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index.html
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---
layout: default
title: Home
---
<header>
<div id="carouselExampleIndicators" class="carousel slide" data-ride="carousel" data-interval="10000">
<div class="carousel-inner text-center" role="listbox">
<!-- Slide 1 -->
<div class="carousel-item active" style="background-image: url('assets/img/homepage-hero-generic.jpg')">
<div class="d-flex h-100 align-items-center justify-content-center">
<div class="w-75 text-white">
<img src="assets/img/ot-logo-white.png" style="width:200px;" alt="Open Targets helix logo and wordmark in white" class="mb-2"/>
<h2 class="mt-2">
<b>Developing safe and effective drugs is difficult and expensive</b>
</h2>
<h3 style="font-size:22px">
We are dedicated to changing this with innovative experimental and informatics approaches
</h3>
</div>
</div>
</div>
<!-- Slide 2 -->
<div class="carousel-item" style="background-image: url('assets/img/homepage-hero-platform.jpg')">
<div class="d-flex h-100 align-items-center justify-content-center">
<div class="p-4 w-75" style="background-color: white;">
<h2 class="mb-4">The Open Targets Platform</h2>
<p>
A freely-available, comprehensive, and open source tool that
aggregates multiple public data sources and helps scientists
identify and prioritise potential therapeutic drug targets for
further investigation.
</p>
<a href="https://platform.opentargets.org" class="btn btn-primary">Visit the Open Targets Platform</a>
</div>
</div>
</div>
<!-- Slide 3 -->
<div class="carousel-item" style="background-image: url('assets/img/homepage-hero-genetics.jpg')">
<div class="d-flex h-100 align-items-center justify-content-center">
<div class="p-4 w-75" style="background-color: white;">
<h2 class="mb-4">Open Targets Genetics</h2>
<p>
A freely-available, open source tool that highlights variant-centric statistical
evidence to allow both prioritisation of candidate causal variants at
trait-associated loci, and identification of potential drug targets.
</p>
<a href="https://genetics.opentargets.org/" class="btn btn-primary">Visit Open Targets Genetics</a>
</div>
</div>
</div>
</div>
<a class="carousel-control-prev" href="#carouselExampleIndicators" role="button" data-slide="prev">
<span class="carousel-control-prev-icon" aria-hidden="true"></span>
<span class="sr-only">Previous</span>
</a>
<a class="carousel-control-next" href="#carouselExampleIndicators" role="button" data-slide="next">
<span class="carousel-control-next-icon" aria-hidden="true"></span>
<span class="sr-only">Next</span>
</a>
</div>
</header>
<section class="py-5 my-5">
<div class="container">
<div class="row mb-3">
<div class="col-lg-12">
<p>
Open Targets is an innovative, large-scale, multi-year, public-private
partnership that uses human genetics and genomics data for systematic drug
target identification and prioritisation.
</p>
<p>
Visit the <a href="https://platform.opentargets.org">Open Targets Platform</a>
which integrates public domain data to enable target identification and
prioritisation, or <a href="https://genetics.opentargets.org/">Open Targets
Genetics</a> which identifies targets based on GWAS and functional
genomics. We complement data integration with large scale systematic experimental approaches
to support target identification, prioritisation and validation. Check out
<a href="/publications">our latest papers</a> describing our experimental target
identification approaches in oncology, neurodegeneration, and immunity and inflammation.
</p>
</div>
</div>
<div class="row">
<div class="col-12 text-center">
<a href="https://platform.opentargets.org" class="btn btn-primary">
<b>Find targets for a given disease</b><br /><small>Visit the Open Targets Platform</small>
</a>
<a href="https://genetics.opentargets.org/" class="ml-md-4 mt-2 mt-sm-2 mt-md-0 btn btn-primary">
<b>Discover genetic evidence for targets</b><br /><small>Visit Open Targets Genetics</small>
</a>
<a href="/publications" class="ml-md-4 mt-2 mt-sm-2 mt-md-0 btn btn-primary">
<b>Explore our research projects</b><br /><small>Read our publications</small>
</a>
</div>
</div>
</div>
</section>
<div class="container">
<hr />
</div>
<section class="py-5 my-5">
<div class="container">
<div class="row">
<div class="col-lg-12">
<h2 class="text-center mb-5">News</h2>
</div>
{% assign all_news = site.news | sort: 'date' | reverse %}
{% for news_item in all_news limit:1 %}
{% include news_item.html %}
{% endfor %}
<div class="col-lg-12 mt-5">
<p class="text-center">
<a href="/news">Read more news about Open Targets</a>
</a>
</div>
</div>
</div>
</section>
<div class="container">
<hr />
</div>
<section class="py-5 my-5">
<div class="container">
<div class="row">
<div class="col-lg-12">
<h2 class="text-center mb-5">Our Partners</h2>
<p>
At the heart of Open Targets is a consortium of complementary <a href="/partners">partner institutions</a>
that bring their respective expertise to collaborative projects that improve how we systematically identify and
prioritise drug targets.
</p>
</div>
</div>
<div class="row mt-3 d-flex justify-content-center align-items-center">
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2">
<a href="https://www.ebi.ac.uk/" target="_blank">
<img src="assets/img/logos/embl-ebi.png" class="img-fluid">
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.gene.com/" target="_blank">
<img src="assets/img/logos/genentech.png" class="img-fluid"/>
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.gsk.com" target="_blank">
<img src="assets/img/logos/gsk.png" class="img-fluid"/>
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.msd.com/" target="_blank">
<img src="assets/img/logos/msd.png" class="img-fluid"/>
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.pfizer.com/" target="_blank">
<img src="assets/img/logos/pfizer.png" class="img-fluid" />
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.sanofi.com/" target="_blank">
<img src="assets/img/logos/sanofi.png" class="img-fluid" />
</a>
</div>
<div class="col-lg-3 col-md-6 col-sm-6 col-6 py-2 d-flex justify-content-center">
<a href="https://www.sanger.ac.uk" target="_blank">
<img src="assets/img/logos/wellcome-sanger.png" class="img-fluid"/>
</a>
</div>
</div>
</div>
</section>
<div class="container">
<hr />
</div>
<section class="py-5 my-5">
<div class="container">
<div class="row">
<div class="col-lg-12">
<h2 class="text-center mb-5">Our Principles</h2>
<div class="row">
<div class="col-lg-4 col-md-6 py-3">
<div class="card">
<div class="bg-blue text-center">
<span class="principles-cta-icon">
<i class="fas fa-crosshairs"></i>
</span>
</div>
<div class="card-body text-center">
<h5 class="card-title">A systematic approach</h5>
<p class="card-text">
Systematically identify and prioritise the best targets to safely and
effectively treat rare and common diseases
</p>
<div class="text-center">
<a href="/science" class="btn btn-primary">Our scientific approach</a>
</div>
</div>
</div>
</div>
<div class="col-lg-4 col-md-6 py-3">
<div class="card">
<div class="text-center bg-blue">
<span class="principles-cta-icon">
<i class="fas fa-book-open"></i>
</span>
</div>
<div class="card-body text-center">
<h5 class="card-title">Rapid publication</h5>
<p class="card-text">
We are committed to rapid publication and making data, methods and results
publicly available as soon as possible
</p>
<div class="text-center">
<a href="/publications" class="btn btn-primary">Our latest publications</a>
</div>
</div>
</div>
</div>
<div class="col-lg-4 col-md-6 py-3">
<div class="card">
<div class="text-center bg-blue">
<span class="principles-cta-icon">
<i class="fas fa-exchange-alt"></i>
</span>
</div>
<div class="card-body text-center">
<h5 class="card-title">Open collaboration</h5>
<p class="card-text">
We believe in non-exclusive partnerships that foster the free exchange
of ideas, expertise, and data
</p>
<div class="text-center">
<a href="/partners" class="btn btn-primary">Our partners and collaborators</a>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</div>
</section>
<div class="container">
<hr />
</div>
<section class="py-5 my-5">
<div class="container">
<div class="row">
<div class="col-lg-12">
<h2 class="text-center mb-5">Follow Us</h2>
</div>
</div>
<div class="row">
<div class="col-lg-6 py-3">
<div class="news-section-header">
<h4 class="text-center">
<a href="https://blog.opentargets.org/" target="_blank">
<i class="fas fa-rss-square"></i>
Blog
</a>
</h4>
</div>
<hr />
<div class="news-section-content">
<div id="blog-section">
{% for post in site.data.ghost_api_response.posts %}
<a class="font-weight-bold mb-1" href="http://blog.opentargets.org/{{post.slug}}" target="_blank">
{{ post.title }}
</a>
<p class="mb-1 font-weight-light">
{% for author in post.authors %}
{{author.name}}{% unless forloop.last %},{% endunless %}
{% endfor %}
</p>
<p class="mb-1 font-weight-light">{{ post.published_at | date: "%-d %B %Y"}} </p>
<p class="mb-4">{{post.meta_description}}</p>
{% endfor %}
</div>
</div>
</div>
<div class="col-lg-6 py-3">
<div class="news-section-header">
<h4 class="text-center">
<a href="https://twitter.com/opentargets" target="_blank">
<i class="fab fa-twitter-square"></i>
Twitter
</a>
</h4>
</div>
<hr />
<div class="news-section-content">
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
<a
class="twitter-timeline"
data-lang="en"
data-height="400"
data-theme="light"
data-chrome="noborders noheader nofooter"
href="https://twitter.com/opentargets">
Tweets by @opentargets
</a>
</div>
</div>
</div>
</div>
</section>