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minor edits and removes mentions of federated
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danamouk committed Oct 4, 2023
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4 changes: 2 additions & 2 deletions content/en/_index.html
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The Note module contains deidentified free-text clinical notes for hospitalized patients.
{{% /blocks/feature %}}

{{% blocks/feature icon="fa-lightbulb" title="MIMIC-IV-Fed" url="/docs/iv/federated/" %}}
MIMIC-Fed is a large federated COVID-rich ICU database comprising deidentified health-related data from Beth Israel Deaconess Medical Center (BIDMC) and Northwestern Memorial Health Center (NMHC) from 2020 to 2022.
{{% blocks/feature icon="fa-lightbulb" title="MIMIC-Northwestern" url="/docs/multi-center/" %}}
MIMIC-Northwestern is a large harmonized multi-center COVID-rich ICU database comprising deidentified health-related data from Beth Israel Deaconess Medical Center (BIDMC) and Northwestern Memorial HealthCare (NMHC) from 2020 to 2022.
{{% /blocks/feature %}}

{{% blocks/feature icon="fa-scroll" title="MIMIC-III" url="/docs/iii/" %}}
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31 changes: 0 additions & 31 deletions content/en/docs/federated/_index.md

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31 changes: 31 additions & 0 deletions content/en/docs/multi-center/_index.md
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---
title: "MIMIC-Northwestern: A Harmonized Multi-center COVID-rich ICU Database documentation"
linktitle: Multi-center
weight: 40

cascade:
- type: "docs"
_target:
path: "/**"

# description: >
# We introduce a large harmonized multi-center COVID-rich ICU database comprising deidentified health-related data from Beth Israel Deaconess Medical Center (BIDMC) and Northwestern Memorial HealthCare (NMHC) from 2020 to 2022.
---
We introduce MIMIC-Northwestern, a large harmonized multi-center COVID-rich ICU database comprising deidentified health-related data from Beth Israel Deaconess Medical Center (BIDMC) and Northwestern Memorial HealthCare (NMHC) from 2020 to 2022, capturing the evolving distribution shifts in data over this critical time period. The database adopts a similar data structure as MIMIC-IV v2.2.

Notably, Northwestern Memorial HealthCare (NMHC) uses the Epic electronic medical records (EMR) system. To make the EMR data available for research and quality assurance, the NM EMR systems transfer selected data into a relational Enterprise Data Warehouse (NM EDW).

The NM EDW tables are categorized into two primary categories, Fact and Dimension, following data warehousing conventions. As implemented in the NM EDW, Fact tables primarily contain events (such as encounters, admissions, diagnosis events, procedure orders, and medication orders), while Dimension tables describe persistent attributes of entities (patients, procedure names, the medication formulary).

The NM EDW also includes auxiliary tables not directly related to patient care, such as a list of International Classification of Disease codes (ICD-9 and ICD-10). In response to the COVID-19/SARS-COV-2 pandemic, a COVID-19 data mart was created within the EDW to provide convenient access to information on COVID-19 patients, lab results, medications and treatments.

The multi-center database is currently organized into two distinct modules to highlight the source of the data:

- [Hosp](/docs/federated/modules/hosp/) - Hospital level data including patients, admissions, labs, ICD diagnoses for billing purposes, prescriptions, and electronic medication administration records.
- [ICU](/docs/federated/modules/icu/) - ICU level data including icu stays, procedure events, chartevents (vital signs).

{{% pageinfo %}}
The multi-center database is not yet released and its structure is subject to change.
{{% /pageinfo %}}

The tables structures adopted to align with MIMIC's data structure for each module are detailed in the respective sections. Additionally, we have incorporated COVID-related concepts and standard terminologies (LOINC, RxNorm, SNOMED, ICD-9/10) and derived mappings (for drug administration) into the dataset. This integration not only facilitates current multi-center initiatives, but also facilities interoperability, allowing for seamless data exchange and collaboration across healthcare systems.
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weight: 3
date: 2023-09-18
description: >
Description of the data contained in each of the MIMIC-Fed modules.
Description of the data contained in each of the multi-center modules.
---

Data within the modules will be made available on PhysioNet.
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The Hosp module comprises data sourced from the comprehensive Electronic Health Record (EHR) systems of both BIDMC and NMHC hospitals. Information covered includes patient and admission information, laboratory measurements, billed diagnoses, medication orders, and electronic medication administration records.
---

The HOSP module contains data derived from the hospital wide EHR of BIDMC and NMHC. These measurements are predominantly recorded during the hospital stay, though some tables include data from outside the hospital as well (e.g. outpatient laboratory tests in *labevents*).
The Hosp module contains data derived from the hospital wide EHR of BIDMC and NMHC. These measurements are predominantly recorded during the hospital stay, though some tables include data from outside the hospital as well (e.g. outpatient laboratory tests in *labevents*).

Information includes patient and admission details (*patients*, *admissions*), laboratory measurements (*labevents*, *d_labitems*), hospital billing information (*diagnoses_icd*, *d_icd_diagnoses*), medication orders (*prescriptions*), and electronic medication administration records (*emar*).

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### `insurance`, `language`, `marital_status`, `race`, `ethnicity`

The `insurance`, `language`, `marital_status`, and `race` and `ethnicity` columns provide information about patient demographics for the given hospitalization. Note, in BIDMC there is only one column for `race`, however we have added `ethnicity` column to federate NMHC's data.
The `insurance`, `language`, `marital_status`, and `race` and `ethnicity` columns provide information about patient demographics for the given hospitalization. Note, in BIDMC there is only one column for `race`, however we have added `ethnicity` column to incorporate NMHC's data.

The race column in NMHC includes:

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For the data sourced from NMHC, Illinois law defines certain categories of information as Sensitive Protected Health Information (SPHI) which require special treatment. SPHI includes genetic counseling but does not include genetic testing.

To facilitate further federation processes, the lab mappings to standard terminologies (LOINC) will be released.
To facilitate further multi-center initiatives, the lab mappings to standard terminologies (LOINC) will be released.

### Links to

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The *prescriptions* table provides information about prescribed medications. Information includes the name of the drug, coded identifiers including the Generic Sequence Number (GSN) and National Drug Code (NDC), the product strength, the formulary dose, and the route of administration.

To facilitate further federation processes, the drug mappings to standard terminologies (RxNorm) will be released.
To facilitate further multi-center initiatives, the drug mappings to standard terminologies (RxNorm) will be released.

We provide a list of some common COVID-19 drugs in the database, as defined by RxNorm terminology, below:

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The *d_items* table defines `itemid`, which represents measurements in the database. Measurements of the same type (e.g. heart rate) will have the same `itemid` (e.g. 220045). Values in the `itemid` column are unique to each row. All `itemid`s will have a value > 220000.

To faciliate future federation processes, we will release mappings within charted events (including vital signs) to standard terminologies (LOINC) and mappings for procedure events to standard terminologies (SNOMED).
To faciliate future multi-center initiatives, we will release mappings within charted events (including vital signs) to standard terminologies (LOINC) and mappings for procedure events to standard terminologies (SNOMED).


We provide a list of common vital sign labels in the database, as defined by LOINC terminology, below:
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