Sierra 2.3.3

In this release, we updated the list of usual/unusual mutations, the list of signature APOBEC mutations, and the list of APOBEC context drug resistance mutations. The latest version of the three lists are included in the HIVFacts library (previously known as "HIV-AAPcnt") as version 2019.8.

This is the first time since 2016 we updated our APOBEC-related lists. The steps of identifying signature APOBEC mutations and APOBEC context DRMs were described in this document: HIV-1 Signature APOBEC Mutations.