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Fixes #1889 neuroendocrine cell #2235

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11 changes: 3 additions & 8 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -5097,20 +5097,15 @@ SubClassOf(obo:CL_0000164 obo:CL_0000163)

# Class: obo:CL_0000165 (neuroendocrine cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D055099") obo:IAO_0000115 obo:CL_0000165 "A neuron that is capable of some hormone secretion in response to neuronal signals.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "MESH:D055099") Annotation(oboInOwl:hasDbXref "PMID:2675281") obo:IAO_0000115 obo:CL_0000165 "An endocrine cell that is part of the neuroendocrine system. A neuroendocrine cell secretes hormones into the circulatory system in response to direct stimuli.")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000165 "BTO:0002691")
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000165 "FMA:83810")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000165 "neurosecretory cell")
AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000165 "neurosecretory neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:5342440") Annotation(oboInOwl:hasDbXref "https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073") rdfs:comment obo:CL_0000165 "The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements.

The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.")
AnnotationAssertion(rdfs:label obo:CL_0000165 "neuroendocrine cell")
EquivalentClasses(obo:CL_0000165 ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046879)))
EquivalentClasses(obo:CL_0000165 ObjectIntersectionOf(obo:CL_0000163 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_8600018)))
SubClassOf(obo:CL_0000165 obo:CL_0000163)
SubClassOf(obo:CL_0000165 obo:CL_0000393)
SubClassOf(obo:CL_0000165 obo:CL_0000527)
SubClassOf(obo:CL_0000165 obo:CL_0000710)

# Class: obo:CL_0000166 (chromaffin cell)

Expand Down Expand Up @@ -24946,6 +24941,7 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") oboInOwl:hasE
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33355253") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_1000223 "PNEC")
AnnotationAssertion(rdfs:label obo:CL_1000223 "lung neuroendocrine cell")
EquivalentClasses(obo:CL_1000223 ObjectIntersectionOf(obo:CL_0000165 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002048)))
SubClassOf(obo:CL_1000223 obo:CL_0000082)
SubClassOf(obo:CL_1000223 obo:CL_0000206)
SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0031045))
SubClassOf(obo:CL_1000223 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001820))
Expand Down Expand Up @@ -26184,7 +26180,6 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1000426 "FMA:69794")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GO:0061104") oboInOwl:hasExactSynonym obo:CL_1000426 "adrenal chromaffin cell")
AnnotationAssertion(rdfs:label obo:CL_1000426 "chromaffin cell of adrenal gland")
EquivalentClasses(obo:CL_1000426 ObjectIntersectionOf(obo:CL_0000166 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002369)))
SubClassOf(obo:CL_1000426 obo:CL_0000150)
SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_1000426 obo:CL_0000166)

# Class: obo:CL_1000427 (adrenal cortex chromaffin cell)
Expand Down
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