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"README.md"

author: "E Flynn"

date: "4/27/2018"

Human liver meta-analysis project.

Performs Meta-analysis of liver expression data.

The directory search_code contains the code that was used for searching GEO and processing the search results.

  • The results of this are located in data/search_res

The data was pre-processed using the file: load_extract_sex_label.R. Briefly, each dataset was downloaded, filtered for normal liver samples, expression data normalized and mapped to genes, and sex labels extracted.

  • This results in the files ds1g - ds17g.RData located in data/processed/
  • Each of these files contains an .RData object with a particular processed dataset.

The bulk of the analysis is then done using: LiverMA.Rmd.

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Sex-differential liver meta-analysis

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