 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001343) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000933 obo:CL_0000922) SubClassOf(obo:CL_0000933 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000931)) # Class: obo:CL_0000934 (CD4-positive, alpha-beta cytotoxic T cell) @@ -11983,7 +11732,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000934 "CD4-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000934 "CD4-positive, alpha-beta cytotoxic T cell") EquivalentClasses(obo:CL_0000934 ObjectIntersectionOf(obo:CL_0000624 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001913) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000934 obo:CL_0000624) SubClassOf(obo:CL_0000934 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0000935 (CD4-negative, CD8-negative, alpha-beta intraepithelial T cell) @@ -11994,7 +11742,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000935 "CD4-negative, CD8-n AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000935 "CD4-negative, CD8-negative, alpha-beta intraepithelial T cell") EquivalentClasses(obo:CL_0000935 ObjectIntersectionOf(obo:CL_0000797 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000025403))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000935 obo:CL_0000797) # Class: obo:CL_0000936 (early lymphoid progenitor) @@ -12006,7 +11753,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000936 "Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.") AnnotationAssertion(rdfs:label obo:CL_0000936 "early lymphoid progenitor") EquivalentClasses(obo:CL_0000936 ObjectIntersectionOf(obo:CL_0000837 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030098))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000936 obo:CL_0000837) SubClassOf(obo:CL_0000936 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002035)) # Class: obo:CL_0000937 (pre-natural killer cell) @@ -12051,7 +11797,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000940 "mucosal invariant T-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000940 "mucosal invariant T cell") EquivalentClasses(obo:CL_0000940 ObjectIntersectionOf(obo:CL_0000791 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002227) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032394) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000940 obo:CL_0000791) # Class: obo:CL_0000941 (thymic conventional dendritic cell) @@ -12059,7 +11804,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000941 "In the mouse this cell expresses CD8-alpha-alpha.") AnnotationAssertion(rdfs:label obo:CL_0000941 "thymic conventional dendritic cell") EquivalentClasses(obo:CL_0000941 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002370) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000941 obo:CL_0000990) SubClassOf(obo:CL_0000941 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894)) # Class: obo:CL_0000942 (thymic plasmacytoid dendritic cell) @@ -12067,7 +11811,6 @@ SubClassOf(obo:CL_0000941 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:pam") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:19941119") obo:IAO_0000115 obo:CL_0000942 "A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive.") AnnotationAssertion(rdfs:label obo:CL_0000942 "thymic plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000942 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000942 obo:CL_0000784) SubClassOf(obo:CL_0000942 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000894)) # Class: obo:CL_0000943 (Be1 Cell) @@ -12078,7 +11821,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000943 "B effector cell t AnnotationAssertion(rdfs:comment obo:CL_0000943 "Be1 cells are also reportedly capable of secreting IL-6, IL-10, and IL-12. They are also reportedly CD11b-negative and B220-positive.") AnnotationAssertion(rdfs:label obo:CL_0000943 "Be1 Cell") EquivalentClasses(obo:CL_0000943 ObjectIntersectionOf(obo:CL_0000968 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032623) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032640) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045627))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000943 obo:CL_0000968) # Class: obo:CL_0000944 (Be2 cell) @@ -12088,14 +11830,12 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000944 "B effector cell t AnnotationAssertion(rdfs:comment obo:CL_0000944 "Be2 cells are also reportedly capable of secreting IL-13 and TNF. They are also reportedly CD11b-negative and B220-positive.") AnnotationAssertion(rdfs:label obo:CL_0000944 "Be2 cell") EquivalentClasses(obo:CL_0000944 ObjectIntersectionOf(obo:CL_0000968 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032623) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032633) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032635) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045630))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000944 obo:CL_0000968) # Class: obo:CL_0000945 (lymphocyte of B lineage) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000945 "A lymphocyte of B lineage with the commitment to express an immunoglobulin complex.") AnnotationAssertion(rdfs:comment obo:CL_0000945 "Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells). Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex).") AnnotationAssertion(rdfs:label obo:CL_0000945 "lymphocyte of B lineage") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000945 obo:CL_0000542) SubClassOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826)) # Class: obo:CL_0000946 (antibody secreting cell) @@ -12103,14 +11843,12 @@ SubClassOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:0721601464") Annotation(oboInOwl:hasDbXref "ISBN:0781735149") obo:IAO_0000115 obo:CL_0000946 "A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin.") AnnotationAssertion(rdfs:label obo:CL_0000946 "antibody secreting cell") EquivalentClasses(obo:CL_0000946 ObjectIntersectionOf(obo:CL_0000945 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0042571))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000946 obo:CL_0000945) # Class: obo:CL_0000947 (IgE plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000947 "A long lived plasma cell that secretes IgE.") AnnotationAssertion(rdfs:label obo:CL_0000947 "IgE plasma cell") EquivalentClasses(obo:CL_0000947 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000947 obo:CL_0000974) # Class: obo:CL_0000948 (IgE memory B cell) @@ -12124,42 +11862,36 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000948 "memory IgE B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000948 "IgE memory B cell") EquivalentClasses(obo:CL_0000948 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071742))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000948 obo:CL_0000972) # Class: obo:CL_0000949 (IgD plasmablast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000949 "A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult.") AnnotationAssertion(rdfs:label obo:CL_0000949 "IgD plasmablast") EquivalentClasses(obo:CL_0000949 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071739))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000949 obo:CL_0000980) # Class: obo:CL_0000950 (IgE plasmablast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000950 "A plasmablast that secretes IgE.") AnnotationAssertion(rdfs:label obo:CL_0000950 "IgE plasmablast") EquivalentClasses(obo:CL_0000950 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000950 obo:CL_0000980) # Class: obo:CL_0000951 (IgE short lived plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000951 "A short lived plasma cell that secretes IgE.") AnnotationAssertion(rdfs:label obo:CL_0000951 "IgE short lived plasma cell") EquivalentClasses(obo:CL_0000951 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071743))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000951 obo:CL_0000975) # Class: obo:CL_0000952 (preBCR-positive large pre-B-II cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000952 "An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.") AnnotationAssertion(rdfs:label obo:CL_0000952 "preBCR-positive large pre-B-II cell") EquivalentClasses(obo:CL_0000952 ObjectIntersectionOf(obo:CL_0000957 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071708) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001859))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000952 obo:CL_0000957) # Class: obo:CL_0000953 (preBCR-negative large pre-B-II cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9785673") obo:IAO_0000115 obo:CL_0000953 "A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.") AnnotationAssertion(rdfs:label obo:CL_0000953 "preBCR-negative large pre-B-II cell") EquivalentClasses(obo:CL_0000953 ObjectIntersectionOf(obo:CL_0000957 ObjectSomeValuesFrom(obo:CL_4030044 obo:GO_0071708) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0035369) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001859))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000953 obo:CL_0000957) # Class: obo:CL_0000954 (small pre-B-II cell) @@ -12168,7 +11900,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000954 "small pre-BII cell" AnnotationAssertion(rdfs:comment obo:CL_0000954 "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") AnnotationAssertion(rdfs:label obo:CL_0000954 "small pre-B-II cell") EquivalentClasses(obo:CL_0000954 ObjectIntersectionOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003457) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003460) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019815) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0035369) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0071708))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000954 obo:CL_0000955) # Class: obo:CL_0000955 (pre-B-II cell) @@ -12180,7 +11911,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000955 "pre-BII cell") AnnotationAssertion(rdfs:comment obo:CL_0000955 "pre-B-II cell are also reportedly CD19-positive, CD22-positive, CD38-positive, CD45-positive, and CD48-positive.") AnnotationAssertion(rdfs:label obo:CL_0000955 "pre-B-II cell") EquivalentClasses(obo:CL_0000955 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000006611) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0071707))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000955 obo:CL_0000817) SubClassOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826)) DisjointClasses(obo:CL_0000955 obo:CL_0000956) @@ -12192,7 +11922,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11244048") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000956 "Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label obo:CL_0000956 "pre-B-I cell") EquivalentClasses(obo:CL_0000956 ObjectIntersectionOf(obo:CL_0000817 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003457) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003460) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000006611) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0071707) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001858) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001859))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000956 obo:CL_0000817) SubClassOf(obo:CL_0000956 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000826)) # Class: obo:CL_0000957 (large pre-B-II cell) @@ -12203,7 +11932,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000957 "large pre-BII cell" AnnotationAssertion(rdfs:comment obo:CL_0000957 "Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") AnnotationAssertion(rdfs:label obo:CL_0000957 "large pre-B-II cell") EquivalentClasses(obo:CL_0000957 ObjectIntersectionOf(obo:CL_0000955 ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000003457) ObjectSomeValuesFrom(obo:CL_4030045 obo:PR_000003460) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0046651))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000957 obo:CL_0000955) # Class: obo:CL_0000958 (T1 B cell) @@ -12215,7 +11943,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000958 "transitional stage AnnotationAssertion(rdfs:comment obo:CL_0000958 "T1 B cells are also reportedly CD10-negative/positive??, CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000958 "T1 B cell") EquivalentClasses(obo:CL_0000958 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001338) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000958 obo:CL_0000818) # Class: obo:CL_0000959 (T2 B cell) @@ -12227,7 +11954,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000959 "transitional stage AnnotationAssertion(rdfs:comment obo:CL_0000959 "T2 B cells are also reportedly CD20-positive, CD24-positive, CD38-positive, CD48-positive, CD84-positive, CD150-positive, CD244-negative, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000959 "T2 B cell") EquivalentClasses(obo:CL_0000959 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000959 obo:CL_0000818) SubClassOf(obo:CL_0000959 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000958)) # Class: obo:CL_0000960 (T3 B cell) @@ -12240,7 +11966,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "T3 B-lymphocyte") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000960 "transitional stage 3 B cell") AnnotationAssertion(rdfs:label obo:CL_0000960 "T3 B cell") EquivalentClasses(obo:CL_0000960 ObjectIntersectionOf(obo:CL_0000818 ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0002515) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001318) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001338) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000960 obo:CL_0000818) SubClassOf(obo:CL_0000960 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000959)) # Class: obo:CL_0000961 (Bm1 B cell) @@ -12252,7 +11977,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000961 "Bm1 B-lymphocyte") AnnotationAssertion(rdfs:comment obo:CL_0000961 "These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") AnnotationAssertion(rdfs:label obo:CL_0000961 "Bm1 B cell") EquivalentClasses(obo:CL_0000961 ObjectIntersectionOf(obo:CL_0000843 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000961 obo:CL_0000843) SubClassOf(obo:CL_0000961 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000818)) # Class: obo:CL_0000962 (Bm2 B cell) @@ -12264,7 +11988,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000962 "Bm2 B-lymphocyte") AnnotationAssertion(rdfs:comment obo:CL_0000962 "These cells are also CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") AnnotationAssertion(rdfs:label obo:CL_0000962 "Bm2 B cell") EquivalentClasses(obo:CL_0000962 ObjectIntersectionOf(obo:CL_0000843 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001880))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000962 obo:CL_0000843) SubClassOf(obo:CL_0000962 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000961)) # Class: obo:CL_0000963 (Bm3-delta B cell) @@ -12275,7 +11998,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000963 "Bm3-delta B-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000963 "Bm3-delta B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000963 "Bm3-delta B cell") EquivalentClasses(obo:CL_0000963 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000963 obo:CL_0000844) SubClassOf(obo:CL_0000963 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000965)) # Class: obo:CL_0000964 (Bm2' B cell) @@ -12289,7 +12011,6 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000964 "germinal center f AnnotationAssertion(rdfs:comment obo:CL_0000964 "Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") AnnotationAssertion(rdfs:label obo:CL_0000964 "Bm2' B cell") EquivalentClasses(obo:CL_0000964 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001880) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002634))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000964 obo:CL_0000844) SubClassOf(obo:CL_0000964 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000962)) # Class: obo:CL_0000965 (Bm3 B cell) @@ -12302,7 +12023,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:8006591") oboInOwl:hasRe AnnotationAssertion(rdfs:comment obo:CL_0000965 "Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.") AnnotationAssertion(rdfs:label obo:CL_0000965 "Bm3 B cell") EquivalentClasses(obo:CL_0000965 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000003516) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0016446))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000965 obo:CL_0000844) SubClassOf(obo:CL_0000965 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000964)) # Class: obo:CL_0000966 (Bm4 B cell) @@ -12315,7 +12035,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:17992590") oboInOwl:hasR AnnotationAssertion(rdfs:comment obo:CL_0000966 "Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive.") AnnotationAssertion(rdfs:label obo:CL_0000966 "Bm4 B cell") EquivalentClasses(obo:CL_0000966 ObjectIntersectionOf(obo:CL_0000844 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000003516) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0016446))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000966 obo:CL_0000844) SubClassOf(obo:CL_0000966 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000963)) # Class: obo:CL_0000967 (Bm5 B cell) @@ -12327,7 +12046,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000967 "Bm5 B-lymphocyte") AnnotationAssertion(rdfs:comment obo:CL_0000967 "Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative.") AnnotationAssertion(rdfs:label obo:CL_0000967 "Bm5 B cell") EquivalentClasses(obo:CL_0000967 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0002314) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0016446))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000967 obo:CL_0000787) SubClassOf(obo:CL_0000967 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000966)) # Class: obo:CL_0000968 (Be cell) @@ -12340,7 +12058,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000968 "effector B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000968 "Be cell") EquivalentClasses(obo:CL_0000968 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043370))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000968 obo:CL_0000785) # Class: obo:CL_0000969 (regulatory B cell) @@ -12354,7 +12071,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000969 "regulatory B-lympho AnnotationAssertion(rdfs:comment obo:CL_0000969 "Regulatory B cells reportedly represent 1-2% of the spleen and 7-8% of the peritoneal B220-positive cells in mice. They are also found in the bone marrow, lymph node, and blood of mice. These cells are also reportedly capable of secreting IL-10 and are reportedly CD5-positive, CD21-positive, CD24-positive, CD93-negative, B220-positive, IgM-positive, and IgD-positive.") AnnotationAssertion(rdfs:label obo:CL_0000969 "regulatory B cell") EquivalentClasses(obo:CL_0000969 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002028) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050777))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000969 obo:CL_0000785) # Class: obo:CL_0000970 (unswitched memory B cell) @@ -12367,7 +12083,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000970 "unswitched memory B AnnotationAssertion(rdfs:comment obo:CL_0000970 "This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000970 "unswitched memory B cell") EquivalentClasses(obo:CL_0000970 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071742) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071745) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738) ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000970 obo:CL_0000787) SubClassOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980)) # Class: obo:CL_0000971 (IgM memory B cell) @@ -12394,7 +12109,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000972 "class switched memo AnnotationAssertion(rdfs:comment obo:CL_0000972 "Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.") AnnotationAssertion(rdfs:label obo:CL_0000972 "class switched memory B cell") EquivalentClasses(obo:CL_0000972 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071753) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0045190))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000972 obo:CL_0000787) SubClassOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000970)) # Class: obo:CL_0000973 (IgA memory B cell) @@ -12410,14 +12124,12 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000973 "memory IgA B-lympho AnnotationAssertion(rdfs:comment obo:CL_0000973 "IgA memory B cell are also reportedly RORalpha-positive.") AnnotationAssertion(rdfs:label obo:CL_0000973 "IgA memory B cell") EquivalentClasses(obo:CL_0000973 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071745))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000973 obo:CL_0000972) # Class: obo:CL_0000974 (long lived plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:9780781765190") Annotation(oboInOwl:hasDbXref "PMID:16014527") obo:IAO_0000115 obo:CL_0000974 "A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow.") AnnotationAssertion(rdfs:label obo:CL_0000974 "long lived plasma cell") EquivalentClasses(obo:CL_0000974 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0019814) ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001208) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001002))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000974 obo:CL_0000786) SubClassOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000975)) # Class: obo:CL_0000975 (short lived plasma cell) @@ -12425,7 +12137,6 @@ SubClassOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000975)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16014527") obo:IAO_0000115 obo:CL_0000975 "A fully differentiated plasma cell that lives for months.") AnnotationAssertion(rdfs:label obo:CL_0000975 "short lived plasma cell") EquivalentClasses(obo:CL_0000975 ObjectIntersectionOf(obo:CL_0000786 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001604))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000975 obo:CL_0000786) SubClassOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980)) # Class: obo:CL_0000976 (IgA short lived plasma cell) @@ -12433,21 +12144,18 @@ SubClassOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000980)) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000976 "A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system.") AnnotationAssertion(rdfs:label obo:CL_0000976 "IgA short lived plasma cell") EquivalentClasses(obo:CL_0000976 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000976 obo:CL_0000975) # Class: obo:CL_0000977 (IgG short lived plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000977 "A short lived plasma cell that secretes IgG.") AnnotationAssertion(rdfs:label obo:CL_0000977 "IgG short lived plasma cell") EquivalentClasses(obo:CL_0000977 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000977 obo:CL_0000975) # Class: obo:CL_0000978 (IgM short lived plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000978 "A short lived plasma cell that secretes IgM.") AnnotationAssertion(rdfs:label obo:CL_0000978 "IgM short lived plasma cell") EquivalentClasses(obo:CL_0000978 ObjectIntersectionOf(obo:CL_0000975 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000978 obo:CL_0000975) # Class: obo:CL_0000979 (IgG memory B cell) @@ -12461,7 +12169,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B-cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000979 "memory IgG B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000979 "IgG memory B cell") EquivalentClasses(obo:CL_0000979 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071735))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000979 obo:CL_0000972) # Class: obo:CL_0000980 (plasmablast) @@ -12472,7 +12179,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000980 "CD27-positive, CD38 AnnotationAssertion(rdfs:comment obo:CL_0000980 "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative.") AnnotationAssertion(rdfs:label obo:CL_0000980 "plasmablast") EquivalentClasses(obo:CL_0000980 ObjectIntersectionOf(obo:CL_0000785 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001935) ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0042571) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001963))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000980 obo:CL_0000785) SubClassOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000785)) # Class: obo:CL_0000981 (double negative memory B cell) @@ -12487,49 +12193,42 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "double negative mem AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000981 "double negative memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0000981 "double negative memory B cell") EquivalentClasses(obo:CL_0000981 ObjectIntersectionOf(obo:CL_0000787 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000981 obo:CL_0000787) # Class: obo:CL_0000982 (IgG plasmablast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000982 "A plasmablast that secretes IgG.") AnnotationAssertion(rdfs:label obo:CL_0000982 "IgG plasmablast") EquivalentClasses(obo:CL_0000982 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000982 obo:CL_0000980) # Class: obo:CL_0000983 (IgM plasmablast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000983 "A plasmablast that secretes IgM.") AnnotationAssertion(rdfs:label obo:CL_0000983 "IgM plasmablast") EquivalentClasses(obo:CL_0000983 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000983 obo:CL_0000980) # Class: obo:CL_0000984 (IgA plasmablast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") obo:IAO_0000115 obo:CL_0000984 "A plasmablast that secretes IgA.") AnnotationAssertion(rdfs:label obo:CL_0000984 "IgA plasmablast") EquivalentClasses(obo:CL_0000984 ObjectIntersectionOf(obo:CL_0000980 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000984 obo:CL_0000980) # Class: obo:CL_0000985 (IgG plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000985 "A fully differentiated plasma cell that secretes IgG.") AnnotationAssertion(rdfs:label obo:CL_0000985 "IgG plasma cell") EquivalentClasses(obo:CL_0000985 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071736))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000985 obo:CL_0000974) # Class: obo:CL_0000986 (IgM plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000986 "A fully differentiated plasma cell that secretes IgM.") AnnotationAssertion(rdfs:label obo:CL_0000986 "IgM plasma cell") EquivalentClasses(obo:CL_0000986 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071754))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000986 obo:CL_0000974) # Class: obo:CL_0000987 (IgA plasma cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:msz") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "ISBN:781735149") obo:IAO_0000115 obo:CL_0000987 "A fully differentiated plasma cell that secretes IgA.") AnnotationAssertion(rdfs:label obo:CL_0000987 "IgA plasma cell") EquivalentClasses(obo:CL_0000987 ObjectIntersectionOf(obo:CL_0000974 ObjectSomeValuesFrom(obo:RO_0003000 obo:GO_0071746))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000987 obo:CL_0000974) # Class: obo:CL_0000988 (hematopoietic cell) @@ -12550,7 +12249,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000989 "Originally described in the dendritic cell ontology (DC_CL:0000001)(PMID:19243617). These cells are CD281-positive (TLR1), CD282-positive (TLR2), CD285-positive (TLR5), CD286-positive (TLR6), and CD288-positive (TLR8).") AnnotationAssertion(rdfs:label obo:CL_0000989 "CD11c-low plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000989 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002978) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001013))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000989 obo:CL_0000784) # Class: obo:CL_0000990 (conventional dendritic cell) @@ -12565,7 +12263,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000990 "type 1 DC") AnnotationAssertion(rdfs:comment obo:CL_0000990 "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive.") AnnotationAssertion(rdfs:label obo:CL_0000990 "conventional dendritic cell") EquivalentClasses(obo:CL_0000990 ObjectIntersectionOf(obo:CL_0000451 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001013))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000990 obo:CL_0000451) # Class: obo:CL_0000991 (CD11c-negative plasmacytoid dendritic cell) @@ -12574,7 +12271,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000991 "CD303-positive dend AnnotationAssertion(rdfs:comment obo:CL_0000991 "Originally described in the dendritic cell ontology (DC_CL:0000004)(PMID:19243617). These cells are CD281-positive (TLR1), CD286-positive (TLR6), and CD290-positive (TLR10).") AnnotationAssertion(rdfs:label obo:CL_0000991 "CD11c-negative plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000991 ObjectIntersectionOf(obo:CL_0000784 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001292) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001398) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032606))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000991 obo:CL_0000784) # Class: obo:CL_0000992 (immature CD11c-low plasmacytoid dendritic cell) @@ -12582,7 +12278,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000992 "Originally described in the dendritic cell ontology (DC_CL:0000006)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000992 "immature CD11c-low plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000992 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000992 obo:CL_0000989) SubClassOf(obo:CL_0000992 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029)) # Class: obo:CL_0000993 (mature CD11c-low plasmacytoid dendritic cell) @@ -12591,7 +12286,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000993 "Originally described in the dendritic cell ontology (DC_CL:0000007)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000993 "mature CD11c-low plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000993 ObjectIntersectionOf(obo:CL_0000989 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000993 obo:CL_0000989) SubClassOf(obo:CL_0000993 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000992)) # Class: obo:CL_0000994 (immature CD11c-negative plasmacytoid dendritic cell) @@ -12600,7 +12294,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000994 "Originally described in the dendritic cell ontology (DC_CL:0000008)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000994 "immature CD11c-negative plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000994 ObjectIntersectionOf(obo:CL_0000991 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001438) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000994 obo:CL_0000991) SubClassOf(obo:CL_0000994 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000995)) # Class: obo:CL_0000995 (CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor) @@ -12617,7 +12310,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000996 "Originally described in the dendritic cell ontology (DC_CL:0000009)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000996 "mature CD11c-negative plasmacytoid dendritic cell") EquivalentClasses(obo:CL_0000996 ObjectIntersectionOf(obo:CL_0000991 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000996 obo:CL_0000991) SubClassOf(obo:CL_0000996 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000994)) # Class: obo:CL_0000997 (immature CD8_alpha-negative CD11b-positive dendritic cell) @@ -12626,7 +12318,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0000997 "Originally described in the dendritic cell ontology (DC_CL:0000010)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000997 "immature CD8_alpha-negative CD11b-positive dendritic cell") EquivalentClasses(obo:CL_0000997 ObjectIntersectionOf(obo:CL_0000999 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000997 obo:CL_0000999) SubClassOf(obo:CL_0000997 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010)) # Class: obo:CL_0000998 (CD8_alpha-negative CD11b-negative dendritic cell) @@ -12637,7 +12328,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000998 "triple negative den AnnotationAssertion(rdfs:comment obo:CL_0000998 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000011)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0000998 "CD8_alpha-negative CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0000998 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002474))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000998 obo:CL_0000990) SubClassOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010)) # Class: obo:CL_0000999 (CD4-positive CD11b-positive dendritic cell) @@ -12657,7 +12347,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001000 "DC.8+") AnnotationAssertion(rdfs:comment obo:CL_0001000 "Cells are defined as having a disposition to secreting inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000013)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001000 "CD8_alpha-positive CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0001000 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042590) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050729))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001000 obo:CL_0000990) SubClassOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010)) # Class: obo:CL_0001001 (immature CD8_alpha-negative CD11b-negative dendritic cell) @@ -12666,7 +12355,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001001 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000014)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001001 "immature CD8_alpha-negative CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0001001 ObjectIntersectionOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001001 obo:CL_0000998) SubClassOf(obo:CL_0001001 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010)) # Class: obo:CL_0001002 (mature CD8_alpha-negative CD11b-negative dendritic cell) @@ -12675,7 +12363,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001002 "These markers are associated with mouse cells. Defined as having a disposition to secretion of anti-inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000015)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001002 "mature CD8_alpha-negative CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0001002 ObjectIntersectionOf(obo:CL_0000998 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001002 obo:CL_0000998) SubClassOf(obo:CL_0001002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001001)) # Class: obo:CL_0001003 (mature CD8_alpha-negative CD11b-positive dendritic cell) @@ -12684,7 +12371,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001003 "Originally described in the dendritic cell ontology (DC_CL:0000016)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001003 "mature CD8_alpha-negative CD11b-positive dendritic cell") EquivalentClasses(obo:CL_0001003 ObjectIntersectionOf(obo:CL_0000999 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001003 obo:CL_0000999) SubClassOf(obo:CL_0001003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000997)) # Class: obo:CL_0001004 (immature CD8_alpha-positive CD11b-negative dendritic cell) @@ -12693,7 +12379,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001004 "Originally described in the dendritic cell ontology (DC_CL:0000017)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001004 "immature CD8_alpha-positive CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0001004 ObjectIntersectionOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001004 obo:CL_0001000) SubClassOf(obo:CL_0001004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002010)) # Class: obo:CL_0001005 (mature CD8_alpha-positive CD11b-negative dendritic cell) @@ -12702,7 +12387,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001005 "Originally described in the dendritic cell ontology (DC_CL:0000018)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001005 "mature CD8_alpha-positive CD11b-negative dendritic cell") EquivalentClasses(obo:CL_0001005 ObjectIntersectionOf(obo:CL_0001000 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001005 obo:CL_0001000) SubClassOf(obo:CL_0001005 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001004)) # Class: obo:CL_0001006 (dermal dendritic cell) @@ -12712,7 +12396,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0001006 "BTO:0004812") AnnotationAssertion(rdfs:comment obo:CL_0001006 "Originally described in the dendritic cell ontology (DC_CL:0000019)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD288-positive (TLR8), and CD289-positive (TLR9).") AnnotationAssertion(rdfs:label obo:CL_0001006 "dermal dendritic cell") EquivalentClasses(obo:CL_0001006 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002067) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001006 obo:CL_0000990) # Class: obo:CL_0001007 (interstitial dendritic cell) @@ -12720,7 +12403,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001007 "Originally described in the dendritic cell ontology (DC_CL:0000020)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10).") AnnotationAssertion(rdfs:label obo:CL_0001007 "interstitial dendritic cell") EquivalentClasses(obo:CL_0001007 ObjectIntersectionOf(obo:CL_0000990 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001300) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001905) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002025) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002972))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001007 obo:CL_0000990) # Class: obo:CL_0001008 (Kit and Sca1-positive hematopoietic stem cell) @@ -12730,7 +12412,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001008 "Sca1-positive hemat AnnotationAssertion(rdfs:comment obo:CL_0001008 "Cell markers are associated with mouse hematopoietic stem cell. Originally described in the dendritic cell ontology (DC_CL:0000043)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001008 "Kit and Sca1-positive hematopoietic stem cell") EquivalentClasses(obo:CL_0001008 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001308) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001896) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002977) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001833) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002979))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001008 obo:CL_0000037) DisjointClasses(obo:CL_0001008 obo:CL_0001024) # Class: obo:CL_0001009 (immature dermal dendritic cell) @@ -12739,7 +12420,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001009 "Originally described in the dendritic cell ontology (DC_CL:0000022)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001009 "immature dermal dendritic cell") EquivalentClasses(obo:CL_0001009 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001009 obo:CL_0001006) SubClassOf(obo:CL_0001009 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029)) # Class: obo:CL_0001010 (mature dermal dendritic cell) @@ -12748,7 +12428,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001010 "Originally described in the dendritic cell ontology (DC_CL:0000023)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001010 "mature dermal dendritic cell") EquivalentClasses(obo:CL_0001010 ObjectIntersectionOf(obo:CL_0001006 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001010 obo:CL_0001006) SubClassOf(obo:CL_0001010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001009)) # Class: obo:CL_0001011 (immature interstitial dendritic cell) @@ -12757,7 +12436,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001011 "Originally described in the dendritic cell ontology (DC_CL:0000024)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001011 "immature interstitial dendritic cell") EquivalentClasses(obo:CL_0001011 ObjectIntersectionOf(obo:CL_0001007 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001011 obo:CL_0001007) SubClassOf(obo:CL_0001011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001012)) # Class: obo:CL_0001012 (CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor) @@ -12773,7 +12451,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001013 "Originally described in the dendritic cell ontology (DC_CL:0000025)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001013 "mature interstitial dendritic cell") EquivalentClasses(obo:CL_0001013 ObjectIntersectionOf(obo:CL_0001007 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001013 obo:CL_0001007) SubClassOf(obo:CL_0001013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001011)) # Class: obo:CL_0001014 (CD1a-positive Langerhans cell) @@ -12783,7 +12460,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001014 "CD1a-LC") AnnotationAssertion(rdfs:comment obo:CL_0001014 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000026)(PMID:19243617). These cells are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD286-positive (TLR6), CD287-positive (TLR7), and CD290-positive (TLR10). When activated, these cells are capable of producing IL-6, IL-8, and IL-15.") AnnotationAssertion(rdfs:label obo:CL_0001014 "CD1a-positive Langerhans cell") EquivalentClasses(obo:CL_0001014 ObjectIntersectionOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001447) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002025))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001014 obo:CL_0000453) # Class: obo:CL_0001015 (CD8_alpha-low Langerhans cell) @@ -12791,7 +12467,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001015 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000027)(PMID:19243617). They are also CD205-high, CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD285-positive (TLR5), CD286-positive (TLR6), and CD289-positive (TLR9).") AnnotationAssertion(rdfs:label obo:CL_0001015 "CD8_alpha-low Langerhans cell") EquivalentClasses(obo:CL_0001015 ObjectIntersectionOf(obo:CL_0000453 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001026) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001084))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001015 obo:CL_0000453) # Class: obo:CL_0001016 (immature CD1a-positive Langerhans cell) @@ -12799,7 +12474,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001016 "Originally described in the dendritic cell ontology (DC_CL:0000028)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001016 "immature CD1a-positive Langerhans cell") EquivalentClasses(obo:CL_0001016 ObjectIntersectionOf(obo:CL_0001014 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001016 obo:CL_0001014) # Class: obo:CL_0001017 (mature CD1a-positive Langerhans cell) @@ -12807,7 +12481,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001017 "Originally described in the dendritic cell ontology (DC_CL:0000029)(PMID:19243617). When activated, these cells produce IL-6, IL-8, and IL-15.") AnnotationAssertion(rdfs:label obo:CL_0001017 "mature CD1a-positive Langerhans cell") EquivalentClasses(obo:CL_0001017 ObjectIntersectionOf(obo:CL_0001014 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001017 obo:CL_0001014) SubClassOf(obo:CL_0001017 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001016)) # Class: obo:CL_0001018 (immature CD8_alpha-low Langerhans cell) @@ -12816,7 +12489,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001018 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000030)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001018 "immature CD8_alpha-low Langerhans cell") EquivalentClasses(obo:CL_0001018 ObjectIntersectionOf(obo:CL_0001015 ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001018 obo:CL_0001015) SubClassOf(obo:CL_0001018 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001019)) # Class: obo:CL_0001019 (CD115-positive monocyte OR common dendritic progenitor) @@ -12832,7 +12504,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:amm") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001020 "These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000031)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001020 "mature CD8_alpha-low Langerhans cell") EquivalentClasses(obo:CL_0001020 ObjectIntersectionOf(obo:CL_0001015 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001310) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0042613) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001412) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001438))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001020 obo:CL_0001015) SubClassOf(obo:CL_0001020 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001018)) # Class: obo:CL_0001021 (CD34-positive, CD38-positive common lymphoid progenitor) @@ -12844,7 +12515,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001021 "CD10-positive commo AnnotationAssertion(rdfs:comment obo:CL_0001021 "These markers are associated with human common lymphoid progenitors. Originally described in the dendritic cell ontology (DC_CL:0000032)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001021 "CD34-positive, CD38-positive common lymphoid progenitor") EquivalentClasses(obo:CL_0001021 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001898))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001021 obo:CL_0000051) SubClassOf(obo:CL_0001021 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002043)) DisjointClasses(obo:CL_0001021 obo:CL_0001025) @@ -12854,7 +12524,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:add") Annotation(oboInOwl AnnotationAssertion(rdfs:comment obo:CL_0001022 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000033)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001022 "CD115-positive monocyte") EquivalentClasses(obo:CL_0001022 ObjectIntersectionOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001012) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001022 obo:CL_0000576) SubClassOf(obo:CL_0001022 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002001)) # Class: obo:CL_0001023 (Kit-positive, CD34-positive common myeloid progenitor) @@ -12864,7 +12533,6 @@ AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0001023 "CD117-positive comm AnnotationAssertion(rdfs:comment obo:CL_0001023 "Markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000034)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001023 "Kit-positive, CD34-positive common myeloid progenitor") EquivalentClasses(obo:CL_0001023 ObjectIntersectionOf(obo:CL_0001059 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0033001) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001481))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001023 obo:CL_0001059) SubClassOf(obo:CL_0001023 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002035)) DisjointClasses(obo:CL_0001023 obo:CL_0001026) @@ -12876,7 +12544,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16140871") oboInOwl:hasE AnnotationAssertion(rdfs:comment obo:CL_0001024 "Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001024 "CD34-positive, CD38-negative hematopoietic stem cell") EquivalentClasses(obo:CL_0001024 ObjectIntersectionOf(obo:CL_0000037 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001483) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001892) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001786) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001809) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001843))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001024 obo:CL_0000037) # Class: obo:CL_0001025 (Kit-positive, Sca1-positive common lymphoid progenitor) @@ -12887,7 +12554,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001025 "CD217-positive comm AnnotationAssertion(rdfs:comment obo:CL_0001025 "Markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0001025 "Kit-positive, Sca1-positive common lymphoid progenitor") EquivalentClasses(obo:CL_0001025 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001014) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002037) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002979))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001025 obo:CL_0000051) SubClassOf(obo:CL_0001025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000936)) # Class: obo:CL_0001026 (CD34-positive, CD38-positive common myeloid progenitor) @@ -12907,7 +12573,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001027 "CD7-negative lympho AnnotationAssertion(rdfs:comment obo:CL_0001027 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000039)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001027 "CD7-negative lymphoid progenitor cell") EquivalentClasses(obo:CL_0001027 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001836) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001027 obo:CL_0000051) SubClassOf(obo:CL_0001027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001021)) # Class: obo:CL_0001028 (CD7-positive lymphoid progenitor cell) @@ -12917,7 +12582,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001028 "CD7-positive lympho AnnotationAssertion(rdfs:comment obo:CL_0001028 "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001028 "CD7-positive lymphoid progenitor cell") EquivalentClasses(obo:CL_0001028 ObjectIntersectionOf(obo:CL_0000051 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001836))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001028 obo:CL_0000051) SubClassOf(obo:CL_0001028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001027)) # Class: obo:CL_0001029 (common dendritic progenitor) @@ -12929,7 +12593,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21219184") oboInOwl:hasE AnnotationAssertion(rdfs:comment obo:CL_0001029 "Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).") AnnotationAssertion(rdfs:label obo:CL_0001029 "common dendritic progenitor") EquivalentClasses(obo:CL_0001029 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001029 obo:CL_0002031) SubClassOf(obo:CL_0001029 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002009)) # Class: obo:CL_0001030 (CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor) @@ -13011,7 +12674,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001041 "CD8-positive, CXCR3 AnnotationAssertion(rdfs:comment obo:CL_0001041 "These cells may be the human equivalent of murine CD8-positive, CD122-positive alpha-beta regulatory T cell. They are also found in the CD45RA-negative and CD62L-positive fraction.") AnnotationAssertion(rdfs:label obo:CL_0001041 "CD8-positive, CXCR3-positive, alpha-beta regulatory T cell") EquivalentClasses(obo:CL_0001041 ObjectIntersectionOf(obo:CL_0000795 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001207) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032613) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032689) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0042130))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001041 obo:CL_0000795) # Class: obo:CL_0001042 (T-helper 22 cell) @@ -13026,7 +12688,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001042 "helper T cell type AnnotationAssertion(rdfs:comment obo:CL_0001042 "TH22 cells are also reportedly CCR4-positive, CCR6-positive, CCR10-positive, CXCR3-negative. TH22 cells are reportedly capable of secreting IL-13.") AnnotationAssertion(rdfs:label obo:CL_0001042 "T-helper 22 cell") EquivalentClasses(obo:CL_0001042 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032626))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001042 obo:CL_0000492) SubClassOf(obo:CL_0001042 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0001043 (activated CD4-positive, alpha-beta T cell, human) @@ -13486,7 +13147,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001203 "CD8-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001203 "CD8-positive, alpha-beta memory T-lymphocyte, CD45RO-positive") AnnotationAssertion(rdfs:label obo:CL_0001203 "CD8-positive, alpha-beta memory T cell, CD45RO-positive") EquivalentClasses(obo:CL_0001203 ObjectIntersectionOf(obo:CL_0000909 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001381))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001203 obo:CL_0000909) SubClassOf(obo:CL_0001203 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000906)) # Class: obo:CL_0001204 (CD4-positive, alpha-beta memory T cell, CD45RO-positive) @@ -13497,7 +13157,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001204 "CD4-positive, alpha AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0001204 "CD4-positive, alpha-beta memory T-lymphocyte, CD45RO-positive") AnnotationAssertion(rdfs:label obo:CL_0001204 "CD4-positive, alpha-beta memory T cell, CD45RO-positive") EquivalentClasses(obo:CL_0001204 ObjectIntersectionOf(obo:CL_0000897 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001380) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001017) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001869) ObjectSomeValuesFrom(obo:RO_0002160 obo:NCBITaxon_9606) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0043379) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001307) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001381))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0001204 obo:CL_0000897) SubClassOf(obo:CL_0001204 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000896)) # Class: obo:CL_0001658 (visual pigment cell (sensu Nematoda and Protostomia)) @@ -13515,7 +13174,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002000 "c- Kit-positive ery AnnotationAssertion(rdfs:comment obo:CL_0002000 "Markers found on mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002000 "Kit-positive erythroid progenitor cell") EquivalentClasses(obo:CL_0002000 ObjectIntersectionOf(obo:CL_0001066 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0033001) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001833) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000009127) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001345) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002000 obo:CL_0001066) SubClassOf(obo:CL_0002000 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002006)) # Class: obo:CL_0002001 (CD34-positive, CD38-positive granulocyte monocyte progenitor) @@ -13526,7 +13184,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002001 "2010-01-13T03:19:22Z" AnnotationAssertion(rdfs:comment obo:CL_0002001 "Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population.") AnnotationAssertion(rdfs:label obo:CL_0002001 "CD34-positive, CD38-positive granulocyte monocyte progenitor") EquivalentClasses(obo:CL_0002001 ObjectIntersectionOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002001 obo:CL_0000557) SubClassOf(obo:CL_0002001 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001026)) # Class: obo:CL_0002002 (Kit-positive granulocyte monocyte progenitor) @@ -13537,7 +13194,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002002 "2010-01-13T03:19:28Z" AnnotationAssertion(rdfs:comment obo:CL_0002002 "Markers are found on mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002002 "Kit-positive granulocyte monocyte progenitor") EquivalentClasses(obo:CL_0002002 ObjectIntersectionOf(obo:CL_0000557 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001206) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001843) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015015 obo:GO_0033001) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001479))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002002 obo:CL_0000557) SubClassOf(obo:CL_0002002 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001023)) # Class: obo:CL_0002003 (CD34-positive, GlyA-negative erythroid progenitor cell) @@ -13549,7 +13205,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002003 "FMA:83517") AnnotationAssertion(rdfs:comment obo:CL_0002003 "Cell markers associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002003 "CD34-positive, GlyA-negative erythroid progenitor cell") EquivalentClasses(obo:CL_0002003 ObjectIntersectionOf(obo:CL_0001066 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002003 obo:CL_0001066) SubClassOf(obo:CL_0002003 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002005)) # Class: obo:CL_0002004 (CD34-negative, GlyA-negative proerythroblast) @@ -13560,7 +13215,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002004 "2010-04-26T10:31:50Z" AnnotationAssertion(rdfs:comment obo:CL_0002004 "Cell surface markers are associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002004 "CD34-negative, GlyA-negative proerythroblast") EquivalentClasses(obo:CL_0002004 ObjectIntersectionOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001460))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002004 obo:CL_0000547) SubClassOf(obo:CL_0002004 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002003)) # Class: obo:CL_0002005 (CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell) @@ -13571,7 +13225,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002005 "2010-01-13T03:43:10Z" AnnotationAssertion(rdfs:comment obo:CL_0002005 "Markers are associated with human cell type.") AnnotationAssertion(rdfs:label obo:CL_0002005 "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell") EquivalentClasses(obo:CL_0002005 ObjectIntersectionOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001015) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001865) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002005 obo:CL_0000050) # Class: obo:CL_0002006 (Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell) @@ -13581,7 +13234,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002006 "2010-01-13T03:43:12Z" AnnotationAssertion(rdfs:comment obo:CL_0002006 "Markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002006 "Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell") EquivalentClasses(obo:CL_0002006 ObjectIntersectionOf(obo:CL_0000050 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001479) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001843) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0015016 obo:GO_0033001))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002006 obo:CL_0000050) # Class: obo:CL_0002007 (Kit-low, CD34-positive eosinophil progenitor cell) @@ -13591,7 +13243,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002007 "2010-01-14T03:25:15Z" AnnotationAssertion(rdfs:comment obo:CL_0002007 "Markers are found on mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002007 "Kit-low, CD34-positive eosinophil progenitor cell") EquivalentClasses(obo:CL_0002007 ObjectIntersectionOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002007 obo:CL_0000611) SubClassOf(obo:CL_0002007 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002002)) # Class: obo:CL_0002008 (CD34-positive, CD38-positive eosinophil progenitor cell) @@ -13602,7 +13253,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002008 "2010-01-14T03:25:17Z" AnnotationAssertion(rdfs:comment obo:CL_0002008 "Markers are associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002008 "CD34-positive, CD38-positive eosinophil progenitor cell") EquivalentClasses(obo:CL_0002008 ObjectIntersectionOf(obo:CL_0000611 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001015) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001865))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002008 obo:CL_0000611) SubClassOf(obo:CL_0002008 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002001)) # Class: obo:CL_0002009 (macrophage dendritic cell progenitor) @@ -13613,7 +13263,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002009 "2010-01-19T02:51:58Z" AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002009 "MDP") AnnotationAssertion(rdfs:label obo:CL_0002009 "macrophage dendritic cell progenitor") EquivalentClasses(obo:CL_0002009 ObjectIntersectionOf(obo:CL_0002032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030224) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002009 obo:CL_0002032) SubClassOf(obo:CL_0002009 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557)) # Class: obo:CL_0002010 (pre-conventional dendritic cell) @@ -13622,7 +13271,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo AnnotationAssertion(oboInOwl:creation_date obo:CL_0002010 "2010-01-19T03:39:30Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_0002010 "pre-conventional dendritic cell") EquivalentClasses(obo:CL_0002010 ObjectIntersectionOf(obo:CL_0002031 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001004) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001012) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001083) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001084) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001839) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001889) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002978) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001013) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001968) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002010 obo:CL_0002031) SubClassOf(obo:CL_0002010 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0001029)) # Class: obo:CL_0002011 (Kit-positive macrophage dendritic cell progenitor) @@ -13634,7 +13282,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002011 "murine MDP") AnnotationAssertion(rdfs:comment obo:CL_0002011 "Markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002011 "Kit-positive macrophage dendritic cell progenitor") EquivalentClasses(obo:CL_0002011 ObjectIntersectionOf(obo:CL_0002009 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001206) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002001) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002065))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002011 obo:CL_0002009) SubClassOf(obo:CL_0002011 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002002)) # Class: obo:CL_0002012 (Kit-low proerythroblast) @@ -13645,7 +13292,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002012 "2010-04-26T10:31:56Z" AnnotationAssertion(rdfs:comment obo:CL_0002012 "Markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002012 "Kit-low proerythroblast") EquivalentClasses(obo:CL_0002012 ObjectIntersectionOf(obo:CL_0000547 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000002065))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002012 obo:CL_0000547) SubClassOf(obo:CL_0002012 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002000)) # Class: obo:CL_0002013 (GlyA-positive basophilic erythroblast) @@ -13656,7 +13302,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002013 "2010-04-26T10:41:15Z" AnnotationAssertion(rdfs:comment obo:CL_0002013 "Markers are associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002013 "GlyA-positive basophilic erythroblast") EquivalentClasses(obo:CL_0002013 ObjectIntersectionOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002013 obo:CL_0000549) SubClassOf(obo:CL_0002013 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002004)) # Class: obo:CL_0002014 (Kit-negative, Ly-76 high basophilic erythroblast) @@ -13667,7 +13312,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002014 "2010-04-26T10:41:22Z" AnnotationAssertion(rdfs:comment obo:CL_0002014 "Cell surface markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002014 "Kit-negative, Ly-76 high basophilic erythroblast") EquivalentClasses(obo:CL_0002014 ObjectIntersectionOf(obo:CL_0000549 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002014 obo:CL_0000549) SubClassOf(obo:CL_0002014 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002012)) # Class: obo:CL_0002015 (Kit-negative, Ly-76 high polychromatophilic erythroblast) @@ -13678,7 +13322,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002015 "2010-04-26T10:53:11Z" AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0002015 "late basophilic and polychromatophilic erythroblast") AnnotationAssertion(rdfs:label obo:CL_0002015 "Kit-negative, Ly-76 high polychromatophilic erythroblast") EquivalentClasses(obo:CL_0002015 ObjectIntersectionOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002015 obo:CL_0000550) SubClassOf(obo:CL_0002015 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002014)) # Class: obo:CL_0002016 (CD71-low, GlyA-positive polychromatic erythroblast) @@ -13689,7 +13332,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002016 "2010-04-26T10:53:16Z" AnnotationAssertion(rdfs:comment obo:CL_0002016 "Cell surface markers are associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002016 "CD71-low, GlyA-positive polychromatic erythroblast") EquivalentClasses(obo:CL_0002016 ObjectIntersectionOf(obo:CL_0000550 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001945))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002016 obo:CL_0000550) SubClassOf(obo:CL_0002016 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002013)) # Class: obo:CL_0002017 (Kit-negative, Ly-76 high orthochromatophilic erythroblasts) @@ -13700,7 +13342,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002017 "2010-04-26T11:04:15Z" AnnotationAssertion(rdfs:comment obo:CL_0002017 "Cell surface markers associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002017 "Kit-negative, Ly-76 high orthochromatophilic erythroblasts") EquivalentClasses(obo:CL_0002017 ObjectIntersectionOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002065) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001945))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002017 obo:CL_0000552) SubClassOf(obo:CL_0002017 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002015)) # Class: obo:CL_0002018 (CD71-negative, GlyA-positive orthochromatic erythroblast) @@ -13711,7 +13352,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002018 "2010-04-26T11:04:21Z" AnnotationAssertion(rdfs:comment obo:CL_0002018 "Markers associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002018 "CD71-negative, GlyA-positive orthochromatic erythroblast") EquivalentClasses(obo:CL_0002018 ObjectIntersectionOf(obo:CL_0000552 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001945) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002018 obo:CL_0000552) SubClassOf(obo:CL_0002018 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002016)) # Class: obo:CL_0002019 (Ly-76 high reticulocyte) @@ -13722,7 +13362,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002019 "2010-04-26T11:37:00Z" AnnotationAssertion(rdfs:comment obo:CL_0002019 "Marker associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002019 "Ly-76 high reticulocyte") EquivalentClasses(obo:CL_0002019 ObjectIntersectionOf(obo:CL_0002422 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002019 obo:CL_0002422) SubClassOf(obo:CL_0002019 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002017)) # Class: obo:CL_0002020 (GlyA-positive reticulocytes) @@ -13733,7 +13372,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002020 "2010-04-26T11:48:25Z" AnnotationAssertion(rdfs:comment obo:CL_0002020 "Markers is associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002020 "GlyA-positive reticulocytes") EquivalentClasses(obo:CL_0002020 ObjectIntersectionOf(obo:CL_0002422 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002020 obo:CL_0002422) SubClassOf(obo:CL_0002020 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002018)) # Class: obo:CL_0002021 (GlyA-positive erythrocyte) @@ -13744,7 +13382,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002021 "2010-04-26T11:51:22Z" AnnotationAssertion(rdfs:comment obo:CL_0002021 "Marker is associated with human cell types.") AnnotationAssertion(rdfs:label obo:CL_0002021 "GlyA-positive erythrocyte") EquivalentClasses(obo:CL_0002021 ObjectIntersectionOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001460))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002021 obo:CL_0000595) SubClassOf(obo:CL_0002021 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002020)) # Class: obo:CL_0002022 (Ly-76 high positive erythrocyte) @@ -13755,7 +13392,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002022 "2010-04-26T11:51:27Z" AnnotationAssertion(rdfs:comment obo:CL_0002022 "Marker is associated with mouse cell types.") AnnotationAssertion(rdfs:label obo:CL_0002022 "Ly-76 high positive erythrocyte") EquivalentClasses(obo:CL_0002022 ObjectIntersectionOf(obo:CL_0000595 ObjectSomeValuesFrom(obo:RO_0015015 obo:PR_000002981))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002022 obo:CL_0000595) SubClassOf(obo:CL_0002022 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002019)) # Class: obo:CL_0002023 (CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell) @@ -13766,7 +13402,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002023 "2010-04-26T02:39:09Z" AnnotationAssertion(rdfs:comment obo:CL_0002023 "Markers are associated with human cell type.") AnnotationAssertion(rdfs:label obo:CL_0002023 "CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell") EquivalentClasses(obo:CL_0002023 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002023 obo:CL_0000553) SubClassOf(obo:CL_0002023 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002025)) # Class: obo:CL_0002024 (Kit-positive megakaryocyte progenitor cell) @@ -13777,7 +13412,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002024 "2010-04-26T02:39:15Z" AnnotationAssertion(rdfs:comment obo:CL_0002024 "Markers are associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002024 "Kit-positive megakaryocyte progenitor cell") EquivalentClasses(obo:CL_0002024 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001833) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001869) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000002979) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002065) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001479) ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001483))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002024 obo:CL_0000553) SubClassOf(obo:CL_0002024 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002006)) # Class: obo:CL_0002025 (CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell) @@ -13788,7 +13422,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002025 "2010-04-26T03:52:47Z" AnnotationAssertion(rdfs:comment obo:CL_0002025 "Markers are commonly associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002025 "CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell") EquivalentClasses(obo:CL_0002025 ObjectIntersectionOf(obo:CL_0000553 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002025 obo:CL_0000553) SubClassOf(obo:CL_0002025 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002005)) # Class: obo:CL_0002026 (CD34-negative, CD41-positive, CD42-positive megakaryocyte cell) @@ -13799,7 +13432,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002026 "2010-04-26T03:59:22Z" AnnotationAssertion(rdfs:comment obo:CL_0002026 "Markers are commonly associated with human cells.") AnnotationAssertion(rdfs:label obo:CL_0002026 "CD34-negative, CD41-positive, CD42-positive megakaryocyte cell") EquivalentClasses(obo:CL_0002026 ObjectIntersectionOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001907) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002026 obo:CL_0000556) SubClassOf(obo:CL_0002026 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002023)) # Class: obo:CL_0002027 (CD9-positive, CD41-positive megakaryocyte cell) @@ -13810,7 +13442,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002027 "2010-04-27T10:39:07Z" AnnotationAssertion(rdfs:comment obo:CL_0002027 "Markers are commonly associated with mouse cells.") AnnotationAssertion(rdfs:label obo:CL_0002027 "CD9-positive, CD41-positive megakaryocyte cell") EquivalentClasses(obo:CL_0002027 ObjectIntersectionOf(obo:CL_0000556 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000005178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000009127))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002027 obo:CL_0000556) SubClassOf(obo:CL_0002027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002024)) # Class: obo:CL_0002028 (basophil mast progenitor cell) @@ -13822,7 +13453,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002028 "BMCP") AnnotationAssertion(rdfs:comment obo:CL_0002028 "There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low.") AnnotationAssertion(rdfs:label obo:CL_0002028 "basophil mast progenitor cell") EquivalentClasses(obo:CL_0002028 ObjectIntersectionOf(obo:CL_0000839 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000005307) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007857) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007858) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000007431) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000016401) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001867) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030221) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0060374))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002028 obo:CL_0000839) SubClassOf(obo:CL_0002028 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000557)) # Class: obo:CL_0002029 (Fc-epsilon RIalpha-low mast cell progenitor) @@ -13832,7 +13462,6 @@ AnnotationAssertion(terms:contributor obo:CL_0002029 ) AnnotationAssertion(oboInOwl:creation_date obo:CL_0002060 "2010-06-22T10:46:12Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_0002060 "melanophage") -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002060 obo:CL_0000864) SubClassOf(obo:CL_0002060 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002097)) # Class: obo:CL_0002061 (T-helper 9 cell) @@ -14203,7 +13801,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002061 "T(H)-9 cell") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:18931678") oboInOwl:hasExactSynonym obo:CL_0002061 "Th9") AnnotationAssertion(rdfs:label obo:CL_0002061 "T-helper 9 cell") EquivalentClasses(obo:CL_0002061 ObjectIntersectionOf(obo:CL_0000492 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000008982) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002215) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032638))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002061 obo:CL_0000492) # Class: obo:CL_0002062 (pulmonary alveolar type 1 cell) @@ -14265,8 +13862,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002064 "FMA:63032") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002064 "acinar cell of pancreas") AnnotationAssertion(rdfs:label obo:CL_0002064 "pancreatic acinar cell") EquivalentClasses(obo:CL_0002064 ObjectIntersectionOf(obo:CL_0000622 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001263))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002064 obo:CL_0000083) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002064 obo:CL_0000622) SubClassOf(obo:CL_0002064 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042589)) # Class: obo:CL_0002065 (obo:CL_0002065) @@ -14347,7 +13942,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002071 "columnar cell of th AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002071 "vacuolar absorptive cell") AnnotationAssertion(rdfs:label obo:CL_0002071 "enterocyte of epithelium of large intestine") EquivalentClasses(obo:CL_0002071 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001278))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002071 obo:CL_0002253) # Class: obo:CL_0002072 (nodal myocyte) @@ -14429,7 +14023,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002079 "FMA:63099") AnnotationAssertion(rdfs:label obo:CL_0002079 "pancreatic ductal cell") EquivalentClasses(obo:CL_0002079 ObjectIntersectionOf(obo:CL_0000083 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001064) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015106))) SubClassOf(obo:CL_0002079 obo:CL_0000069) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002079 obo:CL_0000083) # Class: obo:CL_0002080 (pancreatic centro-acinar cell) @@ -14441,7 +14034,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002080 "centroacinar cell o AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002080 "pancreatic centroacinar cell") AnnotationAssertion(rdfs:label obo:CL_0002080 "pancreatic centro-acinar cell") EquivalentClasses(obo:CL_0002080 ObjectIntersectionOf(obo:CL_0000083 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001263) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0015106))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002080 obo:CL_0000083) # Class: obo:CL_0002081 (type II cell of carotid body) @@ -14465,7 +14057,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002082 "adrenergic chromaff AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002082 "epiniphrine secreting cell of the adrenal medulla") AnnotationAssertion(rdfs:label obo:CL_0002082 "type II cell of adrenal medulla") EquivalentClasses(obo:CL_0002082 ObjectIntersectionOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048242))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002082 obo:CL_0000336) # Class: obo:CL_0002083 (type I cell of adrenal medulla) @@ -14476,7 +14067,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002083 "FMA:69321") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002083 "noradrenergic chromaffin cell") AnnotationAssertion(rdfs:label obo:CL_0002083 "type I cell of adrenal medulla") EquivalentClasses(obo:CL_0002083 ObjectIntersectionOf(obo:CL_0000336 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001236) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0048243))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002083 obo:CL_0000336) # Class: obo:CL_0002084 (Boettcher cell) @@ -14518,7 +14108,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002087 "FMA:62855") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002087 "agranular leukocyte") AnnotationAssertion(rdfs:label obo:CL_0002087 "nongranular leukocyte") EquivalentClasses(obo:CL_0002087 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:CL_4030045 obo:GO_0030141))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002087 obo:CL_0000738) # Class: obo:CL_0002088 (interstitial cell of Cajal) @@ -14532,7 +14121,6 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:pr") oboInOwl:hasExactSyn AnnotationAssertion(rdfs:comment obo:CL_0002088 "Some argue this cell type is of mesenchymal origin.") AnnotationAssertion(rdfs:label obo:CL_0002088 "interstitial cell of Cajal") EquivalentClasses(obo:CL_0002088 ObjectIntersectionOf(obo:CL_0000710 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043134))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002088 obo:CL_0000710) # Class: obo:CL_0002089 (group 2 innate lymphoid cell, mouse) @@ -14581,7 +14169,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0002092 "MESH:D001854") AnnotationAssertion(rdfs:comment obo:CL_0002092 "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.") AnnotationAssertion(rdfs:label obo:CL_0002092 "bone marrow cell") EquivalentClasses(obo:CL_0002092 ObjectIntersectionOf(obo:CL_0001035 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002371))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002092 obo:CL_0001035) # Class: obo:CL_0002093 (secondary polar body) @@ -14639,7 +14226,6 @@ AnnotationAssertion(rdfs:label obo:CL_0002097 "cortical cell of adrenal gland") EquivalentClasses(obo:CL_0002097 ObjectIntersectionOf(obo:CL_0002078 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001235))) SubClassOf(obo:CL_0002097 obo:CL_0000150) SubClassOf(obo:CL_0002097 obo:CL_0000174) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002097 obo:CL_0002078) # Class: obo:CL_0002098 (regular cardiac myocyte) @@ -14662,7 +14248,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002099 "epithelial cell of AnnotationAssertion(rdfs:label obo:CL_0002099 "type I cell of adrenal cortex") EquivalentClasses(obo:CL_0002099 ObjectIntersectionOf(obo:CL_0002097 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002053))) SubClassOf(obo:CL_0002099 obo:CL_0000456) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002099 obo:CL_0002097) # Class: obo:CL_0002100 (regular interventricular cardiac myocyte) @@ -14685,7 +14270,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38-positive naive AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002101 "CD38-positive naive B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002101 "CD38-positive naive B cell") EquivalentClasses(obo:CL_0002101 ObjectIntersectionOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002101 obo:CL_0000788) # Class: obo:CL_0002102 (CD38-negative naive B cell) @@ -14699,7 +14283,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38-negative naive AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002102 "CD38-negative naive B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002102 "CD38-negative naive B cell") EquivalentClasses(obo:CL_0002102 ObjectIntersectionOf(obo:CL_0000788 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002102 obo:CL_0000788) # Class: obo:CL_0002103 (IgG-positive double negative memory B cell) @@ -14721,7 +14304,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive double AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002103 "IgG-positive double negative memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002103 "IgG-positive double negative memory B cell") EquivalentClasses(obo:CL_0002103 ObjectIntersectionOf(obo:CL_0000981 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071735))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002103 obo:CL_0000981) # Class: obo:CL_0002104 (IgG-negative double negative memory B cell) @@ -14743,7 +14325,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative double AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002104 "IgG-negative double negative memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002104 "IgG-negative double negative memory B cell") EquivalentClasses(obo:CL_0002104 ObjectIntersectionOf(obo:CL_0000981 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002104 obo:CL_0000981) # Class: obo:CL_0002105 (CD38-positive IgG memory B cell) @@ -14757,28 +14338,24 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38-positive IgG m AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002105 "CD38-positive IgG memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002105 "CD38-positive IgG memory B cell") EquivalentClasses(obo:CL_0002105 ObjectIntersectionOf(obo:CL_0000979 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002105 obo:CL_0000979) # Class: obo:CL_0002106 (IgD-positive CD38-positive IgG memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002106 "An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive.") AnnotationAssertion(rdfs:label obo:CL_0002106 "IgD-positive CD38-positive IgG memory B cell") EquivalentClasses(obo:CL_0002106 ObjectIntersectionOf(obo:CL_0002105 ObjectSomeValuesFrom(obo:RO_0002104 obo:GO_0071738))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002106 obo:CL_0002105) # Class: obo:CL_0002107 (IgD-negative CD38-positive IgG memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002107 "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive.") AnnotationAssertion(rdfs:label obo:CL_0002107 "IgD-negative CD38-positive IgG memory B cell") EquivalentClasses(obo:CL_0002107 ObjectIntersectionOf(obo:CL_0002105 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002107 obo:CL_0002105) # Class: obo:CL_0002108 (CD38-negative IgG memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002108 "A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.") AnnotationAssertion(rdfs:label obo:CL_0002108 "CD38-negative IgG memory B cell") EquivalentClasses(obo:CL_0002108 ObjectIntersectionOf(obo:CL_0000979 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071738) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002108 obo:CL_0000979) # Class: obo:CL_0002109 (B220-positive CD38-positive naive B cell) @@ -14796,14 +14373,12 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B- AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002109 "CD38+B220+ naive B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002109 "B220-positive CD38-positive naive B cell") EquivalentClasses(obo:CL_0002109 ObjectIntersectionOf(obo:CL_0002101 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002109 obo:CL_0002101) # Class: obo:CL_0002110 (B220-low CD38-positive naive B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002110 "A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.") AnnotationAssertion(rdfs:label obo:CL_0002110 "B220-low CD38-positive naive B cell") EquivalentClasses(obo:CL_0002110 ObjectIntersectionOf(obo:CL_0002101 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002110 obo:CL_0002101) # Class: obo:CL_0002111 (CD38-negative unswitched memory B cell) @@ -14817,21 +14392,18 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38-negative unswi AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002111 "CD38-negative unswitched memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002111 "CD38-negative unswitched memory B cell") EquivalentClasses(obo:CL_0002111 ObjectIntersectionOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002111 obo:CL_0000970) # Class: obo:CL_0002112 (B220-positive CD38-negative unswitched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002112 "A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002112 "B220-positive CD38-negative unswitched memory B cell") EquivalentClasses(obo:CL_0002112 ObjectIntersectionOf(obo:CL_0002111 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002112 obo:CL_0002111) # Class: obo:CL_0002113 (B220-low CD38-negative unswitched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002113 "A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002113 "B220-low CD38-negative unswitched memory B cell") EquivalentClasses(obo:CL_0002113 ObjectIntersectionOf(obo:CL_0002111 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002113 obo:CL_0002111) # Class: obo:CL_0002114 (CD38-positive unswitched memory B cell) @@ -14845,21 +14417,18 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38-positive unswi AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002114 "CD38-positive unswitched memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002114 "CD38-positive unswitched memory B cell") EquivalentClasses(obo:CL_0002114 ObjectIntersectionOf(obo:CL_0000970 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002114 obo:CL_0000970) # Class: obo:CL_0002115 (B220-positive CD38-positive unswitched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002115 "A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002115 "B220-positive CD38-positive unswitched memory B cell") EquivalentClasses(obo:CL_0002115 ObjectIntersectionOf(obo:CL_0002114 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002115 obo:CL_0002114) # Class: obo:CL_0002116 (B220-low CD38-positive unswitched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002116 "A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002116 "B220-low CD38-positive unswitched memory B cell") EquivalentClasses(obo:CL_0002116 ObjectIntersectionOf(obo:CL_0002114 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002116 obo:CL_0002114) # Class: obo:CL_0002117 (IgG-negative class switched memory B cell) @@ -14873,49 +14442,42 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG-negative class AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002117 "IgG-negative class switched memory B-lymphocyte") AnnotationAssertion(rdfs:label obo:CL_0002117 "IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002117 ObjectIntersectionOf(obo:CL_0000972 ObjectSomeValuesFrom(obo:CL_4030046 obo:GO_0071735))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002117 obo:CL_0000972) # Class: obo:CL_0002118 (CD38-negative IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002118 "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002118 "CD38-negative IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002118 ObjectIntersectionOf(obo:CL_0002117 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002118 obo:CL_0002117) # Class: obo:CL_0002119 (CD38-positive IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002119 "A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002119 "CD38-positive IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002119 ObjectIntersectionOf(obo:CL_0002117 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001408))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002119 obo:CL_0002117) # Class: obo:CL_0002120 (CD24-positive CD38-negative IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002120 "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002120 "CD24-positive CD38-negative IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002120 ObjectIntersectionOf(obo:CL_0002118 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001932))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002120 obo:CL_0002118) # Class: obo:CL_0002121 (CD24-negative CD38-negative IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002121 "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002121 "CD24-negative CD38-negative IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002121 ObjectIntersectionOf(obo:CL_0002118 ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001932))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002121 obo:CL_0002118) # Class: obo:CL_0002122 (B220-positive CD38-positive IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002122 "A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative.") AnnotationAssertion(rdfs:label obo:CL_0002122 "B220-positive CD38-positive IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002122 ObjectIntersectionOf(obo:CL_0002119 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002122 obo:CL_0002119) # Class: obo:CL_0002123 (B220-low CD38-positive IgG-negative class switched memory B cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:dsd") Annotation(oboInOwl:hasDbXref "GOC:rhs") Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:20123131") obo:IAO_0000115 obo:CL_0002123 "A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive.") AnnotationAssertion(rdfs:label obo:CL_0002123 "B220-low CD38-positive IgG-negative class switched memory B cell") EquivalentClasses(obo:CL_0002123 ObjectIntersectionOf(obo:CL_0002119 ObjectSomeValuesFrom(obo:RO_0015016 obo:PR_000001014))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002123 obo:CL_0002119) # Class: obo:CL_0002124 (CD27-positive gamma-delta T cell) @@ -14926,7 +14488,6 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002124 "gammadelta27-positi AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0002124 "gd27-positive") AnnotationAssertion(rdfs:label obo:CL_0002124 "CD27-positive gamma-delta T cell") EquivalentClasses(obo:CL_0002124 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032609) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002124 obo:CL_0000800) SubClassOf(obo:CL_0002124 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002126)) # Class: obo:CL_0002125 (CD27-negative gamma-delta T cell) @@ -14937,7 +14498,6 @@ AnnotationAssertion(oboInOwl:creation_date obo:CL_0002125 "2010-08-18T09:57:29Z" AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:21976777") oboInOwl:hasExactSynonym obo:CL_0002125 "gammadelta-17 cells") AnnotationAssertion(rdfs:label obo:CL_0002125 "CD27-negative gamma-delta T cell") EquivalentClasses(obo:CL_0002125 ObjectIntersectionOf(obo:CL_0000800 ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000003455) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001963) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0032620) ObjectSomeValuesFrom(obo:RO_0002353 obo:GO_0030217))) -SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0002125 obo:CL_0000800) SubClassOf(obo:CL_0002125 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0002126)) # Class: obo:CL_0002126 (CD25-positive, CD27-positive immature gamma-delta T cell) @@ -14947,7 +14507,6 @@ AnnotationAssertion(terms:contributor obo:CL_0002126 ) ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742)) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000031)) -) +) \ No newline at end of file diff --git a/src/sparql/remove-subclass-inferred-annotation.ru b/src/sparql/remove-subclass-inferred-annotation.ru new file mode 100644 index 000000000..ef14a61e3 --- /dev/null +++ b/src/sparql/remove-subclass-inferred-annotation.ru @@ -0,0 +1,24 @@ +PREFIX oboInOwl: +PREFIX owl: +PREFIX rdfs: + +DELETE { + ?sub rdfs:subClassOf ?super . + + ?axiom a owl:Axiom ; + owl:annotatedSource ?sub ; + owl:annotatedProperty rdfs:subClassOf ; + owl:annotatedTarget ?super ; + oboInOwl:is_inferred "true" . + +} +WHERE { + ?sub rdfs:subClassOf ?super . + ?axiom a owl:Axiom ; + owl:annotatedSource ?sub ; + owl:annotatedProperty rdfs:subClassOf ; + owl:annotatedTarget ?super ; + oboInOwl:is_inferred "true" . + FILTER (ISIRI(?sub) && (STRSTARTS(STR(?sub), "http://purl.obolibrary.org/obo/CL_"))) +} +